Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Damián Lobato‐Márquez"'
Autor:
Damián Lobato-Márquez, José Javier Conesa, Ana Teresa López-Jiménez, Michael E. Divine, Jonathan N. Pruneda, Serge Mostowy
Publikováno v:
Autophagy Reports, Vol 2, Iss 1 (2023)
Septins are cytoskeletal proteins implicated in numerous cellular processes including cytokinesis and morphogenesis. In the case of infection by Shigella flexneri, septins assemble into cage-like structures that entrap cytosolic bacteria targeted by
Externí odkaz:
https://doaj.org/article/436bf4795b76401d890df3ba3027711b
Publikováno v:
European Journal of Cell Biology, Vol 102, Iss 4, Pp 151359- (2023)
Staphylococcus aureus, a Gram-positive bacterial pathogen, is an urgent health threat causing a wide range of clinical infections. Originally viewed as a strict extracellular pathogen, accumulating evidence has revealed S. aureus to be a facultative
Externí odkaz:
https://doaj.org/article/2a4e19b813af4c758b710d43022eaf83
Autor:
Sydney L. Miles, Vincenzo Torraca, Zoe A. Dyson, Ana Teresa López-Jiménez, Ebenezer Foster-Nyarko, Damián Lobato-Márquez, Claire Jenkins, Kathryn E. Holt, Serge Mostowy
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Enteroinvasive Escherichia coli (EIEC) and Shigella are closely related agents of bacillary dysentery. It is widely viewed that EIEC and Shigella species evolved from E. coli via independent acquisitions of a large virulence plasmid (pINV) e
Externí odkaz:
https://doaj.org/article/c4d043d4f7ee43a1a46f60e1377649ae
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/abf193106edc4c27a6b392ee28887133
Autor:
Damián Lobato-Márquez, Jingwei Xu, Gizem Özbaykal Güler, Adaobi Ojiakor, Martin Pilhofer, Serge Mostowy
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Septins are cytoskeletal proteins that assemble into complexes and contribute to immunity by entrapping intracellular bacteria in cage-like structures. Here, Lobato-Márquez et al. reconstitute septin cages in vitro using purified recombinant complex
Externí odkaz:
https://doaj.org/article/7bfe02646c054d8c8ec6e9ed6237ffa9
Autor:
Pamela P. Lee, Damián Lobato-Márquez, Nayani Pramanik, Andrea Sirianni, Vanessa Daza-Cajigal, Elizabeth Rivers, Alessia Cavazza, Gerben Bouma, Dale Moulding, Kjell Hultenby, Lisa S. Westerberg, Michael Hollinshead, Yu-Lung Lau, Siobhan O. Burns, Serge Mostowy, Mona Bajaj-Elliott, Adrian J. Thrasher
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Wiskott-Aldrich syndrome protein (WASp) is essential for controlling the cytoskeleton, but its function in innate immunity is unclear. Here the authors show that WASp deficiency is associated with dysregulated septin cage formation, excessive inflamm
Externí odkaz:
https://doaj.org/article/7f189439f64c4318ac3cf0baaa3c3614
Publikováno v:
Toxins, Vol 7, Iss 2, Pp 478-492 (2015)
kis-kid, the auxiliary maintenance system of plasmid R1 and copB, the auxiliary copy number control gene of this plasmid, contribute to increase plasmid replication efficiency in cells with lower than average copy number. It is thought that Kis antit
Externí odkaz:
https://doaj.org/article/3f3137faff334e44bcdf02d50d21317a
Publikováno v:
Bio-Protocol, Vol 7, Iss 9 (2017)
Plasmid stability can be measured using antibiotic-resistance plasmid derivatives by positive selection. However, highly stable plasmids are below the sensitivity range of these assays. To solve this problem we describe a novel, highly sensitive meth
Externí odkaz:
https://doaj.org/article/c11a98c0944c4cb387df79ad0e32c1b6
Autor:
Damián Lobato-Márquez, Laura Molina-García, Inma Moreno-Córdoba, Francisco García-del Portillo, Ramón Díaz-Orejas
Publikováno v:
Frontiers in Molecular Biosciences, Vol 3 (2016)
Certain Salmonella enterica serovars belonging to subspecies I carry low-copy-number virulence plasmids of variable size (50-90 kb). All of these plasmids share the spv operon, which is important for systemic infection. Virulence plasmids are present
Externí odkaz:
https://doaj.org/article/ae61e5187f2e462995150fc526152aef
Autor:
Sammy El-Mansi, Christopher L. Robinson, Katja B. Kostelnik, Jessica J. McCormack, Tom P. Mitchell, Damián Lobato-Márquez, Vinothini Rajeeve, Pedro Cutillas, Daniel F. Cutler, Serge Mostowy, Thomas D. Nightingale
Publikováno v:
Blood.
In response to tissue injury, within seconds the ultra-large glycoprotein von Willebrand factor (VWF) is released from endothelial storage organelles (Weibel−Palade bodies) into the lumen of the blood vasculature, where it leads to the recruitment