Výsledky vyhledávání - "Damien, Reita"

Akademický článek

Fulminant leptomeningeal disease diagnosed as comutant H3F3A and FGFR diffuse midline glioma

Autor: Larysa Benistant, Damien Reita, Maleka Schenck, Vincent Castelain, Hélène Cebula, Benoît Lhermitte, Laura Bender

Publikováno v: Annals of Clinical and Translational Neurology, Vol 11, Iss 11, Pp 3037-3041 (2024)

Abstract Diffuse midline gliomas present a particularly intricate and challenging clinical scenario. This rare case involves a patient with comutant H3F3A and FGFR diffuse midline glioma with a clinical presentation of fulminant leptomeningitis. A 22

Externí odkaz: https://doaj.org/article/2931e7a86ede40d0912b2c90aa58b40b

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Akademický článek

Clinical impact of large genomic explorations at diagnosis in 198 pediatric solid tumors: a monocentric study aiming practical feasibility of precision oncology

Autor: Juliette Simon, Damien Reita, Eric Guerin, Benoit Lhermitte, Noelle Weingertner, François Lefebvre, Marie Karanian, Julien Masliah-Planchon, Veronique Lindner, Alina Onea, Sarah Jannier, Alexandra Salmon, Guillaume Bergthold, Florence Vincent, Marlène Deschuyter, Marie-Odile Barbaza, Natacha Entz-Werlé

Publikováno v: BMC Cancer, Vol 24, Iss 1, Pp 1-18 (2024)

Abstract Introduction Faced to the growing development of collecting systematic molecular analyses in relapsed pediatric cancers to transform their targeted matched therapies, this study aimed to assess the clinical and therapeutic indications of sys

Externí odkaz: https://doaj.org/article/fd4aae2496a942ca8d74a1c96e7ff44d

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All pineal tumors expressing germ cell tumor markers are not necessarily germ cell tumors: histopathological and molecular study of a midline primary intracranial sarcoma DICER1-mutant

Autor: Thibaut Wolf, Andres Hugo Coca, Noelle Weingertner, Marie Pierre Chenard, Alexandra Meurgey, Damien Reita, Erwan Pencreach, Pascale Varlet, Natacha Entz-Werlé, Benoît Lhermitte

Publikováno v: Virchows Archiv : an international journal of pathology.

Primary intracranial sarcoma DICER1-mutant is a rare and newly recognized tumor type introduced in the 2021 WHO Classification of Central Nervous System Tumors. It is defined as a spindle cell sarcoma dysplaying eosinophilic intracytoplasmic globules

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7ee675c4f0b0191296ff2749b74fa1
https://pubmed.ncbi.nlm.nih.gov/36307659

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Glioblastoma Metabolism: Insights and Therapeutic Strategies

Autor: Chloé Bernhard, Damien Reita, Sophie Martin, Natacha Entz-Werle, Monique Dontenwill

Publikováno v: International Journal of Molecular Sciences. 24:9137

Tumor metabolism is emerging as a potential target for cancer therapies. This new approach holds particular promise for the treatment of glioblastoma, a highly lethal brain tumor that is resistant to conventional treatments, for which improving thera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dbc00ebdb75f5adfc657ba3e485337bd
https://doi.org/10.3390/ijms24119137

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Temozolomide-Acquired Resistance Is Associated with Modulation of the Integrin Repertoire in Glioblastoma, Impact of α5β1 Integrin

Autor: Saidu Sani, Nikita Pallaoro, Mélissa Messe, Chloé Bernhard, Nelly Etienne-Selloum, Horst Kessler, Luciana Marinelli, Natacha Entz-Werle, Sophie Foppolo, Sophie Martin, Damien Reita, Monique Dontenwill

Publikováno v: Cancers, Vol 14, Iss 369, p 369 (2022)
Cancers; Volume 14; Issue 2; Pages: 369
Cancers

Simple Summary Glioblastomas are the deadliest brain tumours. The standard of care associates surgery, radio- and chemotherapy with Temozolomide as the reference drug. Despite this treatment, most of the tumours recur. The characterization of resista

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ade05d13a586e74a91c1f978d9dcce55
http://hdl.handle.net/11588/877408

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p16 Immunohistochemical Expression as a Surrogate Assessment of CDKN2A Alteration in Gliomas Leading to Prognostic Significances

Autor: Lucas Geyer, Thibaut Wolf, Marie-Pierre Chenard, Helene Cebula, Roland Schott, Georges Noel, Eric Guerin, Erwan Pencreach, Damien Reita, Natacha Entz-Werlé, Benoît Lhermitte

Publikováno v: Cancers
Volume 15
Issue 5
Pages: 1512

CDKN2A is a tumor suppressor gene encoding the p16 protein, a key regulator of the cell cycle. CDKN2A homozygous deletion is a central prognostic factor for numerous tumors and can be detected by several techniques. This study aims to evaluate the ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e659e8f14343831578ce99f17a22b150
https://doi.org/10.3390/cancers15051512

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Molecular Heterogeneity in BRAF-Mutant Gliomas: Diagnostic, Prognostic, and Therapeutic Implications

Autor: Benoit Lhermitte, Thibaut Wolf, Marie Pierre Chenard, Andres Coca, Julien Todeschi, François Proust, Edouard Hirsch, Roland Schott, Georges Noel, Eric Guerin, Damien Reita, Agathe Chammas, Alexandra Salmon, Sophie Martin, Monique Dontenwill, Natacha Entz-Werlé

Publikováno v: Cancers. 15:1268

Over the last few decades, deciphering the alteration of molecular pathways in brain tumors has led to impressive changes in diagnostic refinement. Among the molecular abnormalities triggering and/or driving gliomas, alterations in the MAPK pathway r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9ec0ab8149361ec47db2886e9657c6d
https://doi.org/10.3390/cancers15041268

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Direct Targeting

Autor: Damien, Reita, Lucile, Pabst, Erwan, Pencreach, Eric, Guérin, Laurent, Dano, Valérie, Rimelen, Anne-Claire, Voegeli, Laurent, Vallat, Céline, Mascaux, Michèle, Beau-Faller

Publikováno v: Cancers. 14(5)

KRAS is the most frequently mutated oncogene in non-small cell lung cancers (NSCLC), with a frequency of around 30%, and encoding a GTPAse that cycles between active form (GTP-bound) to inactive form (GDP-bound). The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2bfbda120bd62d2d5af0694de12ccfe2
https://pubmed.ncbi.nlm.nih.gov/35267628

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Molecular Mechanism of EGFR-TKI Resistance in

Autor: Damien, Reita, Lucile, Pabst, Erwan, Pencreach, Eric, Guérin, Laurent, Dano, Valérie, Rimelen, Anne-Claire, Voegeli, Laurent, Vallat, Céline, Mascaux, Michèle, Beau-Faller

Publikováno v: Cancers

Simple Summary Non-small cell lung cancer (NSCLC) is the most common cancer in the world. For common EGFR mutations, treatment is based on different inhibitors. Despite the excellent disease control with inhibitors, acquired resistance inevitably occ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2d92d02af02d0d3b8a2e5e548421afa0
https://pubmed.ncbi.nlm.nih.gov/34638411

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LGG-16. Retrospective and integrative analyses of molecular characteristics and their specific imaging parameters in pediatric grade 1 gliomas

Autor: Marie Courant, Benoit Lhermitte, Eric Guerin, Agathe Chammas, Damien Reita, Consuelo Sebastia, Valérie Douzal, Flaviu Gabor, Alexandra Salmon, Julien Todeschi, Andres Hugo Coca, Florence Vincent, Natacha Entz-Werlé

Publikováno v: Neuro-Oncology. 24:i91-i91

Pediatric low-grade gliomas (PLGG) are the most common brain tumors diagnosed during childhood and represent a heterogeneous group associating variable molecular abnormalities. To go further and develop specific statistical patterns integrating altog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e073b6f4cae1cc4433b3205d62a37ea3
https://doi.org/10.1093/neuonc/noac079.331

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