Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Damian Bartuzi"'
Autor:
Damian Bartuzi, Ewa Kędzierska, Katarzyna M. Targowska-Duda, Oliwia Koszła, Tomasz M. Wróbel, Simon Jademyr, Tadeusz Karcz, Katarzyna Szczepańska, Piotr Stępnicki, Olga Wronikowska-Denysiuk, Grażyna Biała, Jadwiga Handzlik, Jesper L. Kristensen, Antti Poso, Agnieszka A. Kaczor
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Anxiety is a troublesome symptom for many patients, especially those suffering from schizophrenia. Its regulation involves serotonin receptors, targeted e.g. by antipsychotics or psychedelics such as LSD. 5-HT2A receptors are known for an ex
Externí odkaz:
https://doaj.org/article/e8d54c16692c4f768e6532bff908e43f
Autor:
Piotr Stępnicki, Sylwia Wośko, Agata Bartyzel, Agata Zięba, Damian Bartuzi, Klaudia Szałaj, Tomasz M. Wróbel, Emilia Fornal, Jens Carlsson, Ewa Kędzierska, Ewa Poleszak, Marián Castro, Agnieszka A. Kaczor
Publikováno v:
Molecules, Vol 28, Iss 10, p 4211 (2023)
The dopamine D2 receptor, which belongs to the family of G protein-coupled receptors (GPCR), is an important and well-validated drug target in the field of medicinal chemistry due to its wide distribution, particularly in the central nervous system,
Externí odkaz:
https://doaj.org/article/9722a60b29344f989fa26a12ffad5099
Publikováno v:
Molecules, Vol 28, Iss 1, p 178 (2022)
Allosteric modulation of G protein-coupled receptors (GPCRs) is nowadays a hot topic in medicinal chemistry. Allosteric modulators, i.e., compounds which bind in a receptor site topologically distinct from orthosteric sites, exhibit a number of advan
Externí odkaz:
https://doaj.org/article/3723876c7fb04968ae4c87dcd67ceb5b
Publikováno v:
Molecules, Vol 27, Iss 4, p 1335 (2022)
The dopamine D2 receptor, belonging to the class A G protein-coupled receptors (GPCRs), is an important drug target for several diseases, including schizophrenia and Parkinson’s disease. The D2 receptor can be activated by the natural neurotransmit
Externí odkaz:
https://doaj.org/article/eac13153e8bb45fd8566b55447e2cff2
Publikováno v:
Molecules, Vol 22, Iss 7, p 1188 (2017)
In recent years, our understanding of function of G protein-coupled receptors (GPCRs) has changed from a picture of simple signal relays, transmitting only a particular signal to a particular G protein heterotrimer, to versatile machines, capable of
Externí odkaz:
https://doaj.org/article/ff94629b65f5499e9f7f6ad71c5ac6b7
Publikováno v:
Molecules, Vol 22, Iss 2, p 340 (2017)
The growing number of studies on G protein-coupled receptors (GPCRs) family are a source of noticeable improvement in our understanding of the functioning of these proteins. GPCRs are responsible for a vast part of signaling in vertebrates and, as su
Externí odkaz:
https://doaj.org/article/337fa4c155424ff3a38e6584bc046283
Autor:
Justyna Żuk, Damian Bartuzi, Andrea G. Silva, Monika Pitucha, Oliwia Koszła, Tomasz M. Wróbel, Dariusz Matosiuk, Marián Castro, Agnieszka A. Kaczor
Publikováno v:
Pharmacological Reports. 74:406-424
Background Allosteric modulation of G protein-coupled receptors (GPCRs) is nowadays one of the hot topics in drug discovery. In particular, allosteric modulators of D2 receptor have been proposed as potential modern therapeutics to treat schizophreni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acae1e3ee8c2d940acc168d9d722a02f
https://doi.org/10.1007/s43440-021-00352-x
https://doi.org/10.1007/s43440-021-00352-x
Publikováno v:
Molecules (Basel, Switzerland). 27(4)
The dopamine D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2d3cb3ccf8b91088afe60c8dbc30d85
https://pubmed.ncbi.nlm.nih.gov/35209123
https://pubmed.ncbi.nlm.nih.gov/35209123
Publikováno v:
Molecules. 28:178
Allosteric modulation of G protein-coupled receptors (GPCRs) is nowadays a hot topic in medicinal chemistry. Allosteric modulators, i.e., compounds which bind in a receptor site topologically distinct from orthosteric sites, exhibit a number of advan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0593082b9078eade3f6256bf9c8a7c27
https://doi.org/10.3390/molecules28010178
https://doi.org/10.3390/molecules28010178
Autor:
Justyna, Żuk, Damian, Bartuzi, Andrea G, Silva, Monika, Pitucha, Oliwia, Koszła, Tomasz M, Wróbel, Dariusz, Matosiuk, Marián, Castro, Agnieszka A, Kaczor
Publikováno v:
Pharmacological reports : PR. 74(2)
Allosteric modulation of G protein-coupled receptors (GPCRs) is nowadays one of the hot topics in drug discovery. In particular, allosteric modulators of DTo address some subtle structural and stereochemical aspects of allosteric modulation of DOur m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41de01a3b20eeb24c59d5f1fd366f749
https://pubmed.ncbi.nlm.nih.gov/35064921
https://pubmed.ncbi.nlm.nih.gov/35064921