Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Dalia H. A. Abdelaziz"'
Publikováno v:
Mediators of Inflammation, Vol 2019 (2019)
Chronic inflammation is a pivotal contributor to the liver damage mediated by hepatitis C virus (HCV). The NOD-like receptor, pyrin domain-containing 3 (NLRP3) inflammasome is activated by HCV in both hepatocytes and Kupffer cells. The aim of our stu
Externí odkaz:
https://doaj.org/article/fb2261ea245d479ea0e4cd3b4fd3e775
Autor:
Basant A. Abdulrahman, Waqas Tahir, Simrika Thapa, Rupali Walia, Dalia H. A. Abdelaziz, Hermann M. Schätzl
Publikováno v:
The Journal of Biological Chemistry
Prion diseases are fatal infectious neurodegenerative disorders in human and animals caused by misfolding of the cellular prion protein (PrPC) into the pathological isoform PrPSc. Elucidating the molecular and cellular mechanisms underlying prion pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed81a33d5f7d251045568d6c1825491
https://doi.org/10.1074/jbc.ra120.012596
https://doi.org/10.1074/jbc.ra120.012596
Autor:
Basant Abdulrahman, Dalia H. A. Abdelaziz, Lauren Vankuppeveld, Hermann M. Schätzl, Simrika Thapa
Publikováno v:
Biochemical and Biophysical Research Communications. 523:423-428
Prion diseases are fatal infectious neurodegenerative disorders in human and animals that are caused by misfolding of the cellular prion protein (PrPC) into the infectious isoform PrPSc. No effective treatment is available for prion diseases. Metform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80854e8f73046228136223dc3a337fb
https://doi.org/10.1016/j.bbrc.2019.12.074
https://doi.org/10.1016/j.bbrc.2019.12.074
Publikováno v:
Molecular Neurobiology. 57:2206-2219
Prion diseases are fatal infectious neurodegenerative disorders in human and animals caused by misfolding of the cellular prion protein (PrPC) into the infectious isoform PrPSc. These diseases have the potential to transmit within or between species,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28ac072f9500e172ecea7eb8dfe26c5c
https://doi.org/10.1007/s12035-020-01880-y
https://doi.org/10.1007/s12035-020-01880-y
Autor:
Hermann M. Schätzl, Robert McCorkell, Lauren Vankuppeveld, Dalia H. A. Abdelaziz, Simrika Thapa, Jenna Brandon, Justine Maybee
Publikováno v:
The Journal of Biological Chemistry
Chronic wasting disease (CWD) is a fatal neurodegenerative disease that affects cervids in North America and now Europe. No effective measures are available to control CWD. We hypothesized that active vaccination with homologous and aggregation-prone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4443819de2baae09e7ced0d1757197e2
https://doi.org/10.1074/jbc.ra118.004810
https://doi.org/10.1074/jbc.ra118.004810
Publikováno v:
The Journal of Biological Chemistry
Prions are protein-based infectious agents that autocatalytically convert the cellular prion protein PrPC to its pathological isoform PrPSc. Subsequent aggregation and accumulation of PrPSc in nervous tissues causes several invariably fatal neurodege
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043b246f35bcb18a7af6066bf1569d57
https://doi.org/10.1074/jbc.ra117.000713
https://doi.org/10.1074/jbc.ra117.000713
Publikováno v:
Curr Opin Pharmacol
Prions use cellular machineries for autocatalytic propagation by conformational conversion of the cellular prion protein into the pathological isoform PrP(Sc). Autophagy is a basic cellular degradation and recycling machinery that delivers cargo to l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41ee278440a2c92f0a8122d774568711
https://europepmc.org/articles/PMC6610235/
https://europepmc.org/articles/PMC6610235/
Publikováno v:
Mediators of Inflammation, Vol 2019 (2019)
Mediators of Inflammation
Mediators of Inflammation
Chronic inflammation is a pivotal contributor to the liver damage mediated by hepatitis C virus (HCV). The NOD-like receptor, pyrin domain-containing 3 (NLRP3) inflammasome is activated by HCV in both hepatocytes and Kupffer cells. The aim of our stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a186f5358b647562a88fab5890a124d
https://doaj.org/article/fb2261ea245d479ea0e4cd3b4fd3e775
https://doaj.org/article/fb2261ea245d479ea0e4cd3b4fd3e775
Publikováno v:
Clinics and Research in Hepatology and Gastroenterology. 40:465-470
Insulin resistance (IR) and type 2 diabetes mellitus (T2DM) are serious extrahepatic manifestations of chronic hepatitis C virus (HCV) infection. However, the mechanism underlying the IR in chronic HCV is obscure. Hepatokines are group of liver-deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c770a88d2fa218df4f17c735d51188
https://doi.org/10.1016/j.clinre.2015.12.003
https://doi.org/10.1016/j.clinre.2015.12.003
Autor:
Basant Abdulrahman, Hermann M. Schätzl, Li Lu, Simrika Thapa, Manel Ben Aissa, Dalia H. A. Abdelaziz
Publikováno v:
The Journal of Biological Chemistry
Prion diseases are fatal infectious neurodegenerative disorders in humans and other animals and are caused by misfolding of the cellular prion protein (PrPC) into the pathological isoform PrPSc. These diseases have the potential to transmit within or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98782d91c172c0d8bf86ecb35f0cab61
https://pubmed.ncbi.nlm.nih.gov/30154245
https://pubmed.ncbi.nlm.nih.gov/30154245