Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Damian E. Berardi"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract UNC51-like kinase-1 (ULK1) is the catalytic component of the autophagy pre-initiation complex that stimulates autophagy via phosphorylation of ATG14, BECLN1 and other autophagy proteins. ULK1 has also been shown to specifically promote mitop
Externí odkaz:
https://doaj.org/article/b8691ae8b4a84a7988222931dcdad9d8
Autor:
Damian E. Berardi, Paola B. Campodónico, Maria Ines Díaz Bessone, Alejandro J. Urtreger, Laura B. Todaro
Publikováno v:
International Journal of Breast Cancer, Vol 2011 (2011)
Autophagy is a catabolic process responsible for the degradation and recycling of long-lived proteins and organelles by lysosomes. This degradative pathway sustains cell survival during nutrient deprivation, but in some circumstances, autophagy leads
Externí odkaz:
https://doaj.org/article/7a04aebf49384c008e75046be0e0ed48
Autor:
Damian E. Berardi, Althea Bock-Hughes, Alexander R. Terry, Lauren E. Drake, Grazyna Bozek, Kay F. Macleod
Publikováno v:
Science advances. 8(41)
Hepatic steatosis is a major etiological factor in hepatocellular carcinoma (HCC), but factors causing lipid accumulation leading to HCC are not understood. We identify BNIP3 (a mitochondrial cargo receptor) as an HCC suppressor that mitigates agains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c904f9f6b459785f4e8995f0b89114
https://pubmed.ncbi.nlm.nih.gov/36223464
https://pubmed.ncbi.nlm.nih.gov/36223464
Autor:
Beatriz C. Moraes, Helder V. Ribeiro-Filho, Allan P. Roldão, Elaine F. Toniolo, Gustavo P. B. Carretero, Germán G. Sgro, Fernanda A. H. Batista, Damian E. Berardi, Victoria R. S. Oliveira, Rebeka Tomasin, Felipe M. Vieceli, Dimitrius T. Pramio, Alexandre B. Cardoso, Ana C. M. Figueira, Shaker C. Farah, Lakshmi A. Devi, Camila S. Dale, Paulo S. L. de Oliveira, Deborah Schechtman
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Chronic pain is a major health issue, and the search for new analgesics has become increasingly important because of the addictive properties and unwanted side effects of opioids. To explore potentially new drug targets, we investigated mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57534e0f4819a1b63072a80b50abe7b
Autor:
Damian E. Berardi, Kay F. Macleod
Publikováno v:
Cancer Research. 82:951-951
Mitophagy is induced in response to physiological stresses, including hypoxia, as an adaptive response that decreases mitochondrial mass to promote efficient use of limiting nutrients. BNIP3L/NIX is a mitophagy cargo receptor that integrates into the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd6412366aa843e6529940bb7de627e4
https://doi.org/10.1158/1538-7445.am2022-951
https://doi.org/10.1158/1538-7445.am2022-951
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
UNC51-like kinase-1 (ULK1) is the catalytic component of the autophagy pre-initiation complex that stimulates autophagy via phosphorylation of ATG14, BECLN1 and other autophagy proteins. ULK1 has also been shown to specifically promote mitophagy but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6b1ce5a599e162fda2803c13459db1
https://pubmed.ncbi.nlm.nih.gov/34654847
https://pubmed.ncbi.nlm.nih.gov/34654847
Autor:
Laura B. Todaro, Stefano M. Cirigliano, María Giselle Peters, Damian E. Berardi, Damian Ignacio Delbart, Alejandro J. Urtreger, María I. Díaz Bessone
Purpose: Retinoids have proved to be effective for hematologic malignancies treatment but till nowadays, their use as single agent for the solid tumor’s management is still controversial. All-trans retinoic acid (ATRA), the main active metabolite o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3300b46fbad155e1b2e1f0b588fe2c5
https://link.springer.com/article/10.1007/s00432-020-03368-7
https://link.springer.com/article/10.1007/s00432-020-03368-7
Autor:
Luciana Cañonero, Andrea Motter, María Agustina Taruselli, Maria de Las Nieves Pelagatti, Lizeth Ariza Bareño, Natalia Loreley Amigo, Miriam J. Diament, Stefano M. Cirigliano, María Giselle Peters, Alexis Edelstein, Laura B. Todaro, Damian E. Berardi, Alejandro J. Urtreger, María I. Díaz Bessone
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Breast cancer is the leading cause of cancer death among women worldwide. Blocking a single signaling pathway is often an ineffective therapy, especially in the case of aggressive or drug-resistant tumors. Since we have previously described the mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1139227d176b6a921f7dde4c506f5b85
https://pubmed.ncbi.nlm.nih.gov/33723318
https://pubmed.ncbi.nlm.nih.gov/33723318
Autor:
Damian E. Berardi, Laura B. Todaro, Cristina E. Rodríguez, Marianela Abrigo, Elisa Bal de Kier Joffé, Gabriel L. Fiszman
Publikováno v:
Journal of Cellular Biochemistry. 119:1381-1391
Breast cancer human cells culture as spheroids develop autophagy and apoptosis, which promotes Trastuzumab resistance in HER2 overexpressing cells. Our aim was to study the association of the hostile environment developed in 3D with the breast cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a65a89d4756114c8a1e73e7bcab1b5
https://doi.org/10.1002/jcb.26298
https://doi.org/10.1002/jcb.26298
Autor:
Alejandro J. Urtreger, Damian E. Berardi, Laura B. Todaro, Elisa Bal de Kier Joffé, Gabriel L. Fiszman, Stefano M. Cirigliano, María I. Díaz Bessone, Cristina E. Rodríguez, Carolina Flumian
Publikováno v:
Journal of Cellular Biochemistry. 117:730-740
Protein kinase C (PKC) is a family of serine/threonine kinases that regulate diverse cellular functions including cell death, proliferation, and survival. Recent studies have reported that PKCδ, are involved in apoptosis or autophagy induction. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4e639ed7d069321748967b39b8d3a8a
https://doi.org/10.1002/jcb.25358
https://doi.org/10.1002/jcb.25358