Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Dalila Bachir-Cherif"'
Autor:
Dalila Bachir-Cherif, Sara Belli, Neil Parrott, Franz Schuler, Guido Steiner, Stefanie D. Krämer, Stanley E. Lazic, Stephanie Haller
Publikováno v:
Drug Metabolism and Disposition. 40:1603-1611
Beagle dogs are widely used in preclinical pharmacokinetic, safety, and formulation studies. However, little is known about intestinal and hepatic distribution of major enzymes and transporters involved in oral absorption and presystemic drug metabol
Autor:
Charles Alexandre Tournillac, Franz Schuler, Nicholas Flint, Volkmar Starke, Jean-Christophe Hoflack, Evelyne Chaput, Thomas Singer, Dalila Bachir-Cherif, Denise Blum, Annamaria Braendli-Baiocco, Nicole Justies, Genevieve Ubeaud-Sequier, Guido Steiner, Rachel Neff, Gonzalo Durán Pacheco, M. Haiker
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 41(8)
The bile duct-cannulated (BDC) rat is a standard animal model used in ADME experiments. The aim of this study was to investigate post-surgical alterations that are relevant to ADME investigations in BDC rats compared with sham- and non-operated anima