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Synthesis of diversely substituted pyridin-2(1H)-ones and in vivo evaluation of their anti-allodynic effect on cutaneous inflammatory mechanical allodynia.

Autor: Frazier, Théo, Murail, Pauline, Boulangé, Arthur, Chalane, Nazim, Giraud, Francis, Artola, Alain, Dallel, Radhouane, Anizon, Fabrice, Moreau, Pascale

Publikováno v: RSC Medicinal Chemistry; Aug2024, Vol. 15 Issue 8, p2900-2921, 22p

Pyridin-2(1H)one derivatives: A possible new class of therapeutics for mechanical allodynia

Autor: Visseq, Alexia, Descheemaeker, Amélie, Pinto-Pardo, Nicolas, Nauton, Lionel, Théry, Vincent, Giraud, Francis, Abrunhosa-Thomas, Isabelle, Artola, Alain, Anizon, Fabrice, Dallel, Radhouane, Moreau, Pascale

Publikováno v: In European Journal of Medicinal Chemistry 1 February 2020 187

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Chronic facial inflammatory pain-induced anxiety is associated with bilateral deactivation of the rostral anterior cingulate cortex

Autor: Ducret, Eric, Jacquot, Florian, Descheemaeker, Amélie, Dallel, Radhouane, Artola, Alain

Publikováno v: Brain Research Bulletin
Brain Research Bulletin, Elsevier, 2022, 184, pp.88-98. ⟨10.1016/j.brainresbull.2022.03.012⟩
Brain Research Bulletin, 2022, 184, pp.88-98. ⟨10.1016/j.brainresbull.2022.03.012⟩

International audience; Patients with chronic pain, especially orofacial pain, often suffer from affective disorders, including anxiety. Previous studies largely focused on the role of the caudal anterior cingulate cortex (cACC) in affective response

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be7854644486daae6f34292fa1179a4
https://doi.org/10.1016/j.brainresbull.2022.03.012