Real-World Effectiveness of Upadacitinib for Treatment of Rheumatoid Arthritis in Canadian Patients: Interim Results from the Prospective Observational CLOSE-UP Study

Autor: Louis Bessette, Jonathan Chan, Andrew Chow, Larissa Lisnevskaia, Nicolas Richard, Pierre-Andre Fournier, Dalinda Liazoghli, Tanya Girard, Derek Haaland

Publikováno v: Rheumatology and Therapy, Vol 11, Iss 3, Pp 563-582 (2024)

Abstract Introduction Upadacitinib (UPA), a selective, reversible, oral Janus kinase (JAK)-1 inhibitor, was approved in 2019 in Canada for the treatment of adults with moderately to severely active rheumatoid arthritis (RA). This phase 4 prospective

Externí odkaz: https://doaj.org/article/1871a11fff06453588ea8eba2d022cb9

Atomic Force Microscopy Reveals Important Differences in Axonal Resistance to Injury

Autor: Margaret H. Magdesian, Fernando Suarez Sanchez, Nela Durisic, Peter Thostrup, Monserratt Lopez, Dalinda Liazoghli, Wiam Belkaid, David R. Colman, Peter Grutter

Publikováno v: Biophysical Journal. 103(3):405-414

Axonal degeneration after traumatic brain injury and nerve compression is considered a common underlying cause of temporary as well as permanent disability. Because a proper functioning of neural network requires phase coherence of all components, ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98d2a8c5da2fc83df313ee2636f2cfc9

A Canadian Retrospective Chart Review Evaluating Concomitant Methotrexate De-escalation Patterns in Patients with Rheumatoid Arthritis Treated with Biologic or Targeted Synthetic DMARDs.

Autor: Bessette, Louis¹ (AUTHOR), Florica, Brandusa² (AUTHOR), Naik, Latha³ (AUTHOR), Sholter, Dalton⁴ (AUTHOR), Fournier, Pierre-André⁵ (AUTHOR), Girard, Tanya⁵ (AUTHOR), Liazoghli, Dalinda⁵ (AUTHOR), Baer, Philip A.⁶ (AUTHOR) philip.baer@rogers.com

Publikováno v: Rheumatology & Therapy. Oct2024, Vol. 11 Issue 5, p1165-1180. 16p.

Septin 7: Actin cross-organization is required for axonal association of Schwann cells

Autor: Dalinda Liazoghli, David R. Colman, Alejandro D. Roth, Felipe Perez De Arce

Publikováno v: Biological Research v.46 n.3 2013
SciELO Chile
CONICYT Chile
instacron:CONICYT
Biological Research, Volume: 46, Issue: 3, Pages: 243-249, Published: 2013
Biological Research, Vol 46, Iss 3, Pp 243-249 (2013)

Myelin sheaths present two distinct domains: compacted myelin spirals and flanking non-compacted cytoplasmic channels, where lipid and protein segregation is established by unknown mechanisms. Septins, a conserved family of membrane and cytoskeletal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b9ea9563a970fce96d6b0f3ff8b051
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000300004

Rapid assembly of functional presynaptic boutons triggered by adhesive contacts

Autor: Adam V. Kwiatkowski, David R. Colman, Fernando Suarez Sanchez, Dalinda Liazoghli, Craig C. Garner, R. Bruce Lennox, Peter Grutter, Anna Lisa Lucido, Gopakumar Gopalakrishnan, Sergio Leal-Ortiz, Peter Thostrup, Wiam Belkaid

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience. 29(40)

CNS synapse assembly typically follows after stable contacts between “appropriate” axonal and dendritic membranes are made. We show that presynaptic boutons selectively formde novofollowing neuronal fiber adhesion to beads coated with poly-d-lysi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a086afbbf6efe470d4a72f1512a4b0c0
https://pubmed.ncbi.nlm.nih.gov/19812321