Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Dalibor, Breznan"'
Autor:
Subramanian Karthikeyan, Dalibor Breznan, Errol M. Thomson, Erica Blais, Renaud Vincent, Premkumari Kumarathasan
Publikováno v:
Toxics, Vol 12, Iss 4, p 290 (2024)
Diesel exhaust particles (DEPs) contribute to air pollution exposure-related adverse health impacts. Here, we examined in vitro, and in vivo toxicities of DEPs from a Caterpillar C11 heavy-duty diesel engine emissions using ultra-low-sulfur diesel (U
Externí odkaz:
https://doaj.org/article/8ff82d49855540898589d9f92a383d9d
Autor:
Ngoc Q. Vuong, Dalibor Breznan, Patrick Goegan, Julie S. O’Brien, Andrew Williams, Subramanian Karthikeyan, Premkumari Kumarathasan, Renaud Vincent
Publikováno v:
Particle and Fibre Toxicology, Vol 14, Iss 1, Pp 1-19 (2017)
Abstract Background Toxicity of airborne particulate matter (PM) is difficult to assess because PM composition is complex and variable due to source contribution and atmospheric transformation. In this study, we used an in vitro toxicoproteomic appro
Externí odkaz:
https://doaj.org/article/e6f2b9510afd4826b89d011e9fb5c621
Human lung epithelial cell A549 proteome data after treatment with titanium dioxide and carbon black
Autor:
Ngoc Q. Vuong, Patrick Goegan, Susantha Mohottalage, Dalibor Breznan, Marianne Ariganello, Andrew Williams, Fred Elisma, Subramanian Karthikeyan, Renaud Vincent, Premkumari Kumarathasan
Publikováno v:
Data in Brief, Vol 8, Iss , Pp 687-691 (2016)
Here, we have described the dataset relevant to the A549 cellular proteome changes after exposure to either titanium dioxide or carbon black particles as compared to the non-exposed controls, “Proteomic changes in human lung epithelial cells (A549)
Externí odkaz:
https://doaj.org/article/485c9a7d9919488282861892b5211465
Autor:
Premkumari Kumarathasan, Nazila Nazemof, Dalibor Breznan, Erica Blais, Hiroyuki Aoki, James Gomes, Renaud Vincent, Sadhna Phanse, Mohan Babu
Publikováno v:
The Analyst. 147:3692-3708
Application of mitochondrial proteomic analysis in toxicity screening of amorphous silica nanoforms. Concordance between SiNP exposure-related perturbations in mitochondrial proteins and cellular ATP responses.
Publikováno v:
Inhalation toxicology. 34(3-4)
Growing interest in non-animal-based models has led to the development of devices to expose cells to airborne substances. Cells/tissues grown at the air-liquid interface (ALI) are more representative of lung cells/tissuesWe tested and adapted a horiz
Autor:
Stéphane Bernatchez, Christine MacKinnon-Roy, Myriam Hill, Renaud Vincent, Dharani D. Das, Abdelhamid Sayari, Prem Kumarathasan, Dalibor Breznan
Publikováno v:
ACS Nano. 12:12062-12079
Nanoforms of mesoporous silica (mSiNPs) are increasingly applied in medicine, imaging, energy storage, catalysis, biosensors, and bioremediation. The impact of their physicochemical properties on health and the environment remain to be elucidated. In
Autor:
Christopher J. Stamler, Dalibor Breznan, Tracey A-M. Neville, France J. Viau, Errol Camlioglu, Daniel L. Sparks
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 8, Pp 1214-1221 (2000)
To examine the role that lipoprotein charge plays in cholesterol metabolism in vivo, we characterized the effects of an intravenous injection of 40 μmol of an uncharged phospholipid (phosphatidylcholine, PC) or an anionic phospholipid (phosphatidyli
Externí odkaz:
https://doaj.org/article/647507e8c1ab4c8fbda024b4bc4ff7c4
Autor:
Premkumari Kumarathasan, James Gomes, Dalibor Breznan, Filip Kunc, Nazila Nazemof, Myriam Hill, Renaud Vincent, Djordje Vladisavljevic, Linda J. Johnston
Silica nanoparticles (SiNPs) are used in a wide range of consumer products, engineering and medical applications, with likelihood of human exposure and potential health concerns. It is essential to generate toxicity information on SiNP forms and asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700559ee8555d48a6cfdbf77cf1018b7
https://doi.org/10.1039/d0an00380h
https://doi.org/10.1039/d0an00380h
Autor:
Marianne Ariganello, Fred Elisma, Aziz Khanchi, Prem Kumarathasan, Christine MacKinnon-Roy, Dalibor Breznan, Renaud Vincent, Dharani Das
Publikováno v:
Journal of Applied Toxicology. 38:1302-1315
Knowledge of biological reactivity and underlying toxicity mechanisms of airborne particulate matter (PM) is central to the characterization of the risk associated with these pollutants. An integrated screening platform consisting of protein profilin
Publikováno v:
Environmental Toxicology and Pharmacology. 86:103662
Although considerable inter-individual variability exists in health effects associated with air pollutant exposure, underlying reasons remain unclear. We examined whether innate differences in stress axis function modify lung glucocorticoid and macro