Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Damian Ackermann"'
Autor:
Stefan Pitsch, Philipp Wenter, Alfred Stutz, Luc Reymond, Sébastien Porcher, Andreas Peer, Evelyne Muller, Muthulaniappan Meyyappan, Frédéric Meylan, Cyrille Denarie, Damian Ackermann, Xiaolin Wu
Publikováno v:
CHIMIA, Vol 59, Iss 11 (2005)
Our group is working on the development of reliable access to biologically relevant, long, and modified RNA sequences. Here, we briefly present the chemical synthesis of such sequences with 2?-O-triisopropylsilyloxymethyl (= 2?-O-tom) protected ribon
Externí odkaz:
https://doaj.org/article/40fa4024082f40dcaf6a93389e43a849
Publikováno v:
CHIMIA, Vol 55, Iss 10 (2001)
The determination of the solution structure of small non-natural oligopeptides and oligonucleotides by NMR, which is one of the main research topics of our group, is illustrated on the example of an 8-mer p-DNA duplex. p-DNA, the 3'-desoxy analogue o
Externí odkaz:
https://doaj.org/article/6bf76c9b6a624baa8982032e904ce348
Publikováno v:
Organic Process Research & Development. 27:65-77
Publikováno v:
Angewandte Chemie. 124:6875-6879
Publikováno v:
Comptes Rendus Chimie. 14:819-825
We have developed modular assays based on aptamer displacement or protein-dependent reporter ribozymes for the screening of small molecule inhibitors. Thereby, chemical space can be explored in a rapid, focused, and modular manner, by indirectly taki
Autor:
Alexander Heckel, Jeffrey S. Hannam, Chandra Shekhar Purohit, Damian Ackermann, Michael Famulok, Thorsten Schmidt
Publikováno v:
Nature Nanotechnology
Mechanically interlocked molecules such as rotaxanes and catenanes have potential as components of molecular machinery. Rotaxanes consist of a dumb-bell-shaped molecule encircled by a macrocycle that can move unhindered along the axle, trapped by bul
Autor:
Damian Ackermann, Michael Famulok, Peter Broekmann, Alexander Heckel, Thorsten Schmidt, Goran Rasched
Publikováno v:
Angewandte Chemie. 120:981-984
Autor:
Damian Ackermann, Robert Häner
Publikováno v:
Helvetica Chimica Acta. 87:2790-2804
Phenanthrene-1,2-dimethanol was incorporated into oligodeoxynucleotides via formation of phosphodiester bonds (cf. Scheme 1). If placed at internal positions in a DNA duplex, a strong reduction of duplex stability is observed (Table 1). Terminal atta
Publikováno v:
Chemical Communications
The synthesis of a trifluoromethylphenyl diazirine photoaffinity probe of the cytohesin inhibitor SecinH3 is described. The probe exhibits improved labelling efficiency over a benzophenone-based probe and thus is more suitable for photoaffinity label
Autor:
Cristina Amparo Hagmann, Janos Ludwig, Tsan Sam Xiao, Thomas Gramberg, Veit Hornung, Damian Ackermann, Sabine Wittmann, Marion Goldeck, Thomas Zillinger, Liudmila Andreeva, Martin Schlee, Anna-Maria Herzner, Christoph Coch, Kirsten Kübler, Karl-Peter Hopfner, Tengchuan Jin, Winfried Barchet, Eva Bartok, Steven Wolter, Christina Mertens, Gunther Hartmann
Publikováno v:
Nature immunology. 16(10)
Cytosolic DNA that emerges during infection with a retrovirus or DNA virus triggers antiviral type I interferon responses. So far, only double-stranded DNA (dsDNA) over 40 base pairs (bp) in length has been considered immunostimulatory. Here we found