Effect of sirolimus on muscle in inclusion body myositis observed with magnetic resonance imaging and spectroscopy

Autor: Harmen Reyngoudt, Pierre‐Yves Baudin, Ericky Caldas de Almeida Araújo, Damien Bachasson, Jean‐Marc Boisserie, Kubéraka Mariampillai, Mélanie Annoussamy, Yves Allenbach, Jean‐Yves Hogrel, Pierre G. Carlier, Benjamin Marty, Olivier Benveniste

Publikováno v: Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 3, Pp 1108-1120 (2024)

Abstract Background Finding sensitive clinical outcome measures has become crucial in natural history studies and therapeutic trials of neuromuscular disorders. Here, we focus on 1‐year longitudinal data from quantitative magnetic resonance imaging

Externí odkaz: https://doaj.org/article/0ff63e8cc1324c1da8a712afd1ed760d

Non-invasive assessment of skeletal muscle fibrosis in mice using nuclear magnetic resonance imaging and ultrasound shear wave elastography

Autor: Aurea B. Martins-Bach, Damien Bachasson, Ericky C. A. Araujo, Lucas Soustelle, Paulo Loureiro de Sousa, Yves Fromes, Pierre G. Carlier

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)

Abstract Fibrosis is a key pathological feature in muscle disorders, but its quantification mainly relies on histological and biochemical assays. Muscle fibrosis most frequently is entangled with other pathological processes, as cell membrane lesions

Externí odkaz: https://doaj.org/article/3ee33b1ee6e54e01b6a86cda27b65658

Quadriceps and respiratory muscle fatigue following high-intensity cycling in COPD patients.

Autor: Damien Bachasson, Bernard Wuyam, Jean-Louis Pepin, Renaud Tamisier, Patrick Levy, Samuel Verges

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e83432 (2013)

Exercise intolerance in COPD seems to combine abnormal ventilatory mechanics, impaired O2 transport and skeletal muscle dysfunction. However their relative contribution and their influence on symptoms reported by patients remain to be clarified. In o

Externí odkaz: https://doaj.org/article/e588771b04124eed9d8ee5544b482a75

Poor Correlation between Diaphragm Thickening Fraction and Transdiaphragmatic Pressure in Mechanically Ventilated Patients and Healthy Subjects

Autor: Thomas Poulard, Jean-Luc Gennisson, Damien Bachasson, Martin Dres, Alexandre Demoule, Marie-Cécile Niérat, Jean-Yves Hogrel, Quentin Fossé

Publikováno v: Anesthesiology
Anesthesiology, Lippincott, Williams & Wilkins, 2022, 136 (1), pp.162-175. ⟨10.1097/ALN.0000000000004042⟩
Anesthesiology, 2022, 136 (1), pp.162-175. ⟨10.1097/ALN.0000000000004042⟩

Background The relationship between the diaphragm thickening fraction and the transdiaphragmatic pressure, the reference method to evaluate the diaphragm function, has not been clearly established. This study investigated the global and intraindividu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc41f0b767d291059709c4fe9015c0ea
https://doi.org/10.1097/aln.0000000000004042

Diaphragm shear modulus reflects transdiaphragmatic pressure during isovolumetric inspiratory efforts and ventilation against inspiratory loading

Autor: Thomas Similowski, Damien Bachasson, Jean-Yves Hogrel, Marie-Cécile Niérat, Martin Dres, Jean-Luc Gennisson, Jonne Doorduin

Publikováno v: Journal of Applied Physiology, 126, 3, pp. 699-707
Journal of Applied Physiology, 126, 699-707
Journal of Applied Physiology
Journal of Applied Physiology, 2019, 126 (3), pp.699-707. ⟨10.1152/japplphysiol.01060.2018⟩

The reference method for the assessment of diaphragm function relies on the measurement of transdiaphragmatic pressure (Pdi). Local muscle stiffness measured using ultrafast shear wave elastography (SWE) provides reliable estimates of muscle force in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c3411dd565b5733e9ae242dd4223be
https://hdl.handle.net/2066/202573