Výsledky vyhledávání - "Daltry L. Snider"

Akademický článek

RNA modification of an RNA modifier prevents self-RNA sensing.

Publikováno v: PLoS Biology, Vol 19, Iss 7, p e3001342 (2021)

A new study in PLOS Biology finds that interferon (IFN)-induced adenosine deaminase acting on RNA 1 (ADAR1) mRNA is N6-methyladenosine (m6A) modified to promote its translation, enabling ADAR1 to modify self-double-stranded RNAs (dsRNAs) generated du

Externí odkaz: https://doaj.org/article/c8b38f4da6e049d283c2654527223c7d

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Akademický článek

The mRNA Cap 2′-O-Methyltransferase CMTR1 Regulates the Expression of Certain Interferon-Stimulated Genes

Autor: Graham D. Williams, Nandan S. Gokhale, Daltry L. Snider, Stacy M. Horner

Publikováno v: mSphere, Vol 5, Iss 3 (2020)

ABSTRACT Type I interferons (IFN) initiate an antiviral state through a signal transduction cascade that leads to the induction of hundreds of IFN-stimulated genes (ISGs) to restrict viral infection. Recently, RNA modifications on both host and viral

Externí odkaz: https://doaj.org/article/03799356559a46dd974db83f9190f76f

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Signaling from the RNA sensor RIG-I is regulated by ufmylation

Autor: Dia C. Beachboard, Stacy M. Horner, Moonhee Park, Daltry L. Snider, Kristen A. Murphy

Publikováno v: Proceedings of the National Academy of Sciences. 119

The RNA binding protein RIG-I is a key initiator of the antiviral innate immune response. The signaling that mediates the antiviral response downstream of RIG-I is transduced through the adaptor protein MAVS and results in the induction of type I and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6903eaea8fdae3c241825e2e1d7b7cb8
https://doi.org/10.1073/pnas.2119531119

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The small GTPase RAB1B promotes antiviral innate immunity by interacting with TNF receptor–associated factor 3 (TRAF3)

Autor: Dia C. Beachboard, Daltry L. Snider, Madhuvanthi Vijayan, Michael J. McFadden, Sydney Stanley, Stacy M. Horner, Dillon J. Fernando, Graham D. Williams, Moonhee Park

Publikováno v: J Biol Chem

Innate immune detection of viral nucleic acids during viral infection activates a signaling cascade that induces type I and type III IFNs as well as other cytokines, to generate an antiviral response. This signaling is initiated by pattern recognitio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed9d49af40f9ab027ddd8c1e1d17836
https://doi.org/10.1074/jbc.ra119.007917

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The mRNA Cap 2′- O -Methyltransferase CMTR1 Regulates the Expression of Certain Interferon-Stimulated Genes

Autor: Daltry L. Snider, Stacy M. Horner, Graham D. Williams, Nandan S. Gokhale

Publikováno v: mSphere, Vol 5, Iss 3 (2020)
mSphere, Vol 5, Iss 3, p e00202-20 (2020)

Type I interferons (IFN) initiate an antiviral state through a signal transduction cascade that leads to the induction of hundreds of IFN-stimulated genes (ISGs) to restrict viral infection. Recently, RNA modifications on both host and viral RNAs hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3316bc3bcbaeca379170d8376df4209
https://doi.org/10.1128/msphere.00202-20

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