Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Damiana Lecoeuche"'
1
Akademický článek
Germinal center output is sustained by HELLS-dependent DNA-methylation-maintenance in B cells
Autor: Clara Cousu, Eléonore Mulot, Annie De Smet, Sara Formichetti, Damiana Lecoeuche, Jianke Ren, Kathrin Muegge, Matthieu Boulard, Jean-Claude Weill, Claude-Agnès Reynaud, Sébastien Storck
Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract HELLS/LSH (Helicase, Lymphoid Specific) is a SNF2-like chromatin remodelling protein involved in DNA methylation. Its loss-of-function in humans causes humoral immunodeficiency, called ICF4 syndrome (Immunodeficiency, Centromeric Instability
Externí odkaz: https://doaj.org/article/6f039c8a6d20420db31703b546655057
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2
Akademický článek
The whole-cell pertussis vaccine imposes a broad effector B cell response in mouse heterologous prime-boost settings
Autor: Viviana Valeri, Akhésa Sochon, Clara Cousu, Pascal Chappert, Damiana Lecoeuche, Pascal Blanc, Jean-Claude Weill, Claude-Agnès Reynaud
Publikováno v: JCI Insight, Vol 7, Iss 21 (2022)
ÍSince the introduction of new generation pertussis vaccines, resurgence of pertussis has been observed in many developed countries. Former whole-cell pertussis (wP) vaccines are able to protect against disease and transmission but have been replace
Externí odkaz: https://doaj.org/article/f572597211b04b79bd410d6d366a552a
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3
Akademický článek
B cell intrinsic and extrinsic factors impacting memory recall responses to SRBC challenge
Autor: Viviana Valeri, Akhésa Sochon, Chaoliang Ye, Xinru Mao, Damiana Lecoeuche, Simon Fillatreau, Jean-Claude Weill, Claude-Agnès Reynaud, Yi Hao
Publikováno v: Frontiers in Immunology, Vol 13 (2022)
MBCs (MBCs) generated in T-dependent immune responses can persist for a lifetime and rapidly react upon secondary antigen exposure to differentiate into plasma cells (PCs) and/or to improve the affinity of their BCR through new rounds of hypermutatio
Externí odkaz: https://doaj.org/article/544d1cda87624ca69cda57852d018a9c
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4
The whole-cell pertussis vaccine imposes a broad effector B cell response in mouse heterologous prime-boost settings
Autor: Viviana Valeri, Akhésa Sochon, Clara Cousu, Pascal Chappert, Damiana Lecoeuche, Pascal Blanc, Jean-Claude Weill, Claude-Agnès Reynaud
Publikováno v: JCI insight. 7(21)
ÍSince the introduction of new generation pertussis vaccines, resurgence of pertussis has been observed in many developed countries. Former whole-cell pertussis (wP) vaccines are able to protect against disease and transmission but have been replace
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e63b425a3157245f4fbf2187b6697ecd
https://pubmed.ncbi.nlm.nih.gov/36136586
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5
Klhl6 Deficiency Impairs Transitional B Cell Survival and Differentiation
Autor: Auriel Dahan, Frédérique Lembo, Annie De Smet, Christine Bole-Feysot, Jean-Claude Weill, Damiana Lecoeuche, Nicolas Cagnard, Delphine Sterlin, Barbara Bertocci, Tatiana Fadeev, Baptiste Gaillard, Claude-Agnès Reynaud, Julius Kühn
Publikováno v: The Journal of Immunology. 199:2408-2420
Klhl6 belongs to the KLHL gene family, which is composed of an N-terminal BTB-POZ domain and four to six Kelch motifs in tandem. Several of these proteins function as adaptors of the Cullin3 E3 ubiquitin ligase complex. In this article, we report tha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a2112edda63f661db98a08c110ab060
https://doi.org/10.4049/jimmunol.1700708
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6
Somatic diversification in the absence of antigen-driven responses is the hallmark of the IgM+IgD+CD27+ B cell repertoire in infants
Autor: Maria Mamani-Matsuda, Frédéric Gauthier, Claude-Agnès Reynaud, Corinne Cordier, Capucine Picard, Damiana Lecoeuche, Jean-Claude Weill, Sandra K. Weller
Publikováno v: The Journal of Experimental Medicine
Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2008, 205 (6), pp.1331-42. ⟨10.1084/jem.20071555⟩
The Journal of Experimental Medecine
The Journal of Experimental Medecine, The Rockefeller University Press, 2008, 205 (6), pp.1331-42. 〈10.1084/jem.20071555〉
Journal of Experimental Medicine, 2008, 205 (6), pp.1331-42. ⟨10.1084/jem.20071555⟩
International audience; T cell-dependent immune responses develop soon after birth, whereas it takes 2 yr for humans to develop T cell-independent responses. We used this dissociation to analyze the repertoire diversification of IgM(+)IgD(+)CD27(+) B
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0931002431ee87e4ab64c257748949
http://europepmc.org/articles/PMC2413031
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7
GILZ, a new target for the transcription factor FoxO3, protects T lymphocytes from interleukin-2 withdrawal-induced apoptosis
Autor: Muriel D. David, Marie Liesse Asselin-Labat, Jacques Bertoglio, Maria Christina Zennaro, Damiana Lecoeuche, Marc Pallardy, Armelle Biola-Vidamment
Publikováno v: Blood. 104(1)
Interleukin-2 (IL-2) withdrawal is a physiologic process inducing cell death in activated T lymphocytes. Glucocorticoid-induced leucine zipper (GILZ) has recently been identified as a protein modulating T-cell receptor activation by repressing variou
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2db43897912a33080ce1712e31f9507
https://pubmed.ncbi.nlm.nih.gov/15031210
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