Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Damian C. Bell"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Ion channels are key signaling proteins found throughout the body; they are critical in many, wide-ranging physiological processes, from gene expression, sensory perception and processing to the cardiac action potential. When ion channel activity goe
Externí odkaz:
https://doaj.org/article/d02b4945741346e0bf6751056a0542e2
Adventures and Advances in Time Travel With Induced Pluripotent Stem Cells and Automated Patch Clamp
Autor:
Kadla R. Rosholm, Beatrice Badone, Stefania Karatsiompani, David Nagy, Fitzwilliam Seibertz, Niels Voigt, Damian C. Bell
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
In the Hollywood blockbuster “The Curious Case of Benjamin Button” a fantastical fable unfolds of a man’s life that travels through time reversing the aging process; as the tale progresses, the frail old man becomes a vigorous, vivacious young
Externí odkaz:
https://doaj.org/article/1bff1af0524544e8a548cf01572cad33
Autor:
Damian C, Bell, Mark L, Dallas
Publikováno v:
Advances in experimental medicine and biology. 1349
Since its development on the cusp of the new millennium, automated patch clamp (APC) technology has matured over the last two decades. The increased throughput it afforded promised a new paradigm in ion channel recordings: It offered the potential to
Autor:
Bernard, Fermini, Damian C, Bell
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 117:107184
There is no refuting that America's population is growing older: for the first time in US history, by 2034 older adults (defined as65 years of age) are projected to outnumber children under the age of 18, representing approximately 70 million people
Autor:
Damian C. Bell, Mark L. Dallas
Publikováno v:
Ion Channels in Biophysics and Physiology ISBN: 9789811642531
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28bb2aec635e8da9a55090714c4fe0a8
https://doi.org/10.1007/978-981-16-4254-8_2
https://doi.org/10.1007/978-981-16-4254-8_2
Autor:
Damian C, Bell, Bernard, Fermini
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 111:107114
There is no doubt that automated patch clamp (APC) technology has revolutionized research in biomedical science. High throughput ion channel screening is now an integral part of the development and safety profiling of the majority of new chemical ent
Autor:
Damian C. Bell, Bernard Fermini
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 110:107072
There is no doubt that automated patch clamp (APC) technology has revolutionized research in biomedical science. High throughput ion channel screening is now an integral part of the development and safety profiling of the majority of new chemical ent
Autor:
Naja Møller M. Sørensen, Sachin Surade, Aneesh Karatt-Vellatt, Tim Luetkens, Alice M. Luther, Neil J. Butt, John McCafferty, Ed W. Masters, Damian C. Bell
Publikováno v:
Biophysical Journal. 116:172a-173a
Autor:
Gareth R. Tibbs, Matthew T. Valley, John H. Riley, Harma K. Turbendian, Steven A. Siegelbaum, Damian C. Bell, Lei Zhou
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 458:259-272
We explored the structural basis of voltage sensing in the HCN1 hyperpolarization-activated cyclic nucleotide-gated cation channel by examining the relative orientation of the voltage sensor and pore domains. The opening of channels engineered to con
Publikováno v:
The Journal of General Physiology
The positively charged S4 transmembrane segment of voltage-gated channels is thought to function as the voltage sensor by moving charge through the membrane electric field in response to depolarization. Here we studied S4 movements in the mammalian H