Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Damian P, Hruszkewycz"'
Autor:
Nahiane Pipaón Fernández, Gregory Gaube, Kyla J. Woelk, Mathias Burns, Damian P. Hruszkewycz, David C. Leitch
Publikováno v:
ACS Catalysis. 12:6997-7003
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c38988a273985336d9830967fe9bce3
https://doi.org/10.1021/acscatal.2c01305
https://doi.org/10.1021/acscatal.2c01305
Publikováno v:
Reaction Chemistry & Engineering.
The Mizoroki–Heck arylation of electron-rich alkenes such as butyl vinyl ether often results in regioisomeric mixtures of products under typical reaction conditions. To discover new catalytic systems for achieving α-selective arylation, an alterna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c5b7698e382a36146f2e01c92db4488
https://doi.org/10.1039/d1re00124h
https://doi.org/10.1039/d1re00124h
Autor:
Christopher J. Nunn, Damian P. Hruszkewycz, Derek I. Wozniak, Justin M. Kaplan, David C. Leitch, Iulia I. Strambeanu, Kelsey F. VanGelder, Anna L. Dunn, Graham E. Dobereiner
Publikováno v:
Organometallics. 38:85-96
The Pd-catalyzed carbonylation of cyclic β-chloro enones using simple phosphine ligands is described. Screening identified P(Me)(t-Bu)2 as the most general ligand for an array of chloro enone electrophiles. The reaction scope has been evaluated on a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::760dcf3a7421a5ee0a6c1ecdd535b51e
https://doi.org/10.1021/acs.organomet.8b00468
https://doi.org/10.1021/acs.organomet.8b00468
Publikováno v:
Journal of the American Chemical Society. 140:22-25
An electrochemical method has been developed for selective benzylic iodination of methylarenes. The reactions feature the first use of N-hydroxyphthalimide as an electrochemical mediator for C–H oxidation to nonoxygenated products. The method provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4879d86b944e92fa64ef6c4d76c84b62
https://doi.org/10.1021/jacs.7b09744
https://doi.org/10.1021/jacs.7b09744
Publikováno v:
Chemical Science
A new method for Co/NHPI-catalyzed aerobic C–H oxygenation shows excellent tolerance of electronically diverse heterocycles.
A simple cobalt(ii)/N-hydroxyphthalimide catalyst system has been identified for selective conversion of benzylic meth
A simple cobalt(ii)/N-hydroxyphthalimide catalyst system has been identified for selective conversion of benzylic meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad82ba77b2ae5d337c7482adfcf68d3e
https://doi.org/10.1039/c6sc03831j
https://doi.org/10.1039/c6sc03831j
Autor:
Joseph, Becica, Damian P, Hruszkewycz, Janelle E, Steves, Jennifer M, Elward, David C, Leitch, Graham E, Dobereiner
Publikováno v:
Organic letters. 21(22)
Through targeted high-throughput experimentation (HTE), we have identified the Pd/AdBippyPhos catalyst system as an effective and general method to construct densely functionalized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b508e5c305004eb6110b0d51cbea9418
https://pubmed.ncbi.nlm.nih.gov/31651171
https://pubmed.ncbi.nlm.nih.gov/31651171
Autor:
Graham E. Dobereiner, David C. Leitch, Janelle E. Steves, Damian P. Hruszkewycz, Joseph Becica, Jennifer M. Elward
Sulfonamides are poor nucleophiles in Pd C-N coupling catalysis, hindering synthesis of densely-functionalized N,N-diaryl sulfonamide motifs relevant to medicinal chemistry. Through targeted high-throughput experimentation (HTE), we have identified t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3234f6f5f98b98c9e73e3da475ed7456
https://doi.org/10.26434/chemrxiv.9108461.v2
https://doi.org/10.26434/chemrxiv.9108461.v2
Autor:
David C. Leitch, Joseph Becica, Jennifer M. Elward, Graham E. Dobereiner, Janelle E. Steves, Damian P. Hruszkewycz
Sulfonamides are poor nucleophiles in Pd C-N coupling catalysis, hindering synthesis of densely-functionalized N,N-diaryl sulfonamide motifs relevant to medicinal chemistry. Through targeted high-throughput experimentation (HTE), we have identified t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cde1870679838312a7366f798a76dc21
https://doi.org/10.26434/chemrxiv.9108461.v1
https://doi.org/10.26434/chemrxiv.9108461.v1
Autor:
Damian P. Hruszkewycz, Patrick R. Melvin, Wei Dai, Nilay Hazari, Hemali P. Shah, Ainara Nova, Matthew T. Tudge, David Balcells
Publikováno v:
ACS Catalysis. 5:3680-3688
We describe the development of (η3-1-tBu-indenyl)2(μ-Cl)2Pd2, a versatile precatalyst scaffold for Pd-catalyzed cross-coupling. Our new system is more active than commercially available (η3-cinnamyl)2(μ-Cl)2Pd2 and is compatible with a range of N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f04c58aa2673f9428f92204845a33807
https://doi.org/10.1021/acscatal.5b00878
https://doi.org/10.1021/acscatal.5b00878
Publikováno v:
Journal of the American Chemical Society. 136:7300-7316
Despite widespread use of complexes of the type Pd(L)(η(3)-allyl)Cl as precatalysts for cross-coupling, the chemistry of related Pd(I) dimers of the form (μ-allyl)(μ-Cl)Pd2(L)2 has been underexplored. Here, the relationship between the monomeric a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b6a24c3a7127f1aebc7664db07909c
https://doi.org/10.1021/ja412565c
https://doi.org/10.1021/ja412565c