Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Damaris Lorenzo"'
Autor:
Carlos Lax, Stephen J. Mondo, Macario Osorio-Concepción, Anna Muszewska, María Corrochano-Luque, Gabriel Gutiérrez, Robert Riley, Anna Lipzen, Jie Guo, Hope Hundley, Mojgan Amirebrahimi, Vivian Ng, Damaris Lorenzo-Gutiérrez, Ulrike Binder, Junhuan Yang, Yuanda Song, David Cánovas, Eusebio Navarro, Michael Freitag, Toni Gabaldón, Igor V. Grigoriev, Luis M. Corrochano, Francisco E. Nicolás, Victoriano Garre
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract DNA N6-adenine methylation (6mA) has recently gained importance as an epigenetic modification in eukaryotes. Its function in lineages with high levels, such as early-diverging fungi (EDF), is of particular interest. Here, we investigated the
Externí odkaz:
https://doaj.org/article/5354efd64f494f7582161cf6fc97112e
Autor:
Macario Osorio-Concepción, Carlos Lax, Damaris Lorenzo-Gutiérrez, José Tomás Cánovas-Márquez, Ghizlane Tahiri, Eusebio Navarro, Ulrike Binder, Francisco Esteban Nicolás, Victoriano Garre
Publikováno v:
IMA Fungus, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Mucorales are basal fungi that opportunistically cause a potentially fatal infection known as mucormycosis (black fungus disease), which poses a significant threat to human health due to its high mortality rate and its recent association wit
Externí odkaz:
https://doaj.org/article/b9f413d3edd7414bab1b37a7c36dfcb4
Autor:
Damaris Lorenzo-Gutiérrez, Lucía Gómez-Gil, Josep Guarro, M. Isabel G. Roncero, Javier Capilla, Loida López-Fernández
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 1108-1121 (2020)
Cu is an essential trace element for cell growth and proliferation. However, excess of Cu accumulation leads to cellular toxicity. Thus, precise and tight regulation of Cu homeostasis processes, including transport, delivery, storage, detoxification,
Externí odkaz:
https://doaj.org/article/2aa5659f50f14c189e867443002abfcf
Autor:
Guillermo Quindós, Katherine Miranda-Cadena, Rosario San-Millán, Katyna Borroto-Esoda, Emilia Cantón, María José Linares-Sicilia, Axel Hamprecht, Isabel Montesinos, Anna Maria Tortorano, Anna Prigitano, Matxalen Vidal-García, Cristina Marcos-Arias, Andrea Guridi, Ferran Sanchez-Reus, Jesús Machuca-Bárcena, Manuel Antonio Rodríguez-Iglesias, Estrella Martín-Mazuelos, Carmen Castro-Méndez, Leyre López-Soria, Alba Ruiz-Gaitán, Marcelo Fernandez-Rivero, Damaris Lorenzo, Javier Capilla, Antonio Rezusta, Javier Pemán, Josep Guarro, Joana Pereira, Célia Pais, Orazio Romeo, Guillermo Ezpeleta, Nerea Jauregizar, David Angulo, Elena Eraso
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
BackgroundIbrexafungerp (SCY-078) is the newest oral and intravenous antifungal drug with broad activity, currently undergoing clinical trials for invasive candidiasis.ObjectiveThe aim of this study was to assess the in vitro activity of ibrexafunger
Externí odkaz:
https://doaj.org/article/e8acd3ce6c82467e841c39ae806f8221
Autor:
Guisheng Zhong, Jiang He, Ruobo Zhou, Damaris Lorenzo, Hazen P Babcock, Vann Bennett, Xiaowei Zhuang
Publikováno v:
eLife, Vol 3 (2014)
Actin, spectrin, and associated molecules form a periodic sub-membrane lattice structure in axons. How this membrane skeleton is developed and why it preferentially forms in axons are unknown. Here, we studied the developmental mechanism of this latt
Externí odkaz:
https://doaj.org/article/93e491f51f9a4d62b83197bc780ce54f
Publikováno v:
Diabetes. 71
Impaired insulin secretion contributes to the development and progression of diabetes. β-cells initially cope with the genetic, environmental, and diabetogenic stresses that diminish insulin secretion or the peripheral response to it by increasing i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4755cec5a56b048653b1ada69d9584b
https://doi.org/10.2337/db22-245-lb
https://doi.org/10.2337/db22-245-lb
Publikováno v:
Diabetes. 71
Genetic variants in ANK2, encoding ankyrin-B (AnkB) , increase risk of obesity and type 2 diabetes in humans. We previously concluded that AnkB deficiency in white (WAT) and brown (BAT) adipose tissue (AT) of mice (AT-AnkB KO) led to lipotoxicity, WA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f71fae3d380fa1f514128a632b4acaf7
https://doi.org/10.2337/db22-313-or
https://doi.org/10.2337/db22-313-or
Autor:
M. Isabel G. Roncero, Javier Capilla, Damaris Lorenzo-Gutiérrez, Josep Guarro, Loida López-Fernández, Lucía Gómez-Gil
Publikováno v:
Virulence
article-version (VoR) Version of Record
Virulence, Vol 11, Iss 1, Pp 1108-1121 (2020)
article-version (VoR) Version of Record
Virulence, Vol 11, Iss 1, Pp 1108-1121 (2020)
Cu is an essential trace element for cell growth and proliferation. However, excess of Cu accumulation leads to cellular toxicity. Thus, precise and tight regulation of Cu homeostasis processes, including transport, delivery, storage, detoxification,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd72c5dfaf900e8e194b2ad2fce20714
http://europepmc.org/articles/PMC7549990
http://europepmc.org/articles/PMC7549990
Publikováno v:
Diabetes. 70
Human variants in the membrane adaptor ankyrin-B (AnkB) present at frequencies from 0.05 to 7% across different ethnicities have been linked to obesity and type 2 diabetes (T2D). We reported that knock-in mice bearing T2D-linked human AnkB variants d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36d578a0c724e9f741965868dbe0f43f
https://doi.org/10.2337/db21-119-or
https://doi.org/10.2337/db21-119-or
Autor:
Francisco E. Nicolás, Sergio López-García, Damaris Lorenzo-Gutiérrez, José T Cánovas-Márquez, Carlos Lax, Carlos Pérez-Arques, María Isabel Navarro-Mendoza, Victoriano Garre, Ghizlane Tahiri, Silvia Calo, Eusebio Navarro, Laura Murcia-Flores, José Antonio Pérez-Ruiz
Publikováno v:
Genes, Vol 12, Iss 586, p 586 (2021)
DIGITUM. Depósito Digital Institucional de la Universidad de Murcia
instname
Genes
Cánovas Márquez, José Tomás Navarro Mendoza, María Isabel Pérez Arques, Carlos Lax Molina, Carlos Tahiri, Ghizlane Pérez Ruiz, José Antonio Lorenzo Gutiérrez, Damaris Calo, Silvia López-García, Sergio Navarro, Eusebio Nicolás, Francisco Esteban Garre, Victoriano Murcia Flores, Laura 2021 Role of the Non-Canonical RNAi Pathway in the Antifungal Resistance and Virulence of Mucorales Genes
RODERIC. Repositorio Institucional de la Universitat de Valéncia
DIGITUM. Depósito Digital Institucional de la Universidad de Murcia
instname
Genes
Cánovas Márquez, José Tomás Navarro Mendoza, María Isabel Pérez Arques, Carlos Lax Molina, Carlos Tahiri, Ghizlane Pérez Ruiz, José Antonio Lorenzo Gutiérrez, Damaris Calo, Silvia López-García, Sergio Navarro, Eusebio Nicolás, Francisco Esteban Garre, Victoriano Murcia Flores, Laura 2021 Role of the Non-Canonical RNAi Pathway in the Antifungal Resistance and Virulence of Mucorales Genes
RODERIC. Repositorio Institucional de la Universitat de Valéncia
Mucorales are the causal agents for the lethal disease known as mucormycosis. Mortality rates of mucormycosis can reach up to 90%, due to the mucoralean antifungal drug resistance and the lack of effective therapies. A concerning urgency among the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1c10b75949d8c2589d9fd00167dc393
https://www.mdpi.com/2073-4425/12/4/586
https://www.mdpi.com/2073-4425/12/4/586