Nonclinical pharmacokinetics and biodistribution of VSV-GP using methods to decouple input drug disposition and viral replication.

Autor: Dambra R; Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA.; Drexel University School of Biomedical Engineering, Science and Health Systems, Philadelphia, PA 19104, USA., Matter A; Nonclinical Drug Safety, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA., Graca K; Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA., Akhand SS; Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA., Mehta S; Nonclinical Drug Safety, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA., Bell-Cohn A; Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA., Swenson JM; Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA., Abid S; Material and Analytical Sciences, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA., Xin D; Material and Analytical Sciences, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA., Lewis C; Nonclinical Drug Safety, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA., Coyle L; Nonclinical Drug Safety, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA., Wang M; Nonclinical Drug Safety, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA., Bunosso K; Nonclinical Drug Safety, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA., Maugiri M; Nonclinical Drug Safety, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA., Ruiz R; Nonclinical Drug Safety, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA., Cirillo CM; Nonclinical Drug Safety, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA., Fogal B; Nonclinical Drug Safety, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA., Grimaldi C; Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA., Vigil A; Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA., Wood C; Nonclinical Drug Safety, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA., Ashour J; Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA.

Publikováno v: Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2022 Dec 28; Vol. 28, pp. 190-207. Date of Electronic Publication: 2022 Dec 28 (Print Publication: 2023).

Centyrin ligands for extrahepatic delivery of siRNA.

Autor: Klein D; Janssen Pharmaceuticals, Spring House, PA, USA. Electronic address: dklein30@its.jnj.com., Goldberg S; Janssen Pharmaceuticals, Spring House, PA, USA., Theile CS; Alnylam, Cambridge, MA, USA., Dambra R; Janssen Pharmaceuticals, Spring House, PA, USA., Haskell K; Janssen Pharmaceuticals, Spring House, PA, USA., Kuhar E; Janssen Pharmaceuticals, Spring House, PA, USA., Lin T; Janssen Pharmaceuticals, Spring House, PA, USA., Parmar R; Alnylam, Cambridge, MA, USA., Manoharan M; Alnylam, Cambridge, MA, USA., Richter M; Janssen Pharmaceuticals, Spring House, PA, USA., Wu M; Janssen Pharmaceuticals, Spring House, PA, USA., Mendrola Zarazowski J; Janssen Pharmaceuticals, Spring House, PA, USA., Jadhav V; Alnylam, Cambridge, MA, USA., Maier MA; Alnylam, Cambridge, MA, USA., Sepp-Lorenzino L; Alnylam, Cambridge, MA, USA., O'Neil K; Janssen Pharmaceuticals, Spring House, PA, USA. Electronic address: koneil@arobiotx.com., Dudkin V; Janssen Pharmaceuticals, Spring House, PA, USA.

Publikováno v: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2021 Jun 02; Vol. 29 (6), pp. 2053-2066. Date of Electronic Publication: 2021 Feb 15.

Non-Coding RNA-Targeted Therapy: A State-of-the-Art Review.

Autor: Nappi, Francesco¹ (AUTHOR) francesconappi2@gmail.com

Publikováno v: International Journal of Molecular Sciences. Apr2024, Vol. 25 Issue 7, p3630. 36p.

Non contact underwater explosions effects on ship hulls

Autor: Cobolli, G, Figari, Massimo, Damonte, R, Dambra, R.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3710::072081dcaeb181eca8dacee4bd382237
http://hdl.handle.net/11567/202209

Characterization of the Anti-Viral and Vaccine-Specific CD8 + T Cell Composition upon Treatment with the Cancer Vaccine VSV-GP.

Autor: Hofer, Tamara, Pipperger, Lisa, Danklmaier, Sarah, Das, Krishna, Wollmann, Guido

Publikováno v: Vaccines; Aug2024, Vol. 12 Issue 8, p867, 21p