Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Damien D Pearse"'
Autor:
Damien D Pearse, Mousumi Ghosh
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 7, Pp 1471-1472 (2022)
Externí odkaz:
https://doaj.org/article/d2a9815fc245461ba04fa7be996df70d
Autor:
Pascal J. Goldschmidt-Clermont, Aisha Khan, George Jimsheleishvili, Patricia Graham, Adriana Brooks, Risset Silvera, Alexander J.P. Goldschmidt, Damien D. Pearse, W. Dalton Dietrich, Allan D. Levi, James D. Guest
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 4, Pp 1207-1216 (2025)
Schwann cells are essential for the maintenance and function of motor neurons, axonal networks, and the neuromuscular junction. In amyotrophic lateral sclerosis, where motor neuron function is progressively lost, Schwann cell function may also be imp
Externí odkaz:
https://doaj.org/article/e5c269d416e04e22a6874077dceb1821
Publikováno v:
Neural Regeneration Research, Vol 10, Iss 10, Pp 1533-1536 (2015)
It has been controversial whether gender has any effect on recovery following spinal cord injury (SCI). Past experimental and clinical research aimed at addressing this subject has led to constrasting findings on whether females hold any advantage in
Externí odkaz:
https://doaj.org/article/0297197d52384b6c8041d5969a164dc4
Autor:
Mousumi eGhosh, Damien D Pearse
Publikováno v:
Frontiers in Neural Circuits, Vol 8 (2015)
Serotonin (5-HT), a monoamine neurotransmitter synthesized in various populations of brainstem neurons, plays an important role in modulating the activity of spinal networks involved in vertebrate locomotion. Following spinal cord injury (SCI) there
Externí odkaz:
https://doaj.org/article/b3afd5d69f304e0d94145c9ca641bd59
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118918 (2015)
Unlike CNS neurons in adult mammals, neurons in fish and embryonic mammals can regenerate their axons after injury. These divergent regenerative responses are in part mediated by the growth-associated expression of select transcription factors. The b
Externí odkaz:
https://doaj.org/article/f2f8515d1ff74296b237f645025d52d5
Autor:
Mousumi Ghosh, Damien D. Pearse
Publikováno v:
Cells, Vol 13, Iss 22, p 1834 (2024)
Microglia, the resident immune cells of the central nervous system (CNS), play a crucial role in maintaining neural homeostasis but can also contribute to disease and injury when this state is disrupted or conversely play a pivotal role in neurorepai
Externí odkaz:
https://doaj.org/article/e35c91237bf4489f8d8d85296e1a9a8a
Autor:
Joshua T Johnstone, Paul D Morton, Arumugam R Jayakumar, Andrea L Johnstone, Han Gao, Valerie Bracchi-Ricard, Damien D Pearse, Michael D Norenberg, John R Bethea
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80975 (2013)
Spinal cord injury is a debilitating neurological disorder that initiates a cascade of cellular events that result in a period of secondary damage that can last for months after the initial trauma. The ensuing outcome of these prolonged cellular pert
Externí odkaz:
https://doaj.org/article/e10a46523de94d9cbd4063806436dd81
Autor:
Mousumi Ghosh, Jinyoung Lee, Ashley N. Burke, Thomas A. Strong, Jacqueline Sagen, Damien D. Pearse
Publikováno v:
Cells, Vol 13, Iss 7, p 645 (2024)
Subacute spinal cord injury (SCI) displays a complex pathophysiology associated with pro-inflammation and ensuing tissue damage. Microglia, the resident innate immune cells of the CNS, in concert with infiltrating macrophages, are the primary contrib
Externí odkaz:
https://doaj.org/article/a56e06b1dd9046888ff4cb31fc90c495
Autor:
Risset Silvera, Adriana E Brooks, Anthony Diaz, Yelena Pressman, Aisha Khan, Gagani Athauda, Maxwell Donaldson, Damien D. Pearse, Mary Bartlett Bunge, Yee-Shuan Lee, S. Shelby Burks, Allan D. Levi, W. Dalton Dietrich, James D. Guest, Kim D Anderson, Patrick W. Wood
Publikováno v:
Journal of Neurosurgery: Spine. 36:135-144
OBJECTIVE Schwann cells (SCs) have been shown to play an essential role in axon regeneration in both peripheral nerve injuries (PNIs) and spinal cord injuries (SCIs). The transplantation of SCs as an adjunctive therapy is currently under investigatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62098f83351e25a393e5c2455f3ac874
https://doi.org/10.3171/2020.11.spine201433
https://doi.org/10.3171/2020.11.spine201433
Autor:
Pascal J. Goldschmidt-Clermont, Aisha Khan, James D. Guest, George Jimsheleishvili, Patricia Graham, Adriana Brooks, Risset Silvera, Alexander J.P. Goldschmidt, Damien D. Pearse, W. Dalton Dietrich, Robert Brown, Allan D. Levi
SummaryAmyotrophic Lateral Sclerosis (ALS) is a terminal condition with accelerated loss of motor neurons (MN), resulting in the progressive paralysis of affected patients. ALS is either sporadic (90%) or genetically transmitted (10%) and affects cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7e7dbdaa4d9a6dc197ad2074897c99d
https://doi.org/10.1101/2023.01.18.23284378
https://doi.org/10.1101/2023.01.18.23284378
