Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Dallas C Jones"'
Autor:
Jochen G Hofstaetter, Barbara M Misof, Dallas C Jones, Ruth Zoehrer, Stéphane Blouin, Christiane Schueler, Eleftherios P Paschalis, Reinhold G Erben, Richard Weinkamer, Klaus Klaushofer, Paul Roschger
Publikováno v:
JBMR Plus, Vol 3, Iss 11, Pp n/a-n/a (2019)
ABSTRACT Schnurri‐3 (Shn3) is an essential regulator of postnatal skeletal remodeling. Shn3‐deficient mice (Shn3–/–) have high bone mass; however, their bone mechanical and material properties have not been investigated to date. We performed
Externí odkaz:
https://doaj.org/article/beceafcfc65d4d64a7f762c5fcb54b09
Autor:
Cristina St Pierre, Jane Guo, John D Shin, Laura W Engstrom, Hyun-Hee Lee, Alan Herbert, Laura Surdi, James Baker, Michael Salmon, Sanjiv Shah, J Michael Ellis, Hani Houshyar, Michael A Crackower, Melanie A Kleinschek, Dallas C Jones, Alexandra Hicks, Dennis M Zaller, Stephen E Alves, Ravisankar A Ramadas
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180870 (2017)
While the immune system is essential for the maintenance of the homeostasis, health and survival of humans, aberrant immune responses can lead to chronic inflammatory and autoimmune disorders. Pharmacological modulation of drug targets in the immune
Externí odkaz:
https://doaj.org/article/a511e5553a1e4c19982a055d21745012
Autor:
Dallas C. Jones, Wenguang Zheng, Sheng Huang, Chuanlong Du, Xuefeng Zhao, Ragothaman M. Yennamalli, Taner Z. Sen, Dan Nettleton, Eve Syrkin Wurtele, Ling Li
Publikováno v:
Frontiers in Plant Science, Vol 7 (2016)
Nearly immobile, plants have evolved new components to be able to respond to changing environments. One example is Qua Quine Starch (QQS, AT3G30720), an Arabidopsis thaliana-specific orphan gene that integrates primary metabolism with adaptation to e
Externí odkaz:
https://doaj.org/article/f38de6af559e431ba07996837d9c0cad
Autor:
Laura Engstrom, Kyle J. Piers, Kenneth Jay Barr, Renu Jain, Dallas C. Jones, Huseyin Mehmet, Heidi Ferguson, Gary D. Glick, John S. Mudgett, Richard Miller, Xiao Hu, Hongjun Zhang, I-Ming Wang, Abbas Hawwari, Craig C. Correll, Barbara Joyce-Shaikh, Razvan Cristescu, Yanxia Guo, Daniel J. Cua, Gretchen A. Baltus, Yi Chen, Thomas Daniel Aicher, Dennis M. Zaller, Laura L. Carter, Laxminarayan G Hegde, Kenzie D. MacIsaac
Publikováno v:
Cell Reports, Vol 17, Iss 12, Pp 3206-3218 (2016)
Recent studies have elucidated the molecular mechanism of RORγT transcriptional regulation of Th17 differentiation and function. RORγT was initially identified as a transcription factor required for thymopoiesis by maintaining survival of CD4+CD8+
Publikováno v:
Nature Cell Biology. 20:519-520
Autor:
Christiane Schueler, R. Zoehrer, Eleftherios P. Paschalis, Barbara M. Misof, Stéphane Blouin, Paul Roschger, Jochen G. Hofstaetter, Klaus Klaushofer, Richard Weinkamer, Dallas C. Jones, Reinhold G. Erben
Publikováno v:
JBMR Plus. 3:e10226
Schnurri-3 (Shn3) is an essential regulator of postnatal skeletal remodeling. Shn3-deficient mice (Shn3-/-) have high bone mass; however, their bone mechanical and material properties have not been investigated to date. We performed three-point bendi
Autor:
Sutada Lotinun, Roland Baron, Weiguo Zou, Jae-Hyuck Shim, Matthew B. Greenblatt, Dallas C. Jones, Bo Zhai, Shashi Kant, Roger J. Davis, Dorothy Hu, Laurie H. Glimcher, Steven P. Gygi, Nicholas J. Brady
Publikováno v:
Journal of Clinical Investigation. 121:4383-4392
Mutations in human FYVE, RhoGEF, and PH domain–containing 1 (FGD1) cause faciogenital dysplasia (FGDY; also known as Aarskog syndrome), an X-linked disorder that affects multiple skeletal structures. FGD1 encodes a guanine nucleotide exchange facto
Publikováno v:
Journal of Clinical Investigation. 121:2534-2542
Over the past decade and a half, the biomedical community has uncovered a previously unappreciated reciprocal relationship between cells of the immune and skeletal systems. Work in this field, which has been termed “osteoimmunology,” has resulted
Autor:
Shunsuke Ishii, Vanja Lazarevic, Laurie H. Glimcher, Tracy L. Staton, Amanda J. Lanser, Dallas C. Jones, Tsuyoshi Takagi
Publikováno v:
Nature
Generation of a diverse and self-tolerant T-cell repertoire requires appropriate interpretation of T-cell antigen receptor (TCR) signals by CD4(+ ) CD8(+) double-positive thymocytes. Thymocyte cell fate is dictated by the nature of TCR-major-histocom
Autor:
Weiguo Zou, Xi Chen, Nicholas J. Brady, Laurie H. Glimcher, Dallas C. Jones, Kirsten Sigrist, Dorothy Hu, Rebecca Drapp, Jae-Hyuck Shim, Zhiwei Huang
Publikováno v:
Nature cell biology
Craniofacial anomalies (CFAs) are the most frequently occurring human congenital disease, and a major cause of infant mortality and childhood morbidity. Although CFAs seems to arise from a combination of genetic factors and environmental influences,