Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Damien, Calay"'
Autor:
Nicola N Lynskey, Mark Reglinski, Damien Calay, Matthew K Siggins, Justin C Mason, Marina Botto, Shiranee Sriskandan
Publikováno v:
PLoS Pathogens, Vol 13, Iss 8, p e1006493 (2017)
The complement cascade is crucial for clearance and control of invading pathogens, and as such is a key target for pathogen mediated host modulation. C3 is the central molecule of the complement cascade, and plays a vital role in opsonization of bact
Externí odkaz:
https://doaj.org/article/7031e2a0cadc406fa19911befda17da0
Autor:
Shanjid Shiplu, Sabrina Gies, Damien Calay, Jan Hendrickx, Nihan Ozturk, Undraga Schagdarsurengin, Temuujin Dansranjavin, Catherine Creppe
Publikováno v:
Development. 148
Sperm histones represent an essential part of the paternally transmitted epigenome, but uncertainty exists about the role of those remaining in non-coding and repetitive DNA. We therefore analyzed the genome-wide distribution of the heterochromatic m
Autor:
Caroline P.D. Wheeler-Jones, A. Seneviratne, Clare C. Thornton, Dorian O. Haskard, Andrea Bauer, Alex H. Schönthal, Damien Calay, Allan P. Kiprianos, Joseph J. Boyle, Justin C Mason, Marie Lang, Fahad Al-Rashed
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Scientific Reports (Nature)
Scientific Reports
Scientific Reports (Nature)
Scientific Reports
Although concern remains about the athero-thrombotic risk posed by cyclo-oxygenase (COX)-2-selective inhibitors, recent data implicates rofecoxib, while celecoxib appears equivalent to NSAIDs naproxen and ibuprofen. We investigated the hypothesis tha
Autor:
Damien Calay, C. Thornton, A. Kiprianos, Anusha N. Seneviratne, Dorian O. Haskard, Joseph J. Boyle, F. Alrashed, A Bauer, Justin C. Mason
Publikováno v:
Poster Presentations.
Background Although concern remains about the athero-thrombotic risk posed by COX-2-selective inhibitors (COXIBs), the recent PRECISION trial demonstrated non-inferiority of moderate dose celecoxib when compared to naproxen and ibuprofen with respect
Autor:
Damien Calay, Justin C. Mason
Publikováno v:
Antioxidants & Redox Signaling. 20:1789-1809
Heme oxygenases (HO-1 and HO-2) catalyze the degradation of the pro-oxidant heme into carbon monoxide (CO), iron, and biliverdin, which is subsequently converted to bilirubin. In the vasculature, particular interest has focused on antioxidant and ant
Autor:
Damien Calay, Victor Pallarès, Lídia Cedó, Lluís Arola, Martine Raes, Mayte Blay, Montserrat Pinent, Anna Ardévol, Anna Castell-Auví
Publikováno v:
Nutrition. 28:447-457
Objective Macrophages play an important role in immunogenic challenges and can aggravate and propagate local inflammation. Nuclear factor-kappa B (NF-κB) and activator protein 1 pathways can regulate these inflammatory processes by modulating expres
Autor:
Lídia Cedó, Mayte Blay, Montserrat Pinent, Anna Castell-Auví, Lluís Arola, Anna Ardévol, Victor Pallarès, Martine Raes, Damien Calay
Publikováno v:
British Journal of Nutrition. 108:1562-1573
Macrophages play an important role in immunogenic challenges by producing reactive oxygen species, NO and proinflammatory cytokines that can aggravate and propagate local inflammation. Multiple mechanisms regulate these inflammatory processes. NF-κB
Autor:
Laurine, Mattart, Damien, Calay, Dorothy, Simon, Laura, Roebroek, Laura, Roebroeck, Ludmilla, Caesens-Koenig, Martine, Van Steenbrugge, Virginie, Tevel, Carine, Michiels, Thierry, Arnould, Karim Zouaoui, Boudjeltia, Martine, Raes
Publikováno v:
Cellular Signalling. 24(1):199-213
Endothelial dysfunction is associated with the formation of peroxynitrite, described to be toxic. Recent data also suggests that peroxynitrite is able to activate the protective Nrf2 pathway and/or the unfolded protein response (UPR). The aim of our
Autor:
Martine Raes, Jean Nève, Jean-Claude Michalski, Nicole Moguilevsky, Pierre Van Antwerpen, Cédric Delporte, Damien Calay, Valegh Faid, Marie-Christine Slomianny, Alexandre Rousseau, Luc Vanhamme, Karim Zouaoui Boudjeltia, Michel Vanhaeverbeek, Christian Obinger, Paul G. Furtmüller
Publikováno v:
Journal of Biological Chemistry. 285:16351-16359
The involvement of myeloperoxidase (MPO) in various inflammatory conditions has been the scope of many recent studies. Besides its well studied catalytic activity, the role of its overall structure and glycosylation pattern in biological function is
Autor:
Sylviane Lambert, Dina Vind-Kezunovic, Damien Calay, Robert Gniadecki, Yves Poumay, Aurelie Frankart
Publikováno v:
Journal of Investigative Dermatology. 130:1136-1145
Lipid rafts are cholesterol-rich plasma membrane domains that regulate signal transduction. Because our earlier work indicated that raft disruption inhibited proliferation and caused cell death, we investigated here the role of membrane cholesterol,