Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Dallas M. Rohraff"'
Autor:
Sirapa Vichaikul, Mikel Gurrea-Rubio, M. Asif Amin, Phillip L. Campbell, Qi Wu, Megan N. Mattichak, William D. Brodie, Pamela J. Palisoc, Mustafa Ali, Sei Muraoka, Jeffrey H. Ruth, Ellen N. Model, Dallas M. Rohraff, Jonatan L. Hervoso, Yang Mao-Draayer, David A. Fox, Dinesh Khanna, Amr H. Sawalha, Pei-Suen Tsou
Publikováno v:
JCI Insight, Vol 7, Iss 9 (2022)
Binding of the bromodomain and extraterminal domain proteins (BETs) to acetylated histone residues is critical for gene transcription. We sought to determine the antifibrotic efficacy and potential mechanisms of BET inhibition in systemic sclerosis (
Externí odkaz:
https://doaj.org/article/144c5e7d2e6a41519ccf4095bccbb0c0
Autor:
Christine Marie Kava, Dallas M. Rohraff, Bailey Wallace, Jennifer L. Mendoza-Alonzo, Dustin W. Currie, Anna E. Munsey, Nicole M. Roth, Jonathan Bryant-Genevier, Jordan L. Kennedy, Daniel L. Weller, Athalia Christie, Jennifer H. McQuiston, Peter Hicks, Penelope Strid, Emily Sims, Maria E. Negron, Kashif Iqbal, Sascha Ellington, Dawn K. Smith
Publikováno v:
MMWR. Morbidity and Mortality Weekly Report. 71:1449-1456
On May 17, 2022, the Massachusetts Department of Health announced the first suspected case of monkeypox associated with the global outbreak in a U.S. resident. On May 23, 2022, CDC launched an emergency response (1,2). CDC's emergency response focuse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0bdb33acf2f732b486f227c2e4e2050
https://doi.org/10.15585/mmwr.mm7145a4
https://doi.org/10.15585/mmwr.mm7145a4
Autor:
Amr H. Sawalha, Shaylynn Miller, Patrick Coit, Pei-Suen Tsou, Nathan C Kilian, Mark Schonfeld, Dallas M Rohraff, Elizabeth Gensterblum-Miller, Paul Renauer
Publikováno v:
Annals of the Rheumatic Diseases. 78:519-528
ObjectiveWe examined genome-wide DNA methylation changes in CD8+ T cells from patients with lupus and controls and investigated the functional relevance of some of these changes in lupus.MethodsGenome-wide DNA methylation of lupus and age, sex and et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::096ec35395b26f4314c7c88fe1a334c9
https://doi.org/10.1136/annrheumdis-2018-214323
https://doi.org/10.1136/annrheumdis-2018-214323
Autor:
Sirapa Vichaikul, Mikel Gurrea-Rubio, M. Asif Amin, Phillip L. Campbell, Qi Wu, Megan N. Mattichak, William D. Brodie, Pamela J. Palisoc, Mustafa Ali, Sei Muraoka, Jeffrey H. Ruth, Ellen N. Model, Dallas M. Rohraff, Jonatan L. Hervoso, Yang Mao-Draayer, David A. Fox, Dinesh Khanna, Amr H. Sawalha, Pei-Suen Tsou
Publikováno v:
JCI insight. 7(9)
Binding of the bromodomain and extraterminal domain proteins (BETs) to acetylated histone residues is critical for gene transcription. We sought to determine the antifibrotic efficacy and potential mechanisms of BET inhibition in systemic sclerosis (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2727b613a0d32eb92f4ad3c2bb91ce9
https://pubmed.ncbi.nlm.nih.gov/35349485
https://pubmed.ncbi.nlm.nih.gov/35349485
Autor:
Sirapa Vichaikul, Mikel Gurrea-Rubio, M. Asif Amin, Phillip L. Campbell, Qi Wu, Megan N. Mattichak, William D. Brodie, Pamela J. Palisoc, Mustafa Ali, Sei Muraoka, Jeffrey H. Ruth, Ellen N. Model, Dallas M. Rohraff, Jonatan L. Hervoso, Yang Mao-Draayer, David A. Fox, Dinesh Khanna, Amr H. Sawalha, Pei-Suen Tsou
ObjectivesBinding of the bromodomain and extra-terminal domain proteins (BETs) to acetylated histone residues is critical for gene transcription in many fibrotic diseases. This study sought to determine the anti-fibrotic efficacy and potential mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e93faaaa9a3ae218b509983984555a4b
https://doi.org/10.1101/2020.08.07.242198
https://doi.org/10.1101/2020.08.07.242198
Publikováno v:
Poster Presentations.
Background We previously revealed a role for EZH2 in inducing pro-inflammatory epigenetic changes in lupus CD4+ T cells. Objectives In this study, we sought to determine if inhibiting EZH2 ameliorates lupus-like disease in MRL/lpr mice. Methods EZH2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20a38685039c5affb2c935d21f83e9d0
https://doi.org/10.1136/annrheumdis-2019-eular.2503
https://doi.org/10.1136/annrheumdis-2019-eular.2503
Publikováno v:
Arthritis Rheumatol
ObjectivesWe previously revealed a role for EZH2 in inducing pro-inflammatory epigenetic changes in lupus CD4+ T cells. In this study, we sought to determine if inhibiting EZH2 ameliorates lupus-like disease in MRL/lpr mice.MethodsEZH2 expression lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f624e22e3085b9ba40ed7a2bb02563
Autor:
Shaylynn, Miller, Pei-Suen, Tsou, Patrick, Coit, Elizabeth, Gensterblum-Miller, Paul, Renauer, Dallas M, Rohraff, Nathan C, Kilian, Mark, Schonfeld, Amr H, Sawalha
Publikováno v:
Annals of the rheumatic diseases. 78(4)
OBJECTIVE: We examined genome-wide DNA methylation changes in CD8+ T cells from patients with lupus and controls and investigated the functional relevance of some of these changes in lupus. METHODS: Genome-wide DNA methylation of lupus and age, sex a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b26d0d07b1577b3a96032f2b4a623f23
https://pubmed.ncbi.nlm.nih.gov/30674474
https://pubmed.ncbi.nlm.nih.gov/30674474