Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Daluthgamage Patsy H Wijesekera"'
Autor:
Nadeeka H De Silva, Takashi Akazawa, Viskam Wijewardana, Norimitsu Inoue, Maremichi Oyamada, Atsuko Ohta, Yuki Tachibana, Daluthgamage Patsy H Wijesekera, Mitsuru Kuwamura, Yasuko Nishizawa, Kazuyuki Itoh, Takeshi Izawa, Shingo Hatoya, Tetsuya Hasegawa, Jyoji Yamate, Toshio Inaba, Kikuya Sugiura
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188738 (2017)
Although dendritic cell (DC)-based immunotherapy shows little toxicity, improvements should be necessary to obtain satisfactory clinical outcome. Using interferon-gamma injection along with DCs, we previously obtained significant clinical responses a
Externí odkaz:
https://doaj.org/article/1d3dc6a1bf854751b06088d606d6cb0e
Autor:
Daluthgamage Patsy H. Wijesekera, Ryoji Kanegi, Kikuya Sugiura, Shingo Hatoya, Noritoshi Kawate, Naoya Unezaki, Toshio Inaba, Hiromichi Tamada, Hiroshi Imai, Toshiya Nishimura
Publikováno v:
Stem Cells and Development. 26:1111-1120
Extraembryonic endoderm (XEN) cells are stem cell lines derived from primitive endoderm cells of inner cell mass in blastocysts. These cells have self-renewal properties and differentiate into visceral endoderm (VE) and parietal endoderm (PE) of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddb41264061bbc2e737bd95172e2a185
https://doi.org/10.1089/scd.2017.0026
https://doi.org/10.1089/scd.2017.0026
Autor:
Chihiro Ichida, Masaya Tsukamoto, Ryoji Kanegi, Kikuya Sugiura, Shun‐ichi Watanabe, Daluthgamage Patsy H. Wijesekera, Nadeeka Harshini De Silva, Kazuyuki Itoh, Jyoji Yamate, Eiji Yuba, Takeshi Izawa, Shingo Hatoya, Toshio Inaba
Publikováno v:
FASEB bioAdvances
FASEB BioAdvances, Vol 2, Iss 1, Pp 5-17 (2020)
FASEB BioAdvances, Vol 2, Iss 1, Pp 5-17 (2020)
The tumor microenvironment strongly influences clinical outcomes of immunotherapy. By transfecting genes of relevant cytokines into tumor cells, we sought to manipulate the microenvironment so as to elicit activation of T helper type 1 (Th1) response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1331a95e1069a05ed89a0797bc5782
https://pubmed.ncbi.nlm.nih.gov/32123853
https://pubmed.ncbi.nlm.nih.gov/32123853
Autor:
Yuki Tachibana, Takashi Akazawa, Kikuya Sugiura, Jyoji Yamate, Takeshi Izawa, Mitsuru Kuwamura, Daluthgamage Patsy H. Wijesekera, Toshio Inaba, Nadeeka Harshini De Silva, Atsuko Ohta, Maremichi Oyamada, Yasuko Nishizawa, Tetsuya Hasegawa, Kazuyuki Itoh, Viskam Wijewardana, Norimitsu Inoue, Shingo Hatoya
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 11, p e0188738 (2017)
PLoS ONE, Vol 12, Iss 11, p e0188738 (2017)
Although dendritic cell (DC)-based immunotherapy shows little toxicity, improvements should be necessary to obtain satisfactory clinical outcome. Using interferon-gamma injection along with DCs, we previously obtained significant clinical responses a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca822d56d7132e3a7816c752252bf83
http://europepmc.org/articles/PMC5708771
http://europepmc.org/articles/PMC5708771
Autor:
Kenji Kono, Eiji Yuba, Kana Ueda, Takahiro Ushigusa, Toshio Inaba, Shingo Hatoya, Daluthgamage Patsy H. Wijesekera, Ryouji Kanegi, Viskam Wijewardana, Toshiya Nishimura, Kikuya Sugiura
Publikováno v:
Veterinary Immunology and Immunopathology. 162:59-64
The existence of Th1 responses in a tumor microenvironment elicits a better prognosis for the patients. Transfection of Th1 polarizing cytokines, such as IFNγ, into tumor cells is an effective way to set up an appropriate microenvironment. Using a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a77eda2f11f83c488cb480901ec63e0
https://doi.org/10.1016/j.vetimm.2014.08.016
https://doi.org/10.1016/j.vetimm.2014.08.016
Autor:
Daluthgamage Patsy H. Wijesekera, Ryoji Kanegi, Takahiro Ushigusa, Shingo Hatoya, Toshio Inaba, Viskam Wijewardana, Toshiya Nishimura, Kikuya Sugiura
Publikováno v:
The Journal of Veterinary Medical Science
Previously, we reported that ovarian hormones affect the immune response against E. coli isolated from the dogs affected with pyometra. In order to investigate mechanisms underlying the immune modulation, we examined the effects of ovarian hormones o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abacb7cf6015fb2a7e6450059fae1dc6
https://pubmed.ncbi.nlm.nih.gov/25715707
https://pubmed.ncbi.nlm.nih.gov/25715707
Autor:
Shingo Hatoya, Norimitsu Inoue, Daluthgamage Patsy H. Wijesekera, Takashi Akazawa, Kikuya Sugiura, Viskam Wijewardana, Shigeki Imamoto, Toshio Inaba, Mana Yahata
Publikováno v:
Veterinary immunology and immunopathology. 156(1-2)
CD40 ligand (CD40L) expressed by activated T cells is shown to induce maturation of immature dendritic cells (DCs) and this maturation is a vital part in DC based tumor immunotherapy. We constructed an expression vector by cloning the extracellular d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9dd07bd44e55ab13932baaa91bac3b0
https://pubmed.ncbi.nlm.nih.gov/24144681
https://pubmed.ncbi.nlm.nih.gov/24144681
Effect of ovarian hormones on maturation of dendritic cells from peripheral blood monocytes in dogs.
Autor:
Viskam WIJEWARDANA, Kikuya SUGIURA, Daluthgamage Patsy H. WIJESEKERA, Shingo HATOYA, Toshiya NISHIMURA, Ryoji KANEGI, Takahiro USHIGUSA, Toshio INABA
Publikováno v:
Journal of Veterinary Medical Science; Jul2015, Vol. 77 Issue 7, p771-775, 5p