Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Dallin Milner"'
Autor:
Sana D. Karam, Elena B. Pasquale, Eric T. Clambey, Antonio Jimeno, Xiao-Jing Wang, Natalie J. Serkova, David Raben, Benjamin Van Court, Adam C. Mueller, Andy V. Phan, Dallin Milner, Laurel B. Darragh, Shelby Lennon, Ayman Oweida, Shilpa Bhatia
Mice implanted with PDX tumors show significantly reduced uptake of supra-paramagnetic iron oxide nanoparticles (SPIO) in the combined sEphB4-HSA and RT group compared to the groups treated with RT alone or with sEphB4-HSA alone in DCE-MRI imaging (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f40e96ae3a2c0a71d4425ecd0cdc09bd
https://doi.org/10.1158/0008-5472.22418520.v1
https://doi.org/10.1158/0008-5472.22418520.v1
Autor:
Sana D. Karam, Elena B. Pasquale, Eric T. Clambey, Antonio Jimeno, Xiao-Jing Wang, Natalie J. Serkova, David Raben, Benjamin Van Court, Adam C. Mueller, Andy V. Phan, Dallin Milner, Laurel B. Darragh, Shelby Lennon, Ayman Oweida, Shilpa Bhatia
Immunofluorescence staining showing co-expression of EphB4 and pan-keratin in Ly2 tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9472c5e39fe6656ff7396b0c200fd318
https://doi.org/10.1158/0008-5472.22418541
https://doi.org/10.1158/0008-5472.22418541
Autor:
Sana D. Karam, Elena B. Pasquale, Eric T. Clambey, Antonio Jimeno, Xiao-Jing Wang, Natalie J. Serkova, David Raben, Benjamin Van Court, Adam C. Mueller, Andy V. Phan, Dallin Milner, Laurel B. Darragh, Shelby Lennon, Ayman Oweida, Shilpa Bhatia
IHC staining confirming expression of ephrin-B2 in areas stained with fibroblast-expressing α-Smooth muscle actin (α-SMA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67afcb005592eb6d766d5fd4291f1515
https://doi.org/10.1158/0008-5472.22418538.v1
https://doi.org/10.1158/0008-5472.22418538.v1
Autor:
Sana D. Karam, Elena B. Pasquale, Eric T. Clambey, Antonio Jimeno, Xiao-Jing Wang, Natalie J. Serkova, David Raben, Benjamin Van Court, Adam C. Mueller, Andy V. Phan, Dallin Milner, Laurel B. Darragh, Shelby Lennon, Ayman Oweida, Shilpa Bhatia
Blockade of EphB4-ephrin-B2 interaction combined with RT suppresses tumor growth in HNSCC tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580152e3bfb523bc3b498a5942f601c4
https://doi.org/10.1158/0008-5472.22418523
https://doi.org/10.1158/0008-5472.22418523
Autor:
Sana D. Karam, Lynn Heasley, Hilary Somerset, David Raben, Antonio Jimeno, Nomin Uyanga, Dallin Milner, Andy Phan, Shelby Lennon, Ayman Oweida, Sanjana Bukkapatnam, Jaspreet Sharma, Shilpa Bhatia
Blockade of EphB4-ephrin-B2 enhances response to EGFR inhibitor (cetuximab) and RT resulting in significant delay in tumor growth and enhanced survival in HNSCC PDX models. Tumor growth volumes are displayed in CUHN013 (A) and CUHN004 (B) tumors incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ef75a5201398cd276c7ddfdbc01db5
https://doi.org/10.1158/1078-0432.22470825.v1
https://doi.org/10.1158/1078-0432.22470825.v1
Autor:
Sana D. Karam, Elena B. Pasquale, Eric T. Clambey, Antonio Jimeno, Xiao-Jing Wang, Natalie J. Serkova, David Raben, Benjamin Van Court, Adam C. Mueller, Andy V. Phan, Dallin Milner, Laurel B. Darragh, Shelby Lennon, Ayman Oweida, Shilpa Bhatia
(A) ELISA assay measuring the concentration of TNYL-RAW-Fc protein in plasma 7 days after hydrodynamic injection of the TNYL-RAW-Fc plasmid. Data represent mean {plus minus} SD from measurements using different mice (n=2). (B) Inhibition of EphB4-eph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53170a91cb748ecd1e8c5e25959956ae
https://doi.org/10.1158/0008-5472.22418532
https://doi.org/10.1158/0008-5472.22418532
Autor:
Sana D. Karam, Elena B. Pasquale, Eric T. Clambey, Antonio Jimeno, Xiao-Jing Wang, Natalie J. Serkova, David Raben, Benjamin Van Court, Adam C. Mueller, Andy V. Phan, Dallin Milner, Laurel B. Darragh, Shelby Lennon, Ayman Oweida, Shilpa Bhatia
qPCR analysis shows elevated expression of EphB4 on intratumoral macrophages harvested from Ly2 tumors compared to ephrin-B2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30d61a658c40cfb9d8421fb4eaa73f30
https://doi.org/10.1158/0008-5472.22418535.v1
https://doi.org/10.1158/0008-5472.22418535.v1
Autor:
Sana D. Karam, Elena B. Pasquale, Eric T. Clambey, Antonio Jimeno, Xiao-Jing Wang, Natalie J. Serkova, David Raben, Benjamin Van Court, Adam C. Mueller, Andy V. Phan, Dallin Milner, Laurel B. Darragh, Shelby Lennon, Ayman Oweida, Shilpa Bhatia
Systemic depletion of CD8+ T cells results in increased tumor growth in Ly2 tumors treated with TNYL-RAW-Fc (A). Confirmation of CD8+ T cell depletion by flow cytometry (B). Student's t-test or one-way ANOVA was used to calculate the significance of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3265c2455c11f52d7950450a6b676adf
https://doi.org/10.1158/0008-5472.22418529
https://doi.org/10.1158/0008-5472.22418529
Autor:
Sana D. Karam, Elena B. Pasquale, Eric T. Clambey, Antonio Jimeno, Xiao-Jing Wang, Natalie J. Serkova, David Raben, Benjamin Van Court, Adam C. Mueller, Andy V. Phan, Dallin Milner, Laurel B. Darragh, Shelby Lennon, Ayman Oweida, Shilpa Bhatia
Total number of CD4+T cells remain unchanged following Control-Fc and ephrin-B2-Fc (20 μg/ml) treatment of T cells (A). Correlation analysis was also performed between TGF-β and EFNB2, EphB4 on R2 analysis platform (B-C). Alterations of cell growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6078b77d89ee423be4cb90645ba5b3b4
https://doi.org/10.1158/0008-5472.22418526.v1
https://doi.org/10.1158/0008-5472.22418526.v1
Autor:
Sana D. Karam, Lynn Heasley, Hilary Somerset, David Raben, Antonio Jimeno, Nomin Uyanga, Dallin Milner, Andy Phan, Shelby Lennon, Ayman Oweida, Sanjana Bukkapatnam, Jaspreet Sharma, Shilpa Bhatia
Levels of EGFR expression in HNSCC PDX tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea203d6c376d65503a534783cbf3914
https://doi.org/10.1158/1078-0432.22470828.v1
https://doi.org/10.1158/1078-0432.22470828.v1