Zobrazeno 1 - 10
of 271
pro vyhledávání: '"Damião Pergentino de Sousa"'
Autor:
Damião Pergentino de Sousa, Francisco de Assis Oliveira, Daniel Dias Rufino Arcanjo, Diogo Vilar da Fonsêca, Allana Brunna S. Duarte, Celma de Oliveira Barbosa, Thomas Prates Ong, Timothy John Brocksom
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1185 (2024)
The importance of essential oils and their components in the industrial sector is attributed to their chemical characteristics and their application in the development of products in the areas of cosmetology, food, and pharmaceuticals. However, the p
Externí odkaz:
https://doaj.org/article/c6c75127d50b445ba5cb7e41335bc088
Autor:
Rafael Limongi de Souza, Luíza Carolina França Opretzka, Mayara Castro de Morais, Camila de Oliveira Melo, Brunna Emanuelly Guedes de Oliveira, Damião Pergentino de Sousa, Cristiane Flora Villarreal, Elquio Eleamen Oliveira
Publikováno v:
Pharmaceuticals, Vol 17, Iss 1, p 17 (2023)
Carvacryl acetate (CA) is a monoterpene obtained from carvacrol, which exhibits anti-inflammatory activity. However, its low solubility in aqueous media limits its application and bioavailability. Herein, we aimed to develop a carvacryl acetate nanoe
Externí odkaz:
https://doaj.org/article/2685eb9c5f2a46f7bb7f9bfd5e470882
Autor:
Martin Wurtele, Camila Coelho, Gloria Gallo, Claudia Campos, Leon Hardy, Yunierkis Perez Castillo, Masamitsu Moriwaki, Mahendra P. Kapoor, Damião Pergentino de Sousa
Publikováno v:
Journal of Chemistry, Vol 2023 (2023)
The main protease (Mpro) of SARS-CoV-2 is a well-established drug target for rational drug design of COVID-19 inhibitors. To address the serious challenge of COVID-19, we have performed biochemical inhibition screens with recombinantly expressed SARS
Externí odkaz:
https://doaj.org/article/bbfa5795378245e09150430806efb6d7
Autor:
Lázaro Gomes do Nascimento, Mayara Castro de Morais, José Klidenberg de Oliveira Júnior, Edeltrudes de Oliveira Lima, Damião Pergentino de Sousa
Publikováno v:
Journal of Chemistry, Vol 2023 (2023)
Derivatives of cinnamic acid have several pharmacological actions, such as antimicrobial activity. Therefore, in the present study, a series of fourteen alkyl and aryl derivatives from (E)-2-nitrocinnamic acid were obtained using Fischer esterificati
Externí odkaz:
https://doaj.org/article/a997f66159c84c708239b1362ad735c7
Autor:
Mayara Castro de Morais, Gisele Alves Medeiros, Fernanda Silva Almeida, Juliana da Câmara Rocha, Yunierkis Perez-Castillo, Tatjana de Souza Lima Keesen, Damião Pergentino de Sousa
Publikováno v:
Molecules, Vol 28, Iss 6, p 2844 (2023)
Leishmania infantum is the etiological agent of visceral leishmaniasis (VL) in South America, the Mediterranean basin, and West and Central Asia. The most affected country, Brazil, reported 4297 VL cases in 2017. L. infantum is transmitted by female
Externí odkaz:
https://doaj.org/article/dce3613366804372aa47e382ee58c441
Autor:
Lúcio Ricardo Leite Diniz, Leonardo Luiz Calado, Allana Brunna Sucupira Duarte, Damião Pergentino de Sousa
Publikováno v:
Metabolites, Vol 13, Iss 2, p 276 (2023)
An intense effort has been focused on new therapeutic approaches and the development of technologies for more efficient and rapid wound healing. The research for plants used for long time in traditional medicine in the treatment of wound has become a
Externí odkaz:
https://doaj.org/article/ea942eeec7ea4d868e31b4b061fb6c95
Autor:
Mayara Castro de Morais, Edeltrudes de Oliveira Lima, Yunierkis Perez-Castillo, Damião Pergentino de Sousa
Publikováno v:
Molecules, Vol 28, Iss 4, p 1918 (2023)
The severity of infectious diseases associated with the resistance of microorganisms to drugs highlights the importance of investigating bioactive compounds with antimicrobial potential. Therefore, nineteen synthetic cinnamides and cinnamates having
Externí odkaz:
https://doaj.org/article/3385f6ab1a1a423a984ced00fa79edef
Autor:
Julyanne Maria Saraiva de Sousa, Thaís Amanda de Lima Nunes, Raiza Raianne Luz Rodrigues, João Paulo Araújo de Sousa, Maria da Conceição Albuquerque Val, Francisco Alex da Rocha Coelho, Airton Lucas Sousa dos Santos, Nicolle Barreira Maciel, Vanessa Maria Rodrigues de Souza, Yasmim Alves Aires Machado, Paulo Sérgio de Araújo Sousa, Alyne Rodrigues de Araújo, Jefferson Almeida Rocha, Damião Pergentino de Sousa, Marcos Vinicius da Silva, Daniel Dias Rufino Arcanjo, Klinger Antônio da Franca Rodrigues
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 183 (2023)
Leishmaniasis is a group of infectious-parasitic diseases with high mortality rates, and endemic in many regions of the globe. The currently available drugs present serious problems such as high toxicity, costs, and the emergence of drug resistance.
Externí odkaz:
https://doaj.org/article/a39761981905449492c38756f7ee1c33
Autor:
Danielly Silva de Melo, José Arimatéa de Oliveira Nery Neto, Maisa de Sousa dos Santos, Vinícius Duarte Pimentel, Rita de Cássia Viana Carvalho, Valéria Carlos de Sousa, Ruy Gabriel Costa Sousa, Lázaro Gomes do Nascimento, Michel Muálem de Moraes Alves, Daniel Dias Rufino Arcanjo, Damião Pergentino de Sousa, Fernando Aécio de Amorim Carvalho
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2701 (2022)
Isopropyl gallate (IPG) is a polyphenol obtained from alterations in the gallic acid molecule via acid catalysis with previously reported leishmanicidal and trypanocidal activities. The present study aims to evaluate in silico binding activity toward
Externí odkaz:
https://doaj.org/article/73e0da34676749d5923b2fbfc0e27fe2
Autor:
Lúcio Ricardo Leite Diniz, Hatem A. Elshabrawy, Marilia Trindade S. Souza, Allana Brunna Sucupira Duarte, Nikhil Madhav, Damião Pergentino de Sousa
Publikováno v:
Biomolecules, Vol 12, Iss 11, p 1544 (2022)
Acute kidney injury (AKI) has been increasingly reported in critically-ill COVID-19 patients. Moreover, there was significant positive correlation between COVID-19 deaths and renal disorders in hospitalized COVID-19 patients with underlying comorbidi
Externí odkaz:
https://doaj.org/article/353b3f4426eb45578fb160419b67a72f