Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Damian J, Ralser"'
Autor:
Richard Weiten, Max Niemann, Eduard Below, Lea L. Friker, Damian J. Ralser, Marieta Toma, Glen Kristiansen, Oliver Hahn, Sabrina Zechel, Viktor Grünwald, Tobias Bald, Johannes Siewert, Torsten Pietsch, Manuel Ritter, Michael Hölzel, Markus Eckstein, Abdullah Alajati, Philipp Krausewitz, Niklas Klümper
Publikováno v:
Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)
Abstract Purpose Improved survival rates have been observed in castration‐resistant prostate cancer (CRPC) due to advancements in treatment options. However, individuals with brain metastases still have limited therapeutic options and an unfavorabl
Externí odkaz:
https://doaj.org/article/296319f737d046debd441f74e94d7c29
Autor:
Damian J. Ralser, Emmanuelle Herr, Luka de Vos, Zsófi Kulcsár, Romina Zarbl, Niklas Klümper, Gerrit H. Gielen, Alexander Philippe Maas, Friederike Hoffmann, Jörn Dietrich, Pia Kuster, Alexander Mustea, Nicole Glodde, Glen Kristiansen, Sebastian Strieth, Jennifer Landsberg, Dimo Dietrich
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract Background Inducible T cell costimulator ICOS is an emerging target in immuno-oncology. The aim of this study was to investigate the epigenetic regulation of ICOS in melanoma by DNA methylation. Methods We comprehensively investigate ICOS DN
Externí odkaz:
https://doaj.org/article/e3bb36e51ff44e6f9b8d700fc99a8755
Autor:
Niklas Klümper, Lennert Wüst, Jonas Saal, Damian J. Ralser, Romina Zarbl, Jonas Jarczyk, Johannes Breyer, Danijel Sikic, Bernd Wullich, Christian Bolenz, Florian Roghmann, Michael Hölzel, Manuel Ritter, Sebastian Strieth, Arndt Hartmann, Philipp Erben, Ralph M. Wirtz, Jennifer Landsberg, Dimo Dietrich, Markus Eckstein
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTPD-L1 status assessed by immunohistochemistry (IHC) has failed to reliably predict outcomes for patients with metastatic urothelial carcinoma (mUC) on immune checkpoint blockade (ICB). PD-L1 promoter methylation is an epigenetic mechanism tha
Externí odkaz:
https://doaj.org/article/db84a83835784401bcaeca4a8df3487d
Autor:
Mateja Condic, Thore Thiesler, Christian Staerk, Niklas Klümper, Jörg Ellinger, Eva K. Egger, Kirsten Kübler, Glen Kristiansen, Alexander Mustea, Damian J. Ralser
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Vulvar squamous cell carcinoma (VSCC) is an uncommon gynecologic malignancy but with an increasing incidence in recent years. Etiologically, VSCC is classified into two subtypes: HPV-dependent and HPV-independent. Localized VSCC i
Externí odkaz:
https://doaj.org/article/57fe9adfda1943c699a45879061aa79b
Autor:
Eva K. Egger, Freya Merker, Damian J. Ralser, Milka Marinova, Tim O. Vilz, Hanno Matthaei, Tobias Hilbert, Alexander Mustea
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
AimThis study aims to evaluate the incidence of postoperative ileus (POI) following cytoreductive surgery in epithelial ovarian cancer (EOC) patients and its impact on anastomotic leakage occurrence and postoperative complications.MethodsA total of 3
Externí odkaz:
https://doaj.org/article/0e7ea1ba0cdc42b6b5bb3d5fed0c4069
Autor:
Dimo Dietrich, Lutz Trojan, Niklas Klümper, Damian J Ralser, Romina Zarbl, Glen Kristiansen, Marieta Toma, Manuel Ritter, Michael Hölzel, Jörg Ellinger, Markus Eckstein, Danijel Sikic, Katrin Schlack, Andres Jan Schrader, Marc Rehlinghaus, Michèle J Hoffmann, Günter Niegisch, Annemarie Uhlig, Julie Steinestel, Konrad Steinestel, Ralph M Wirtz, Sebastian Strieth
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 8 (2021)
Externí odkaz:
https://doaj.org/article/6e349fc1c30b4c718dcf71148fb36faf
Autor:
Eva Katharina Egger, Damian J. Ralser, Kira Lindner, Florian Recker, Milka Marinova, Oleksandre Savchenko, Jan-Frederic Lau, Alexander Mustea
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundVaginal adenocarcinomas (VAC) are most often reported after intrauterine exposition to diethylstilbestrol (DES). Rarely, VACs are reported as a malignant transformation of vaginal adenosis or endometriosis, in the context of chromosomal abn
Externí odkaz:
https://doaj.org/article/0134c4b988ee486c932d574d81491806
Autor:
DAMIAN J. RALSER, MATEJA CONDIC, EVA EGGER, DOMINIQUE KOENSGEN, ALEXANDER MUSTEA, MATTHIAS B. STOPE
Publikováno v:
Anticancer Research. 42:5839-5845
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d92d3f84b67051225d077abacaebe7a5
https://doi.org/10.21873/anticanres.16092
https://doi.org/10.21873/anticanres.16092
Autor:
Dimo Dietrich, Niklas Klümper, Damian J Ralser, Emma Grace Bawden, Jenny Landsberg, Romina Zarbl, Glen Kristiansen, Marieta Toma, Manuel Ritter, Michael Hölzel, Jörg Ellinger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Lymphocyte activating 3 (LAG3, LAG-3, CD223) is a promising target for immune checkpoint inhibition in clear cell renal cell carcinoma (KIRC). The aim of this study was to investigate the epigenetic regulation of LAG3 in KIRC by methylatio
Externí odkaz:
https://doaj.org/article/bfb81be264254efd9d73310356bd1072
Autor:
Damian J. Ralser, Brigitte Strizek, Patrick Kupczyk, Birgit Stoffel-Wagner, Julia Altengarten, Andreas Müller, Joachim Woelfle, Ulrich Gembruch, Dietrich Klingmueller, Waltraut M. Merz, Anke Paschkowiak-Christes
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Background: Carney complex (CNC) is a rare multiple endocrine neoplasia syndrome with autosomal dominant inheritance. Affected individuals present with mucocutaneous lentigines/blue nevi, cardiac and noncardiac myxomatous tumors, and multiple endocri
Externí odkaz:
https://doaj.org/article/a475413c684b453492ef7cf378fcd069