Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Damien Grégoire"'
Ras/MAPK signalling intensity defines subclonal fitness in a mouse model of hepatocellular carcinoma
Autor:
Anthony Lozano, Francois-Régis Souche, Carine Chavey, Valérie Dardalhon, Christel Ramirez, Serena Vegna, Guillaume Desandre, Anaïs Riviere, Amal Zine El Aabidine, Philippe Fort, Leila Akkari, Urszula Hibner, Damien Grégoire
Publikováno v:
eLife, Vol 12 (2023)
Quantitative differences in signal transduction are to date an understudied feature of tumour heterogeneity. The MAPK Erk pathway, which is activated in a large proportion of human tumours, is a prototypic example of distinct cell fates being driven
Externí odkaz:
https://doaj.org/article/a6847e4afd534521b7463f84208c628a
Autor:
Yannick Simonin, Serena Vegna, Leila Akkari, Damien Grégoire, Etienne Antoine, Jacques Piette, Nicolas Floc'h, Patrice Lassus, Guann-Yi Yu, Arielle R Rosenberg, Michael Karin, David Durantel, Urszula Hibner
Publikováno v:
PLoS Pathogens, Vol 9, Iss 3, p e1003234 (2013)
Exposure to hepatitis C virus (HCV) typically results in chronic infection that leads to progressive liver disease ranging from mild inflammation to severe fibrosis and cirrhosis as well as primary liver cancer. HCV triggers innate immune signaling w
Externí odkaz:
https://doaj.org/article/aba6c2c467324ee39aea21eea458e347
Autor:
Pierre Khalfi, Zoé Denis, Giovanni Merolla, Carine Chavey, José Ursic-Bedoya, Lena Soppa, Leonora Szirovicza, Udo Hetzel, Jeremy Dufourt, Cedric Leyrat, Nora Goldmann, Kaku Goto, Eloi Verrier, Thomas F. Baumert, Dieter Glebe, Valérie Courgnaud, Damien Grégoire, Jussi Hepojoki, Karim Majzoub
The recent discovery of Hepatitis D (HDV)-likeviruses across a wide range of taxa led to the establishment of theKolmioviridaefamily. Recent studies suggest that kolmiovirids can be satellites of viruses other than Hepatitis B virus (HBV), challengin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::071e6776eb010cac80aab2f9203ac64e
https://doi.org/10.1101/2023.05.17.541162
https://doi.org/10.1101/2023.05.17.541162
Autor:
Anthony Lozano, Francois-Régis Souche, Carine Chavey, Valérie Dardalhon, Christel Ramirez, Serena Vegna, Guillaume Desandre, Anaïs Riviere, Amal Zine El Aabidine, Philippe Fort, Leila Akkari, Urszula Hibner, Damien Grégoire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f697ab367654f5a3200c05ceb299dd9
https://doi.org/10.7554/elife.76294.sa2
https://doi.org/10.7554/elife.76294.sa2
Autor:
Marine Pratlong, Eric Fabbrizio, Lakdhar Khellaf, Nelly Pirot, Amélie Sarrazin, Damien Grégoire, Yannick Perez, Shefqet Hajdari, Jean-Yohan Noël, Eric Julien, Nehmé Saksouk, Aliki Zavoriti, Florence Cammas, Céline Graber, Célia Barrachina
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2020, 39 (13), pp.2676-2691. ⟨10.1038/s41388-020-1177-8⟩
Oncogene, Nature Publishing Group, 2020, 39 (13), pp.2676-2691. ⟨10.1038/s41388-020-1177-8⟩
International audience; Chromatin organization is essential for appropriate interpretation of the genetic information. Here, we demonstrated that the chromatin associated proteins HP1 are dispensable for hepatocytes survival but are essential within
Autor:
Damien Grégoire, Urszula Hibner, Leila Akkari, Philippe Fort, Amal Zine El Aabidine, Valérie Dardalhon, Anaïs Riviere, Guillaume Desandré, Serena Vegna, Christel Ramirez, François-Régis Souche, Anthony Lozano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e51153f6698db341151792c07953d8cc
https://doi.org/10.15252/rc.2022340572
https://doi.org/10.15252/rc.2022340572
Autor:
Timothy J. Mead, Urszula Hibner, Sylvie Richelme, Fabrice Daian, Damien Grégoire, Ahmed Abdouni, Anthony Lozano, María Arechederra, Sehrish K. Bazai, Rosanna Dono, Celia Sequera, Suneel S. Apte, Flavio Maina, Stéphane Audebert, Daniela S. Allende
Publikováno v:
Journal of Hepatology
Journal of Hepatology, Elsevier, 2020, ⟨10.1016/j.jhep.2020.11.008⟩
Journal of Hepatology, 2021, ⟨10.1016/j.jhep.2020.11.008⟩
Journal of Hepatology, Elsevier, 2020, ⟨10.1016/j.jhep.2020.11.008⟩
Journal of Hepatology, 2021, ⟨10.1016/j.jhep.2020.11.008⟩
Background & Aims The tumour microenvironment shapes tumour growth through cellular communications that include both direct interactions and secreted factors. The aim of this study was to characterize the impact of the secreted glycoprotein ADAMTSL5,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cdb4960f469c2367eace3d3b64537a9
https://hal.archives-ouvertes.fr/hal-03049722
https://hal.archives-ouvertes.fr/hal-03049722
Autor:
José Ursic-Bedoya, Guillaume Desandré, Carine Chavey, Pauline Marie, Arnaud Polizzi, Benjamin Rivière, Hervé Guillou, Eric Assenat, Urszula Hibner, Damien Gregoire
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 2, Pp 238-250 (2024)
Abstract FGF19 hormone has pleiotropic metabolic functions, including the modulation of insulin sensitivity, glucose/lipid metabolism and energy homeostasis. On top of its physiological metabolic role, FGF19 has been identified as a potentially targe
Externí odkaz:
https://doaj.org/article/68cb2332a4b943b799d98165f62d5be6
Autor:
Pierre Khalfi, Zoé Denis, Joe McKellar, Giovanni Merolla, Carine Chavey, José Ursic-Bedoya, Lena Soppa, Leonora Szirovicza, Udo Hetzel, Jeremy Dufourt, Cedric Leyrat, Nora Goldmann, Kaku Goto, Eloi Verrier, Thomas F Baumert, Dieter Glebe, Valérie Courgnaud, Damien Gregoire, Jussi Hepojoki, Karim Majzoub
Publikováno v:
PLoS Pathogens, Vol 20, Iss 3, p e1012060 (2024)
The recent discovery of Hepatitis D (HDV)-like viruses across a wide range of taxa led to the establishment of the Kolmioviridae family. Recent studies suggest that kolmiovirids can be satellites of viruses other than Hepatitis B virus (HBV), challen
Externí odkaz:
https://doaj.org/article/ada71d4cf9dd4a64980a7c9aa774c4a5
Autor:
Susana Prieto, Katarina Bacevic, Urszula Hibner, Anthony Lozano, Jessica Zucman-Rossi, Daniel Fisher, José Ursic-Bedoya, Jacqueline Butterworth, Alain Camasses, Geronimo Dubra, Stefano Caruso, Damien Grégoire
Hepatocellular carcinoma (HCC) is a common cancer with high mortality. The limited therapeutic options for advanced disease include treatment with Sorafenib, a multi-kinase inhibitor whose targets include the Mediator kinase CDK8. Since CDK8 has repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae638a23bb15f7949d1dd8b8550cd2c