Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Damian J Krysan"'
Publikováno v:
eLife, Vol 12 (2023)
Candida albicans is one of the most common human fungal pathogens. C. albicans pathogenesis is tightly linked to its ability to under a morphogenetic transition from typically budding yeast to filamentous forms of hyphae and pseudohyphae. Filamentous
Externí odkaz:
https://doaj.org/article/84b08b487de340d7966b84213c4eefe7
Autor:
Benjamin J Chadwick, Tuyetnhu Pham, Xiaofeng Xie, Laura C Ristow, Damian J Krysan, Xiaorong Lin
Publikováno v:
eLife, Vol 11 (2022)
The environmental pathogen Cryptococcus neoformans claims over 180,000 lives each year. Survival of this basidiomycete at host CO2 concentrations has only recently been considered an important virulence trait. Through screening gene knockout librarie
Externí odkaz:
https://doaj.org/article/b434a87da9254dd5b9d35f7897075a76
Autor:
Virginia E Glazier, Damian J Krysan
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008399 (2020)
Externí odkaz:
https://doaj.org/article/7cd03ba35fc5498d92b901c5bc5fe9aa
Publikováno v:
PLoS Pathogens, Vol 14, Iss 12, p e1007342 (2018)
Externí odkaz:
https://doaj.org/article/b7b6c5fdcb274c8d8d7c692e09ee39d8
Autor:
Virginia E Glazier, Thomas Murante, Daniel Murante, Kristy Koselny, Yuan Liu, Dongyeop Kim, Hyun Koo, Damian J Krysan
Publikováno v:
PLoS Genetics, Vol 13, Iss 8, p e1006948 (2017)
Biofilm formation by Candida albicans is a key aspect of its pathobiology and is regulated by an integrated network of transcription factors (Bcr1, Brg1, Efg1, Ndt80, Rob1, and Tec1). To understand the details of how the transcription factors functio
Externí odkaz:
https://doaj.org/article/66d193f02cf34db08cd18c28a347d39a
Publikováno v:
PLoS Pathogens, Vol 13, Iss 6, p e1006407 (2017)
Candida albicans is frequently detected with heavy infection by Streptococcus mutans in plaque-biofilms from children with early-childhood caries (ECC). This cross-kingdom biofilm contains an extensive matrix of extracellular α-glucans that is produ
Externí odkaz:
https://doaj.org/article/766e024146e644c39692ec43a26e2fa3
Autor:
Zhifeng Liao, Nicolas Laurent, Nathalie Hirt-Burri, Corinne Scaletta, Philippe Abdel-Sayed, Wassim Raffoul, Shengkang Luo, Damian J. Krysan, Alexis Laurent, Lee Ann Applegate
Publikováno v:
European Burn Journal, Vol 5, Iss 3, Pp 249-270 (2024)
Thorough biological safety testing of topical therapeutic compounds and antimicrobials is a critical prerequisite for appropriate cutaneous wound care. Increasing pathogen resistance rates to traditional antibiotics and antifungals are driving the de
Externí odkaz:
https://doaj.org/article/499fd2cc4dbc400785de9e0beb7f1332
Autor:
Arielle Butts, Jennifer A Martin, Louis DiDone, Erin K Bradley, Mitchell Mutz, Damian J Krysan
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125927 (2015)
Cryptococcosis is one of the most important invasive fungal infections and is a significant contributor to the mortality associated with HIV/AIDS. As part of our program to repurpose molecules related to the selective estrogen receptor modulator (SER
Externí odkaz:
https://doaj.org/article/d788779a16c84687bcf4f7424a3d50c4
Autor:
Lauren Forbes, Katherine Ebsworth-Mojica, Louis DiDone, Shao-Gang Li, Joel S Freundlich, Nancy Connell, Paul M Dunman, Damian J Krysan
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129234 (2015)
Mycobacterium tuberculosis (Mtb) is well-established to be one of the most important bacterial pathogens for which new antimicrobial therapies are needed. Herein, we describe the development of a high throughput screening assay for the identification
Externí odkaz:
https://doaj.org/article/060bff0cd9594b89817399735d136871
Publikováno v:
PLoS Pathogens, Vol 10, Iss 6, p e1004139 (2014)
Externí odkaz:
https://doaj.org/article/c51ca875424d474eacf7a2fe56288d23