Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Damien Fleury"'
Autor:
Lucia M. Tovena, Damien Fleury Fleury
Publikováno v:
Quaderni di Linguistica e Studi Orientali, Vol 9 (2023)
Predicative modal superlatives, such as Italian Luisa è stata il più calma possibile (‘Luisa was the most unperturbed possible’), state that the highest amount of calm that could be instantiated in the type of situation at hand, was associated
Externí odkaz:
https://doaj.org/article/43aec2f07171471ebbd73fdedf6b55eb
Autor:
Christelle David, Nele Vandervoort, Damien Fleury, Denis Annoot, Laëtitia Cherel, Willem Jan Hengeveld, Thierry Christophe, Sameh H. Soror, Agnès Marie Joncour, Christopher Gaëtan Housseman, Alain Monjardet, R Galien, Patrick Mollat, Reginald Brys, Veronique Roncoroni, Luce Lepissier, Natacha Bienvenu, Lionel Vercheval, Alexandre Wohlkonig, Christophe Peixoto, Jörg Heiermann, Katja Conrath, Mia Jans, Sandrine Le Tallec, Bertrand Heckmann, Robert Touitou, Nicolas Desroy, Jan Steyaert, Virginie Labeguere, Gregor Pilzak, Ellen van der Aar, Xavier Marie Bock, Nicolas Triballeau, Emanuelle Wakselman
Publikováno v:
Journal of Medicinal Chemistry. 60:7371-7392
Autotaxin (ATX) is a secreted enzyme playing a major role in the production of lysophosphatidic acid (LPA) in blood through hydrolysis of lysophosphatidyl choline (LPC). The ATX-LPA signaling axis arouses a high interest in the drug discovery industr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1bab957aedfbab6da364d90d0e33f16
https://doi.org/10.1021/acs.jmedchem.7b00647
https://doi.org/10.1021/acs.jmedchem.7b00647
Autor:
Lucia M. Tovena, Damien Fleury
Publikováno v:
SHS Web of Conferences, Vol 46, p 12003 (2018)
Cette contribution porte sur les interprétations des interrogatives introduites par comment, qui peuvent interroger sur la manière mais aussi sur la cause, ou donner lieu à des questions parfois qualifiées de rhétoriques. Nous observons des affi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1311931d0c0a731c194f260b876fc867
https://doaj.org/article/6ce0ca3c171d40479684a584757550ca
https://doaj.org/article/6ce0ca3c171d40479684a584757550ca
Autor:
Reginald Brys, Emanuelle Wakselman, Lionel Vercheval, Christelle David, Nele Vandervoort, Laëtitia Cherel, Christopher Gaëtan Housseman, Luce Lepissier, Natacha Bienvenu, Mia Jans, Alain Monjardet, Agnès Marie Joncour, Nicolas Desroy, Gregor Pilzak, Willem Jan Hengeveld, Sandrine Le Tallec, Ellen van der Aar, Bertrand Heckmann, Nicolas Triballeau, Jan Steyaert, Patrick Mollat, Veronique Roncoroni, Virginie Labeguere, Sameh H. Soror, Damien Fleury, Thierry Christophe, Christophe Peixoto, Xavier Marie Bock, Denis Annoot, Jörg Heiermann, Katja Conrath, R Galien, Robert Touitou, Alexandre Wohlkonig
Publikováno v:
Journal of Medicinal Chemistry. 61:4270-4270
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93dee812f5866eca6cabf47d605a46ce
https://doi.org/10.1021/acs.jmedchem.8b00579
https://doi.org/10.1021/acs.jmedchem.8b00579
Expression, purification and functional characterization of Wnt signaling co-receptors LRP5 and LRP6
Autor:
Helene Lebhar, Corinne Gillard, Patrick Mollat, Robert Touitou, Damien Fleury, Georges Rawadi, Béatrice Vayssière
Publikováno v:
Protein Expression and Purification. 70:39-47
Activation of the Wnt signaling cascade plays a pivotal role during development and in various disease states. Wnt signals are transduced by seven-transmembrane Frizzled (Fz) proteins and the single-transmembrane LDL-receptor-related proteins 5 or 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::714b83aaeba260721f144b38bdf5d87e
https://doi.org/10.1016/j.pep.2009.08.012
https://doi.org/10.1016/j.pep.2009.08.012
Autor:
Damien Fleury, Catherine Robin-Jagerschmidt, Francois Nique, Patrick Mollat, Thierry Prangé, Maxime Thauvin
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 64:1159-1162
The ligand-binding domain of the human androgen receptor has been cloned, overproduced and crystallized in the presence of a coactivator-like 11-mer peptide and two different nonsteroidal ligands. The crystals of the two ternary complexes were isomor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c926194314729fdd7b629354a1e8675
https://doi.org/10.1107/s1744309108036683
https://doi.org/10.1107/s1744309108036683
Publikováno v:
Protein Expression and Purification. 52:96-103
Human cytosolic β-glucosidase is a monomeric enzyme that hydrolyzes various β- d -glycosides and its real physiological role remains unclear. Here, we describe the production of this enzyme in Sf9 cells with a N-terminal 6× His tag. The production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a34738bd6dabf3e5a005a417bad6b958
https://doi.org/10.1016/j.pep.2006.08.014
https://doi.org/10.1016/j.pep.2006.08.014
Autor:
Francois Nique, Denis Guédin, Nicolas Triballeau, Eric Duval, Jean-Michel Lemoullec, Denis Annoot, Catherine Robin-Jagerschmidt, Maxime Thauvin, Jean-Michel Lefrancois, Thierry Prangé, Laurence Michoux, Philippe Clément-Lacroix, Damien Fleury, Pierre Deprez, Patrick Mollat, Séverine Hebbe, Dominique Minet, Christophe Peixoto
Publikováno v:
Journal of medicinal chemistry. 55(19)
A novel selective androgen receptor modulator scaffold has been discovered through structural modifications of hydantoin antiandrogens. Several 4-(4-hydroxyphenyl)-N-arylhydantoins displayed partial agonism with nanomolar in vitro potency in transact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac608008905445d4f9b1a1f2414f5434
https://pubmed.ncbi.nlm.nih.gov/22897611
https://pubmed.ncbi.nlm.nih.gov/22897611
Functional studies of membrane-bound and purified human Hedgehog receptor Patched expressed in yeast
Autor:
Matthieu De Rivoyre, Olivier Joubert, Patrick Mollat, Bernard Pucci, Rony Nehmé, Damien Fleury, Isabelle Mus-Veteau, Michel Bidet, Martial Ruat, Ange Polidori
Publikováno v:
Biochimica et Biophysica Acta-Molecular Cell Research
Biochimica et Biophysica Acta-Molecular Cell Research, Elsevier, 2009, 1788 (9), pp.1813-21. ⟨10.1016/j.bbamem.2009.05.009⟩
Biochimica et Biophysica Acta-Molecular Cell Research, Elsevier, 2009, 1788 (9), pp.1813-21. ⟨10.1016/j.bbamem.2009.05.009⟩
International audience; The Sonic Hedgehog (Shh) signalling pathway plays an important role both in embryonic development and in adult stem cell function. Inappropriate regulation of this pathway is often due to dysfunction between two membrane recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d273b7deb9cce8222928ece2c51317
https://hal.archives-ouvertes.fr/hal-00408814
https://hal.archives-ouvertes.fr/hal-00408814
Autor:
Damien Fleury, Béatrice Vayssière, Robert Touitou, Georges Rawadi, Helene Lebhar, Corinne Gillard, Patrick Mollat
Publikováno v:
Protein expression and purification. 60(1)
Dickkopf-1 (Dkk1) protein is a secreted inhibitor of canonical Wnt signaling and modulates that pathway during embryonic development. It is also implicated in several diseases and hence Dkk1 is a potential target for therapeutic intervention. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8203e96c7f206ab22cf819749efcc70
https://pubmed.ncbi.nlm.nih.gov/18456511
https://pubmed.ncbi.nlm.nih.gov/18456511