Aqueous 1,3-dipolar cycloadditions promoted by copper nanoparticles in polydiacetylene micelles

Autor: Frédéric Miserque, Damien Clarisse, Praveen Prakash, Eric Doris, Edmond Gravel, Valérie Geertsen

Publikováno v: Green Chemistry
Green Chemistry, Royal Society of Chemistry, 2017, 19, pp.3112-3115. ⟨10.1039/C7GC01017F⟩
Green Chemistry, 2017, 19, pp.3112-3115. ⟨10.1039/C7GC01017F⟩

International audience; A novel colloidal catalyst was developed through the encapsulation of cuprous oxide nanoparticles in polydiacetylene micelles. The Cu-based catalyst was applied to the Huisgen cycloaddition reaction in fully aqueous medium. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdbb3fa11fd8321a11060d3a5b490445
https://hal-cea.archives-ouvertes.fr/cea-01523476

Stable and compact zwitterionic polydiacetylene micelles with tumor-targeting properties

Autor: Damien Clarisse, Eric Doris, Ioanna Theodorou, Edmond Gravel, Frédéric Ducongé, Anaëlle Doerflinger, Benoît Lelandais, Parambath Anilkumar

Publikováno v: Chemical Communications
Chemical Communications, Royal Society of Chemistry, 2015, 51 (80), pp.14937-14940. ⟨10.1039/C5CC05333A⟩

Compact polymerized polydiacetylene-micelles with “stealth” zwitterionic surface coating were assembled and tested in a murine xenograft model of breast cancer. In vivo fluorescence imaging indicated accumulation in the tumor area and histologica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ce05bb96f2409fc2990069b717f9e4
https://hal.archives-ouvertes.fr/hal-02626501

Application of prins cyclization to the total synthesis of (+)-decytospolides A and B

Autor: Fabienne Fache, Damien Clarisse

Publikováno v: Tetrahedron Letters
Tetrahedron Letters, Elsevier, 2014, 55, pp.2221-2222

(+)-Decytospolides A and B, natural products containing the tetrahydropyran skeleton, were synthesized via Prins cyclization as the key step.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1597876d70d52b887e26e0b8abb2842
https://hal.archives-ouvertes.fr/hal-01150917

Hexafluoroisopropanol: a powerful solvent for the hydrogenation of indole derivatives. Selective access to tetrahydroindoles or cis-fused octahydroindoles

Autor: Bernard Fenet, Fabienne Fache, Damien Clarisse

Publikováno v: Organicbiomolecular chemistry. 10(32)

Pd/C in HFIP was used to hydrogenate indole derivatives under relatively mild conditions, leading to potential synthetic intermediates of bioactive compounds. Depending on their substitution, tetrahydroindoles or octahydroindoles could selectively be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca68bbfa988fba48c9db1be795f9561d
https://pubmed.ncbi.nlm.nih.gov/22782846

Green chemistry : solvent and metal-free prins cyclization. Application to sequential reactions

Autor: Olivier Piva, Damien Clarisse, Fabienne Fache, Béatrice Pelotier

Publikováno v: Journal of the Chemical Society, Chemical Communications
Journal of the Chemical Society, Chemical Communications, Royal Society of Chemistry, 2011, 48, pp.157-159. ⟨10.1002/chem.201102462⟩
Chemical Communications
Chemical Communications, Royal Society of Chemistry, 2012, 48 (1), pp.157-9. ⟨10.1039/c1cc16501a⟩

International audience; Prins cyclization between a homoallylic alcohol and an aldehyde, promoted by trimethylsilyl halide, afforded 4-halo-tetrahydropyrans with good to excellent yields. Thanks to the absence of the solvent and metal, the THP thus o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fb574ee087e102bfeece4ed0c687dde
https://hal.archives-ouvertes.fr/hal-01313128