Výsledky vyhledávání - "Damiano Turini"

Characterization of kinin receptors in human cultured detrusor smooth muscle cells

Autor: Paola Cucchi, Francesca Bellucci, Paolo Santicioli, Damiano Turini, Massimo Lazzeri, Stefania Meini

Publikováno v: British Journal of Pharmacology. 150:192-199

Background and purpose: Kinins have an important role in inflammatory cystitis and in animal pathophysiological models, by acting on epithelium, fibroblasts, sensory innervation and smooth muscle. The aim of this study was to characterize the recepto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85aa85f9e47d28c774d3db40cfe14c69
https://doi.org/10.1038/sj.bjp.0706976

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Urodynamic effects of intravesical nociceptin/orphanin FQ in neurogenic detrusor overactivity: a randomized, placebo-controlled, double-blind study

Autor: Domenico Regoli, Michele Spinelli, Damiano Turini, Sandro Sandri, Severo Salvadori, Massimo Lazzeri, Remo Guerrini, Patrizia Beneforti, Girolamo Calo

Publikováno v: Urology. 61:946-950

To evaluate the acute urodynamic effects of the neuropeptide nociceptin/orphanin FQ (N/OFQ) in a selected group of patients with neurogenic detrusor overactivity incontinence in a randomized, placebo-controlled, double-blind study.The study involved

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445f66b7b830d506da1b4749f3e8f331
https://doi.org/10.1016/s0090-4295(02)02587-6

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Tachykinin NK1 and NK2 receptors mediate inhibitory vs excitatory motor responses in human isolated corpus cavernosum and spongiosum

Autor: Guido Barbagli, Enzo Palminteri, Massimo Lazzeri, Riccardo Patacchini, Carlo Alberto Maggi, Damiano Turini

Publikováno v: British Journal of Pharmacology. 135:1351-1354

Motor effects produced by tachykinins were studied in human isolated corpus spongiosum and cavernosum. In quiescent preparations neurokinin A caused potent contractions (pD2=8.3 – 7.9 respectively) prevented by the NK2 receptor-selective antagonist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d15c60ed7ae499fba549b03e415618b6
https://doi.org/10.1038/sj.bjp.0704650

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URODYNAMIC AND CLINICAL EVIDENCE OF ACUTE INHIBITORY EFFECTS OF INTRAVESICAL NOCICEPTIN/ORPHANIN FQ ON DETRUSOR OVERACTIVITY IN HUMANS: A PILOT STUDY

Autor: Damiano Turini, Massimo Lazzeri, Remo Guerrini, Patrizia Beneforti, Girolamo Cal`O, Domenico Regoli, Sandro Sandri, A. Zanollo, Michele Spinelli

Publikováno v: Scopus-Elsevier

Purpose: Management of neurogenic incontinence is complex and available treatments are not satisfactory. Nociceptin/orphanin FQ, a recently discovered neuropeptide, has been reported to inhibit the voiding reflex in the rat. These experimental result

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a14e43c5308fadb2c6fc4ba97329ad
https://doi.org/10.1016/s0022-5347(05)65541-3

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Excitatory motor and electrical effects produced by tachykinins in the human and guinea-pig isolated ureter and guinea-pig renal pelvis

Autor: Carlo Alberto Maggi, Vladimir P. Zagorodnyuk, Paolo Santicioli, Riccardo Patacchini, Massimo Lazzeri, Damiano Turini

Publikováno v: British Journal of Pharmacology. 125:987-996

1 In isolated tissue experiments, neurokinin A (NKA) produced concentration-dependent contraction of human and guinea-pig ureter (pD2=6.7 and 7.2, respectively); an effect greatly reduced (>80% inhibition) by the tachykinin NK2 receptor-selective ant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::416bd385129d24a96399ba0f6d600453
https://doi.org/10.1038/sj.bjp.0702147

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Intravesical Resiniferatoxin for the Treatment of Detrusor Hyperreflexia Refractory to Capsaicin in Patients with Chronic Spinal Cord Diseases

Autor: A. Zanollo, Patrizia Beneforti, Massimo Lazzeri, Michele Spinelli, Damiano Turini

Publikováno v: Scandinavian Journal of Urology and Nephrology. 32:331-334

OBJECTIVE Resiniferatoxin (RTX), a substance isolated from some species of Euphorbia, a cactus-like plant, shows pharmacological effects similar to those of capsaicin. We have studied the possibility of treating detrusor hyperreflexia refractory to i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9ba6a440f5711ebd9030fc857250c44
https://doi.org/10.1080/003655998750015287

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URODYNAMIC EFFECTS OF INTRAVESICAL RESINIFERATOXIN IN HUMANS: PRELIMINARY RESULTS IN STABLE AND UNSTABLE DETRUSOR

Autor: Patrizia Beneforti, Massimo Lazzeri, Damiano Turini

Publikováno v: Journal of Urology. 158:2093-2096

Purpose: Resiniferatoxin, a substance isolated from some species of euphorbia, a cactus-like plant, presents pharmacological effects similar to those of capsaicin. We studied the urodynamic effects of intravesical resiniferatoxin* *RBI Research Bioch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1da39312958700bc5ff9a151a5be751c
https://doi.org/10.1016/s0022-5347(01)68164-3

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Tachykinin NK1 and NK2 receptors mediate non-adrenergic noncholinergic excitatory neuromuscular transmission in the human ileum

Autor: V. Zagorodnyuk, Damiano Turini, P. Santicioli, C.A. Maggi

Publikováno v: Neuropeptides. 31:265-271

Tachykinin NK1 and NK2 receptor selective antagonists and agonists were used to study excitatory non-adrenergic non-cholinergic (NANC) transmission in circular muscle strips from human ileum by the sucrose-gap method. In the presence of atropine (1 m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627e27118276be6bdf05335436490900
https://doi.org/10.1016/s0143-4179(97)90058-5

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