Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Damian G. Weaver"'
Autor:
Lisa K. Ryan, Amy G Hise, Chowdhury Mobaswar Hossain, William Ruddick, Rezwana Parveen, Katie B. Freeman, Damian G. Weaver, Hema P. Narra, Richard W. Scott, Gill Diamond
Publikováno v:
Journal of Fungi, Vol 6, Iss 4, p 197 (2020)
Disseminated infection by Candida species represents a common, often life-threatening condition. Increased resistance to current antifungal drugs has led to an urgent need to develop new antifungal drugs to treat this pathogen. However, in vivo scree
Externí odkaz:
https://doaj.org/article/e4be0c5ead9742fcbaeb355d867fecf9
Autor:
Mobaswar Hossain Chowdhury, Lisa Kathleen Ryan, Kartikeya Cherabuddi, Katie B. Freeman, Damian G. Weaver, Jeffry C. Pelletier, Richard W. Scott, Gill Diamond
Publikováno v:
Journal of Fungi, Vol 4, Iss 1, p 30 (2018)
Invasive candidiasis caused by Candida albicans and non-albicans Candida (NAC) present a serious disease threat. Although the echinocandins are recommended as the first line of antifungal drug class, resistance to these agents is beginning to emerge,
Externí odkaz:
https://doaj.org/article/7c291340d255464084394970aeb7bff2
Autor:
Katie B. Freeman, Jeffrey C. Pelletier, Richard W. Scott, Damian G. Weaver, Simon D P Baugh, Allen B. Reitz, Sandeep Thanna, Anna L Chaly
Publikováno v:
Bioorganicmedicinal chemistry letters. 33
Invasive fungal infections have become an important healthcare issue due in large part to high mortality rates under standard of care (SOC) therapies creating an urgent need for new and effective anti-fungal agents. We have developed a series of non-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21c2c236b4255b27f99529de029b8d6
https://pubmed.ncbi.nlm.nih.gov/33316410
https://pubmed.ncbi.nlm.nih.gov/33316410
Autor:
Katie B. Freeman, Rezwana Parveen, Hema P. Narra, Lisa K. Ryan, Gill Diamond, William N. Ruddick, Richard W. Scott, Damian G. Weaver, Amy G. Hise, Chowdhury Mobaswar Hossain
Publikováno v:
Journal of Fungi
Volume 6
Issue 4
Journal of Fungi, Vol 6, Iss 197, p 197 (2020)
Volume 6
Issue 4
Journal of Fungi, Vol 6, Iss 197, p 197 (2020)
Disseminated infection by Candida species represents a common, often life-threatening condition. Increased resistance to current antifungal drugs has led to an urgent need to develop new antifungal drugs to treat this pathogen. However, in vivo scree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31672bffdce7af5631369fe043a474b
Autor:
Ashley Deviney, Katie B. Freeman, David B Whitman, Gill Diamond, Allen B. Reitz, Anna L Chaly, Mark Pulse, Richard W. Scott, Simon D P Baugh, Damian G. Weaver, William J. Weiss, Phung Nguyen, Sandeep Thanna
Publikováno v:
Open Forum Infectious Diseases
Background We are developing a series of small nonpeptide mimics of host defense proteins (smHDPs) for antifungal applications. MICs < 0.1 µg/ ml have been demonstrated against multiple yeast and mold species. Their potential therapeutic utility has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd47eda23814dfa1f4e9098012f6285
http://europepmc.org/articles/PMC7776474
http://europepmc.org/articles/PMC7776474
Autor:
Richard W. Scott, Kartikeya Cherabuddi, Gill Diamond, Damian G. Weaver, Jeffry C Pelletier, Lisa K. Ryan, Mobaswar Hossain Chowdhury, Katie B. Freeman
Publikováno v:
Journal of Fungi; Volume 4; Issue 1; Pages: 30
Journal of Fungi, Vol 4, Iss 1, p 30 (2018)
Journal of Fungi
Journal of Fungi, Vol 4, Iss 1, p 30 (2018)
Journal of Fungi
Invasive candidiasis caused by Candida albicans and non-albicans Candida (NAC) present a serious disease threat. Although the echinocandins are recommended as the first line of antifungal drug class, resistance to these agents is beginning to emerge,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89300b6019c7bf7445d1edd53c6082c0
Autor:
Kristina M. DiFranco, Richard W. Scott, Klaudia Falkovsky, Kartikeya Cherabuddi, Lorenzo P. Menzel, Michael J. Costanzo, Rafael Vorona, Damian G. Weaver, Gill Diamond, Jorge A. Masso-Silva, Lisa K. Ryan, Katie B. Freeman, David C. Brice, Hossain Mobaswar Chowdhury, Andrew Malsbary, William N. Ruddick
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Lethal systemic fungal infections of Candida species are increasingly common, especially in immune compromised patients. By in vitro screening of small molecule mimics of naturally occurring host defense peptides (HDP), we have identified several act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94ef24c021bf94509e0685cea2828d1
https://pubmed.ncbi.nlm.nih.gov/28659617
https://pubmed.ncbi.nlm.nih.gov/28659617
Autor:
Damian G. Weaver, William M. Barker, Christopher T. Saeui, Karin Worm, Robert N. DeHaven, Joel A. Cassel, Doreen-Marie S. Dulay, Rosalyn C. Green, Bernice L. Brogdon, Christopher J. LaBuda, Gabriel J. Stabley, Steven A. Smith, Michael Koblish, Roland E. Dolle
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:5004-5008
Recently sulfamoyl benzamides were identified as a novel series of cannabinoid receptor ligands. Replacing the sulfonamide functionality and reversing the original carboxamide bond led to the discovery of N-(3-(morpholinomethyl)-phenyl)-amides as pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a2d7cab39a1d9528a999f22400e8c9d
https://doi.org/10.1016/j.bmcl.2009.07.057
https://doi.org/10.1016/j.bmcl.2009.07.057
Autor:
Harvey Rubin, Richard W. Scott, Damian G. Weaver, H. Marie Loughran, Allen B. Reitz, Katie B. Freeman, Michael J. Costanzo, Trevor Selwood, Jay E. Wrobel, Takahiro Yano
Publikováno v:
Bioorganicmedicinal chemistry letters. 25(2)
The Gram-negative bacterium Acinetobacter baumannii is an opportunistic pathogen in humans and infections are poorly treated by current therapy. Recent emergence of multi-drug resistant strains and the lack of new antibiotics demand an immediate acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60e84c4f328185e277375d62bc7e04d7
https://pubmed.ncbi.nlm.nih.gov/25496770
https://pubmed.ncbi.nlm.nih.gov/25496770
Autor:
Bernice L. Brogdon, Michael Koblish, Christopher T. Saeui, Bertrand Le Bourdonnec, Roland E. Dolle, Damian G. Weaver, Allan J. Goodman, Karin Worm, Joel A. Cassel, Robert N. DeHaven, Robert L. Broadrup, Steve Smith, Christopher J. LaBuda, Guo-Hua Chu
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(20)
Replacement of the phenyl ring in our previous (morpholinomethyl)aniline carboxamide cannabinoid receptor ligands with a pyridine ring led to the discovery of a novel chemical series of CB2 ligands. Compound 3, that is, 2,2-dimethyl-N-(5-methyl-4-(mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92190c9dee633d84b4e95697f96c3099
https://pubmed.ncbi.nlm.nih.gov/19736007
https://pubmed.ncbi.nlm.nih.gov/19736007