Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dalia Abdel Galil"'
Autor:
Nataliya Gorinski, Monika Bijata, Sonal Prasad, Alexander Wirth, Dalia Abdel Galil, Andre Zeug, Daria Bazovkina, Elena Kondaurova, Elizabeth Kulikova, Tatiana Ilchibaeva, Monika Zareba-Koziol, Francesco Papaleo, Diego Scheggia, Gaga Kochlamazashvili, Alexander Dityatev, Ian Smyth, Adam Krzystyniak, Jakub Wlodarczyk, Diethelm W. Richter, Tatyana Strekalova, Stephan Sigrist, Claudia Bang, Lisa Hobuß, Jan Fiedler, Thomas Thum, Vladimir S. Naumenko, Ghanshyam Pandey, Evgeni Ponimaskin
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Palmitoylation is a post translational modification that regulates GPCR activity. Here the authors show that palmitoylation of 5-HT1AR by the palmitoyltransferase enzyme ZDHHC21 contributes to depression-like behaviour in rodents and might be implica
Externí odkaz:
https://doaj.org/article/b7ca995a09f14264a865413198bdb889
Autor:
Daniel Wojciechowski, Alexander Wirth, Silke Glage, Volker Endeward, Monika Zaręba-Kozioł, Martin Fischer, Nicole Kerkenberg, Christa Hohoff, Samer Al-Samir, Dalia Abdel Galil, Andre Zeug, Boris V. Skryabin, Evgeni Ponimaskin, Weiqi Zhang, Stefan Thiemann, Franziska E. Mueller, Daria Guseva, Nataliya Gorinski, Jakub Wlodarczyk, Silke Schmidt
Publikováno v:
J Biol Chem
Barttin is the accessory subunit of the human ClC-K chloride channels, which are expressed in both the kidney and inner ear. Barttin promotes trafficking of the complex it forms with ClC-K to the plasma membrane and is involved in activating this cha
Autor:
Cornelius Faber, Christa Hohoff, Nicole Kerkenberg, Christiane Schettler, Lydia Wachsmuth, Evgeni Ponimaskin, Juergen Brosius, Dalia Abdel Galil, Maximilian Wewer, Mykola Kravchenko, Boris V. Skryabin, Nataliya Gorinski, Jens Buschert, Ilona Schneider, Mingyue Zhang, Kari Lavinia vom Werth, Oliver Ambrée, Dominik Grotegerd, Weiqi Zhang
Publikováno v:
Brain Structure and Function. 224:2213-2230
The palmitoyl acyltransferase ZDHHC7 belongs to the DHHC family responsible for the covalent attachment of palmitic acid (palmitoylation) to target proteins. Among synaptic proteins, its main targets are sex steroid receptors such as the estrogen rec
Autor:
Alexander Wirth, Josephine Labus, Dalia Abdel Galil, Yvonne Schill, Silke Schmidt, Tania Bunke, Nataliya Gorinski, Norihiko Yokoi, Masaki Fukata, Evgeni Ponimaskin
Publikováno v:
Journal of Biological Chemistry. 298:102048
The small GTPase Cdc42 exists in the form of two alternatively spliced variants that are modified by hydrophobic chains: the ubiquitously expressed Cdc42-prenyl and a brain-specific isoform that can be palmitoylated, Cdc42-palm. Our previous work dem
Autor:
Simon Bennet Sonnenberg, Vladimir S. Naumenko, Daria Guseva, Christoph Göhr, Stephan C. Bischoff, Dalia Abdel Galil, Andre Zeug, Sophie Kristin Schade, Nataliya Gorinski, Jonah Rauer, Evgeni Ponimaskin
Publikováno v:
Journal of Cell Science. 134
Morphological remodeling of dendritic spines is critically involved in memory formation and depends on adhesion molecules. Serotonin receptors are also implicated in this remodeling, though the underlying mechanisms remain enigmatic. Here, we uncover
Autor:
Simon Bennet, Sonnenberg, Jonah, Rauer, Christoph, Göhr, Nataliya, Gorinski, Sophie Kristin, Schade, Dalia, Abdel Galil, Vladimir, Naumenko, André, Zeug, Stephan C, Bischoff, Evgeni, Ponimaskin, Daria, Guseva
Publikováno v:
Journal of cell science. 134(4)
Morphological remodeling of dendritic spines is critically involved in memory formation and depends on adhesion molecules. Serotonin receptors are also implicated in this remodeling, though the underlying mechanisms remain enigmatic. Here, we uncover
Autor:
Yvonne, Schill, Monika, Bijata, Olga, Kopach, Volodymyr, Cherkas, Dalia, Abdel-Galil, Katrin, Böhm, Markus H, Schwab, Michiyuki, Matsuda, Valerie, Compan, Subhadip, Basu, Krystian, Bijata, Jakub, Wlodarczyk, Lucie, Bard, Nicholas, Cole, Alexander, Dityatev, Andre, Zeug, Dmitri A, Rusakov, Evgeni, Ponimaskin
Publikováno v:
Communications Biology
Activity-dependent remodeling of excitatory connections underpins memory formation in the brain. Serotonin receptors are known to contribute to such remodeling, yet the underlying molecular machinery remains poorly understood. Here, we employ high-re
Autor:
Natalia Ronkina, Natalya Gorinski, Fabrizia Cesca, Volodimir Cherkas, Gaga Kochlamazashvili, Tatiana Kuznetsova, Matthias Gaestel, Alexander Dityatev, Evgeni Ponimaskin, Juri Lafera, Dalia Abdel Galil, Patricia Marie-Jeanne Lievens
Publikováno v:
Molecular and cellular biology 36(17), 2208-2225 (2016). doi:10.1128/MCB.00144-16
The neural cell adhesion molecule (NCAM) mediates cell-cell and cell-matrix adhesion. It is broadly expressed in the nervous system and regulates neurite outgrowth, synaptogenesis, and synaptic plasticity. Previous in vitro studies revealed that palm
Autor:
Erhard Wischmeyer, Nataliya Gorinski, Marcus Niebert, Dalia Abdel-Galil, Matthias Fröhlich, Diethelm W. Richter, Galina Dityateva, Frank Döring, Andre Zeug, Evgeni Ponimaskin, Alexander Dityatev, Ute Renner, Daria Guseva, Erwin Neher, Andrew Woehler
Publikováno v:
Journal of Cell Science.
Serotonin receptors 5-HT(1A) and 5-HT(7) are highly coexpressed in brain regions implicated in depression. However, their functional interaction has not been established. In the present study we show that 5-HT(1A) and 5-HT(7) receptors form heterodim