Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Dalia Somjen"'
Autor:
Fortune Kohen, Naftali Stern, Asaf Aizic, Dalia Somjen, Orli Sharon, Elena Izkhakov, Esther Knoll, Dan M. Fliss
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 182:81-86
Background Sorafenib improves progression-free survival in patients with progressive radioactive iodine-refractory differentiated thyroid carcinoma, but causes severe side effects. Estrogens may accelerate thyroid carcinoma cell growth. Our group rec
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 174:9-13
To further investigate the interaction between vitamin D system and estrogen-mimetic compounds in the human vasculature we studied the effect of the "less- calcemic" analog of 1,25(OH)2D3 (1,25D); JK 1624F2-2 (JKF) in the presence of selective estrog
Publikováno v:
Journal of the Endocrine Society
Estrogen exerts its effects through genomic and rapid extra-nuclear signaling pathways. The classic estrogen receptors, ERα and ERβ have demonstrated favorable effects on beta-cell function and survival but their clinical utility has been questione
Autor:
Dalia Somjen, Dan M. Fliss, Rona Limor, Orli Sharon, Esther Knoll, Asaf Aizic, Elena Izkhakov, Naftali Stern
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 159:26-30
Genes regulated cell-cell and cell-matrix adhesion and degradation of the extracellular matrix (ECM) have been screened as potential markers of malignant thyroid nodules. The mRNA expression levels of two of them, the ECM protein-1 (ECM1) and the typ
Autor:
Oleg Dolkart, Ettie Maman, Sarah Katzburg, Zachary T. Sharfman, Naftali Stern, Dalia Somjen, Eran Maman
Publikováno v:
Connective Tissue Research. 57:124-130
The most frequent complications after rotator cuff repair (RCR) are non-healing and re-tear. Age and gender are both proven risk factors for faulty RCR. This study analyzed the effects of female sex steroids and calciotropic hormones on tendon-derive
Publikováno v:
Immunology‚ Endocrine & Metabolic Agents in Medicinal Chemistry. 14:162-170
Publikováno v:
Expert Review of Endocrinology & Metabolism. 9:283-292
Background: Human cultured osteoblasts from pre-Ob, post-Ob or m-Ob express different mRNAs and respond to different hormones. Aims: To test expression and hormonal modulation of VDR and 1OHase and 1,25D production in hObs. Methods: hObs obtained fro
Publikováno v:
OBM Transplantation. 3:1-1
Background: Estradiol 17-beta (E2) enhances the function and survival of pancreatic beta-cells but its clinical use has been questioned due to concerns regarding oncogenic potential and feminizing effects in males. The G-protein coupled estrogen rece
Publikováno v:
The Bone & Joint Journal. :1575-1580
We analysed the effects of commonly used medications on human osteoblastic cell activity in vitro, specifically proliferation and tissue mineralisation. A list of medications was retrieved from the records of patients aged > 65 years filed in the dat
Publikováno v:
Journal of Endocrinological Investigation. 36:118-122
Vitamin D less-calcemic analog JKF 1624 F2-2 (JKF) and PTH 1–34 stimulate in human female cultured osteoblasts (Ob) DNA synthesis (DNA), creatine kinase specific activity (CK), 1α, 25 vitamin D hydroxylase mRNA (1 OHase) expression and 1, 25(OH)2D