Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Dalong Qian"'
Autor:
Linda J. vanWeele, Sabra I. Djomehri, Shang Cai, Jane Antony, Shaheen S. Sikandar, Dalong Qian, William H. D. Ho, Robert B. West, Ferenc A. Scheeren, Michael F. Clarke
Publikováno v:
Molecular Oncology, Vol 16, Iss 17, Pp 3128-3145 (2022)
As precision medicine increases the response rate of treatment, tumors frequently bypass inhibition, and reoccur. In order for treatment to be effective long term, the mechanisms enabling treatment adaptation need to be understood. Here, we report a
Externí odkaz:
https://doaj.org/article/8d6bdff9fa234733908de5b2990ded0f
Autor:
Felicia Reinitz, Elizabeth Y Chen, Benedetta Nicolis di Robilant, Bayarsaikhan Chuluun, Jane Antony, Robert C Jones, Neha Gubbi, Karen Lee, William Hai Dang Ho, Sai Saroja Kolluru, Dalong Qian, Maddalena Adorno, Katja Piltti, Aileen Anderson, Michelle Monje, H Craig Heller, Stephen R Quake, Michael F Clarke
Publikováno v:
eLife, Vol 11 (2022)
Alzheimer’s disease (AD) is a progressive neurodegenerative disease observed with aging that represents the most common form of dementia. To date, therapies targeting end-stage disease plaques, tangles, or inflammation have limited efficacy. Theref
Externí odkaz:
https://doaj.org/article/92c5abc287934048bbc8abb6eae7052f
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-8 (2018)
Abstract Background Recent studies in murine mammary tissue have identified functionally distinct cell populations that may be isolated by surface phenotype or lineage tracing. Previous groups have shown that CD24medCD49fhigh cells enriched for long-
Externí odkaz:
https://doaj.org/article/72dd897acabf4d08bc28d6807e5592bd
Autor:
Shaheen S. Sikandar, Angera H. Kuo, Tomer Kalisky, Shang Cai, Maider Zabala, Robert W. Hsieh, Neethan A. Lobo, Ferenc A. Scheeren, Sopheak Sim, Dalong Qian, Frederick M. Dirbas, George Somlo, Stephen R. Quake, Michael F. Clarke
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
The contribution of EMT in mammary gland homeostasis and human breast cancer is still unclear. Here, using in vivo lineage tracing and breast cancer PDXs the authors demonstrate that the repopulating capacity in normal mammary epithelial cells and tu
Externí odkaz:
https://doaj.org/article/f0f50f3b3e2d42029e585ebb81c7168c
Autor:
Taichi Isobe, Shigeo Hisamori, Daniel J Hogan, Maider Zabala, David G Hendrickson, Piero Dalerba, Shang Cai, Ferenc Scheeren, Angera H Kuo, Shaheen S Sikandar, Jessica S Lam, Dalong Qian, Frederick M Dirbas, George Somlo, Kaiqin Lao, Patrick O Brown, Michael F Clarke, Yohei Shimono
Publikováno v:
eLife, Vol 3 (2014)
MicroRNAs (miRNAs) are important regulators of stem and progenitor cell functions. We previously reported that miR-142 and miR-150 are upregulated in human breast cancer stem cells (BCSCs) as compared to the non-tumorigenic breast cancer cells. In th
Externí odkaz:
https://doaj.org/article/12df545b9b7f407281bc82e145ae3c9e
Autor:
Raj. S. Mitra, Mary A. Benedict, Dalong Qian, Kimberly E. Foreman, Daryoush Ekhterae, Brian J. Nickoloff, Gabriel Nuñez
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 5, Pp 437-445 (2001)
Kaposi's sarcoma (KS) is the most common tumor affecting AIDS patients with over 20% of these patients afflicted by this disease. Previous studies have demonstrated that KS tumor cells predominantly express the prosurvival protein Bcl-XL compared wit
Externí odkaz:
https://doaj.org/article/44e849354f90457f91e994585607b5bc
Autor:
Shigeo Hisamori, Junko Mukohyama, Sanjay Koul, Takanori Hayashi, Michael Evan Rothenberg, Masao Maeda, Taichi Isobe, Luis Enrique Valencia Salazar, Xin Qian, Darius Michael Johnston, Dalong Qian, Kaiqin Lao, Naoya Asai, Yoshihiro Kakeji, Vincenzo Alessandro Gennarino, Debashis Sahoo, Piero Dalerba, Yohei Shimono
Publikováno v:
J Gastroenterol
BACKGROUND: MicroRNAs (miRNAs) are key regulators of stem cell functions, including self-renewal and differentiation. In this study, we aimed to identify miRNAs that are up-regulated during terminal differentiation in the human colon epithelium, and
Autor:
Shaheen S. Sikandar, Gunsagar S. Gulati, Jane Antony, Isobel Fetter, Angera H. Kuo, William Hai Dang Ho, Veronica Haro-Acosta, Soumyashree Das, Chloé B. Steen, Thiago Almeida Pereira, Dalong Qian, Philip A. Beachy, Fredrick Dirbas, Kristy Red-Horse, Terence H. Rabbitts, Jean Paul Thiery, Aaron M. Newman, Michael F. Clarke
Publikováno v:
Science Advances. 8
Metastasis is responsible for most breast cancer–related deaths; however, identifying the cellular determinants of metastasis has remained challenging. Here, we identified a minority population of immatureTHY1+/VEGFA+tumor epithelial cells in human
Autor:
Shang Cai, Dalong Qian, Michael F. Clarke, William H.D. Ho, Angera H. Kuo, Linda J. van Weele, Ferenc A. Scheeren
Publikováno v:
Stem Cell Reports, 16(2), 228-236. ELSEVIER
Stem Cell Reports
Stem Cell Reports
Summary The mammary epithelium undergoes several rounds of extensive proliferation during the female reproductive cycle. Its expansion is a tightly regulated process, fueled by the mammary stem cells and these cells' unique property of self-renewal.
Autor:
Benedetta Nicolis di Robilant, Elizabeth Y Chen, Felicia Reinitz, Bayarsaikhan Chuluun, Jane Antony, Robert C Jones, Neha Gubbi, Karen Lee, William Hai Dang Ho, Sai Saroja Kolluru, Dalong Qian, Maddalena Adorno, Katja Piltti, Aileen Anderson, Michelle Monje, H Craig Heller, Stephen R Quake, Michael F Clarke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c06b69fb3ac0c75f6f4029ed4b8b982
https://doi.org/10.7554/elife.66037.sa2
https://doi.org/10.7554/elife.66037.sa2