Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Damien, Maggiorani"'
Autor:
Damien Maggiorani, Oanh Le, Véronique Lisi, Séverine Landais, Gaël Moquin-Beaudry, Vincent Philippe Lavallée, Hélène Decaluwe, Christian Beauséjour
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The potential of immune checkpoint inhibitors (ICI) may be limited in situations where immune cell fitness is impaired. Here, we show that the efficacy of cancer immunotherapies is compromised by the accumulation of senescent cells in mice a
Externí odkaz:
https://doaj.org/article/6176530a4d9a475d942f002aa1f6fc5f
Autor:
Talita C. Conte, Gilberto Duran-Bishop, Zakaria Orfi, Inès Mokhtari, Alyson Deprez, Isabelle Côté, Thomas Molina, Tae-Yeon Kim, Lydia Tellier, Marie-Pier Roussel, Damien Maggiorani, Basma Benabdallah, Severine Leclerc, Lara Feulner, Ornella Pellerito, Jean Mathieu, Gregor Andelfinger, Cynthia Gagnon, Christian Beauséjour, Serge McGraw, Elise Duchesne, Nicolas A. Dumont
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Muscle stem cells, the engine of muscle repair, are affected in myotonic dystrophy type 1 (DM1); however, the underlying molecular mechanism and the impact on the disease severity are still elusive. Here, we show using patients’ samples th
Externí odkaz:
https://doaj.org/article/72d4142afc3647a1818a01b7490a64b2
Publikováno v:
Cells, Vol 10, Iss 7, p 1568 (2021)
Cancer incidence increases drastically with age. Of the many possible reasons for this, there is the accumulation of senescent cells in tissues and the loss of function and proliferation potential of immune cells, often referred to as immuno-senescen
Externí odkaz:
https://doaj.org/article/9ec784da72ee4e5dbf4507d5a434ff17
Autor:
Hélène Martini, Lise Lefevre, Sylvain Sayir, Romain Itier, Damien Maggiorani, Marianne Dutaur, Dimitri J. Marsal, Jérôme Roncalli, Nathalie Pizzinat, Daniel Cussac, Angelo Parini, Jeanne Mialet-Perez, Victorine Douin-Echinard
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2245 (2021)
Accumulation of senescent cells in tissues during normal or accelerated aging has been shown to be detrimental and to favor the outcomes of age-related diseases such as heart failure (HF). We have previously shown that oxidative stress dependent on m
Externí odkaz:
https://doaj.org/article/124b896158324b4189a5f11323af1e79
Autor:
Mohammad Ali Mohammad Nezhady, Gael Cagnone, Emmanuel Bajon, Prabhas Chaudhari, Monir Modaresinejad, Pierre Hardy, Damien Maggiorani, Christiane Quiniou, Jean-Sébastien Joyal, Christian Beauséjour, Sylvain Chemtob
The involvement of G-Protein-Coupled Receptors’ (GPCR) location bias in diverse cellular functions and their misregulation in pathology is an underexplored territory. HCAR1, a GPCR for lactate is linked to cancer progression, mainly due to Warburg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3303a1c39a26ca883cd7fbcdfcb297b0
https://doi.org/10.1101/2022.07.25.501445
https://doi.org/10.1101/2022.07.25.501445
Autor:
Talita C. Conte, Gilberto Duran-Bishop, Zakaria Orfi, Inès Mokhtari, Alyson Deprez, Marie-Pier Roussel, Isabelle Côté, Ornella Pellerito, Damien Maggiorani, Basma Benabdallah, Severine Leclerc, Lara Feulner, Jean Mathieu, Cynthia Gagnon, Gregor Andelfinger, Christian Beauséjour, Serge McGraw, Elise Duchesne, Nicolas A. Dumont
Muscle weakness and atrophy are clinical hallmarks of myotonic dystrophy type 1 (DM1). Muscle stem cells, which contribute to skeletal muscle growth and repair, are also affected in this disease. However, the molecular mechanisms leading to this defe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dad73f6e36074aa0da3fb507bf7388fd
https://doi.org/10.1101/2022.06.22.497227
https://doi.org/10.1101/2022.06.22.497227
Autor:
Damien Maggiorani, Romain Dissard, Marcy Belloy, Jean-Sébastien Saulnier-Blache, Audrey Casemayou, Laure Ducasse, Sandra Grès, Julie Bellière, Cécile Caubet, Jean-Loup Bascands, Joost P Schanstra, Bénédicte Buffin-Meyer
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131416 (2015)
Tubular epithelial cells in the kidney are continuously exposed to urinary fluid shear stress (FSS) generated by urine movement and recent in vitro studies suggest that changes of FSS could contribute to kidney injury. However it is unclear whether F
Externí odkaz:
https://doaj.org/article/c8c6f9ff19c84cd4868c5ba073a72f0d
Publikováno v:
Cells, Vol 10, Iss 1568, p 1568 (2021)
Cells
Cells
Cancer incidence increases drastically with age. Of the many possible reasons for this, there is the accumulation of senescent cells in tissues and the loss of function and proliferation potential of immune cells, often referred to as immuno-senescen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac29b846b7dd8cb154cd262f75041b7
https://www.mdpi.com/2073-4409/10/7/1568
https://www.mdpi.com/2073-4409/10/7/1568
Autor:
Dorothée Dal Soglio, Damien Maggiorani, Yuanyi Li, Benjamin Ellezam, Chloé Colas, Massimiliano Paganelli, Basma F. Benabdallah, Gaël Moquin-Beaudry, Elie Haddad, Marie-Agnès M’Callum, Jean V. Guimond, Claudia Raggi, Christian Beauséjour, Oanh Le
Modeling the tumor-immune cell interactions in humanized mice is complex and limits drug development. Here, we generated easily accessible tumor models by transforming either primary skin fibroblasts or iPSC-derived cell lines injected in immune-defi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd291d458552ccbe908a17788857d3f3
https://doi.org/10.1101/2021.04.02.437733
https://doi.org/10.1101/2021.04.02.437733
Autor:
Lise, Lefèvre, Jason S, Iacovoni, Hélène, Martini, Julie, Bellière, Damien, Maggiorani, Marianne, Dutaur, Dimitri J, Marsal, Pauline, Decaunes, Nathalie, Pizzinat, Jeanne, Mialet-Perez, Daniel, Cussac, Angelo, Parini, Victorine, Douin-Echinard
Publikováno v:
Cellular and Molecular Life Sciences
The incidence of disorders associated with low inflammatory state, such as chronic kidney disease, increases in the elderly. The accumulation of senescent cells during aging and the senescence-associated secretory phenotype, which leads to inflammagi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::378284467ecb9a7f24351fc49b650f22
https://pubmed.ncbi.nlm.nih.gov/33313981
https://pubmed.ncbi.nlm.nih.gov/33313981