Screening-based approach to discover effective platinum-based chemotherapies for cancers with poor prognosis.

Autor: Hristo P Varbanov, Fabien Kuttler, Damiano Banfi, Gerardo Turcatti, Paul J Dyson

Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0211268 (2019)

Drug combinations are extensively used to treat cancer and are often selected according to complementary mechanisms. Here, we describe a cell-based high-throughput screening assay for identification of synergistic combinations between broadly applied

Externí odkaz: https://doaj.org/article/7c3b2ddb85254fc1a19a6094a4e01329

www.nmrdb.org: Resurrecting and Processing NMR Spectra On-line

Autor: Damiano Banfi, Luc Patiny

Publikováno v: CHIMIA, Vol 62, Iss 4 (2008)

NMR spectroscopy is certainly the analytical methodology that provides the most information about a molecule but the long-term vision of this information is often lacking. We present here two innovative tools accessible free from the web. NMR assigne

Externí odkaz: https://doaj.org/article/62ad6358e5d5437a88210c0752f6fb34

Highly Potent Host-Specific Small-Molecule Inhibitor of Paramyxovirus and Pneumovirus Replication with High Resistance Barrier

Autor: Gerardo Turcatti, Melanie Brügger, Neeta Shrestha, Marc Chambon, Melanie M. Hierweger, Jonathan Vesin, Branka Horvat, Cyrille Mathieu, Dimitrios Fotiadis, Flavio M. Gall, Philippe Plattet, Marco P. Alves, Rainer Riedl, Damiano Banfi, David Kalbermatter

Publikováno v: mBio
mBio, 2021, 12 (6), pp.390-402. ⟨10.1128/mBio.02621-21⟩
mBio, Vol 12, Iss 6 (2021)
Shrestha, Neeta; Gall, Flavio Max; Mathieu, Cyrille; Hierweger, Melanie Michaela; Brügger, Melanie; Alves, Marco P.; Vesin, Jonathan; Banfi, Damiano; Kalbermatter, David; Horvat, Branka; Chambon, Marc; Turcatti, Gerardo; Fotiadis, Dimitrios; Riedl, Rainer; Plattet, Philippe (2021). Highly Potent Host-Specific Small-Molecule Inhibitor of Paramyxovirus and Pneumovirus Replication with High Resistance Barrier. mBio, 12(6), e0262121. American Society for Microbiology 10.1128/mBio.02621-21

Multiple enveloped RNA viruses of the family Paramyxoviridae and Pneumoviridae, like measles virus (MeV), Nipah virus (NiV), canine distemper virus (CDV), or respiratory syncytial virus (RSV), are of high clinical relevance. Each year a huge number o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0155abfd8d245019aa9b3ffb08d825e
https://cnrs.hal.science/hal-03777054/document

Image-Based Marker-Free Screening of GABA

Autor: Benjamin, Rappaz, Pascal, Jourdain, Damiano, Banfi, Fabien, Kuttler, Pierre, Marquet, Gerardo, Turcatti

Publikováno v: Slas Discovery

The ionotropic GABAA receptors represent the main target for different groups of widely used drugs having hypnotic and anxiolytic effects. So far, most approaches used to assess GABA activity involve invasive low -throughput electrophysiological tech

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2c3108e08ae1d4a795765a064dd54694
https://pubmed.ncbi.nlm.nih.gov/31779505

Versatile Synthesis of Boc Protected Hydrazinoacetic Acid and its Application to the Chemoselective Ligation of Tasp Molecules

Autor: Damiano Banfi, Manfred Mutter, Luc Patiny

Publikováno v: Protein & Peptide Letters. 11:539-542

This paper describes a convenient synthesis of protected hydrazine derivatives, i.e. 1,2-bis-Boc-hydrazinoacetic acid, and its application for hydrazone ligation techniques in convergent template assembled synthetic protein (TASP) synthesis.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90e3e02e0ccc3a4e5dabcd2b9ef86b8
https://doi.org/10.2174/0929866043406274