Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Damien D Pearse"'
Autor:
Pascal J. Goldschmidt-Clermont, Aisha Khan, George Jimsheleishvili, Patricia Graham, Adriana Brooks, Risset Silvera, Alexander J.P. Goldschmidt, Damien D. Pearse, W. Dalton Dietrich, Allan D. Levi, James D. Guest
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 4, Pp 1207-1216 (2025)
Schwann cells are essential for the maintenance and function of motor neurons, axonal networks, and the neuromuscular junction. In amyotrophic lateral sclerosis, where motor neuron function is progressively lost, Schwann cell function may also be imp
Externí odkaz:
https://doaj.org/article/e5c269d416e04e22a6874077dceb1821
Autor:
Mousumi Ghosh, Damien D. Pearse
Publikováno v:
Cells, Vol 13, Iss 22, p 1834 (2024)
Microglia, the resident immune cells of the central nervous system (CNS), play a crucial role in maintaining neural homeostasis but can also contribute to disease and injury when this state is disrupted or conversely play a pivotal role in neurorepai
Externí odkaz:
https://doaj.org/article/e35c91237bf4489f8d8d85296e1a9a8a
Autor:
Mousumi Ghosh, Jinyoung Lee, Ashley N. Burke, Thomas A. Strong, Jacqueline Sagen, Damien D. Pearse
Publikováno v:
Cells, Vol 13, Iss 7, p 645 (2024)
Subacute spinal cord injury (SCI) displays a complex pathophysiology associated with pro-inflammation and ensuing tissue damage. Microglia, the resident innate immune cells of the CNS, in concert with infiltrating macrophages, are the primary contrib
Externí odkaz:
https://doaj.org/article/a56e06b1dd9046888ff4cb31fc90c495
Autor:
Damien D Pearse, Mousumi Ghosh
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 7, Pp 1471-1472 (2022)
Externí odkaz:
https://doaj.org/article/d2a9815fc245461ba04fa7be996df70d
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1241 (2022)
Multiple Sclerosis (MS) is a chronic CNS autoimmune disease characterized by immune-mediated demyelination, axon loss, and disability. Dysregulation of transglutaminase-2 (TG2) has been implicated in disease initiation and progression. Herein, TG2 ex
Externí odkaz:
https://doaj.org/article/08e5e3b7c8c34aa29819d7cd7af226ca
Autor:
Erin M. Wolfe, BS, Sydney A. Mathis, BS, Natalia de la Oliva Munoz, PhD, Daisy I. Gonzalez, BS, Steven A. Ovadia, MD, Prakash J. Mathew, MD, Damien D. Pearse, PhD, Martin Oudega, PhD, Zubin J. Panthaki
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 8, Iss 4S, Pp 133-133 (2020)
Externí odkaz:
https://doaj.org/article/fed461a2409442b4923451d4b2fb60ae
Autor:
Risset Silvera, Adriana E Brooks, Anthony Diaz, Yelena Pressman, Aisha Khan, Gagani Athauda, Maxwell Donaldson, Damien D. Pearse, Mary Bartlett Bunge, Yee-Shuan Lee, S. Shelby Burks, Allan D. Levi, W. Dalton Dietrich, James D. Guest, Kim D Anderson, Patrick W. Wood
Publikováno v:
Journal of Neurosurgery: Spine. 36:135-144
OBJECTIVE Schwann cells (SCs) have been shown to play an essential role in axon regeneration in both peripheral nerve injuries (PNIs) and spinal cord injuries (SCIs). The transplantation of SCs as an adjunctive therapy is currently under investigatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62098f83351e25a393e5c2455f3ac874
https://doi.org/10.3171/2020.11.spine201433
https://doi.org/10.3171/2020.11.spine201433
Autor:
Pascal J. Goldschmidt-Clermont, Aisha Khan, James D. Guest, George Jimsheleishvili, Patricia Graham, Adriana Brooks, Risset Silvera, Alexander J.P. Goldschmidt, Damien D. Pearse, W. Dalton Dietrich, Robert Brown, Allan D. Levi
SummaryAmyotrophic Lateral Sclerosis (ALS) is a terminal condition with accelerated loss of motor neurons (MN), resulting in the progressive paralysis of affected patients. ALS is either sporadic (90%) or genetically transmitted (10%) and affects cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7e7dbdaa4d9a6dc197ad2074897c99d
https://doi.org/10.1101/2023.01.18.23284378
https://doi.org/10.1101/2023.01.18.23284378
Publikováno v:
Neural Regeneration Research, Vol 10, Iss 10, Pp 1533-1536 (2015)
It has been controversial whether gender has any effect on recovery following spinal cord injury (SCI). Past experimental and clinical research aimed at addressing this subject has led to constrasting findings on whether females hold any advantage in
Externí odkaz:
https://doaj.org/article/0297197d52384b6c8041d5969a164dc4
Publikováno v:
Neuroscience. 461:140-154
Transglutiminase-2 (TG2) is a multifunctional enzyme that has been implicated in the pathogenesis of experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS) using global knockout mice and TG2 selective inhibitors. Previous studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a3e9b410495749f7d1e03d6a108ce7
https://doi.org/10.1016/j.neuroscience.2020.11.034
https://doi.org/10.1016/j.neuroscience.2020.11.034