Zobrazeno 1 - 10
of 251
pro vyhledávání: '"Dalei, Wu"'
Autor:
Yue Zhao, Tingting Zhang, Yinping Liang, Xiaoqing Xie, Hongwei Pan, Meng Cao, Shuhua Wang, Dalei Wu, Jing Wang, Chuandong Wang, Wei Hu
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
BackgroundThe continuous emergence and spread of polymyxin-resistant Acinetobacter baumannii pose a significant global health challenge, necessitating the development of novel therapeutic strategies. Aloe, with its long-standing history of medicinal
Externí odkaz:
https://doaj.org/article/a26aafcc79a946338a4cbe3b22235bb6
Autor:
Jianfeng Cui, Xiaochen Liu, Qinghong Shang, Shuna Sun, Shouzhen Chen, Jianping Dong, Yaofeng Zhu, Lei Liu, Yangyang Xia, Yong Wang, Lu Xiang, Bowen Fan, Jiafeng Zhan, Yadi Zhou, Pengxiang Chen, Renchang Zhao, Xiaofei Liu, Nianzeng Xing, Dalei Wu, Benkang Shi, Yongxin Zou
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract Background CDC6 is an oncogenic protein whose expression level fluctuates during the cell cycle. Although several E3 ubiquitin ligases responsible for the ubiquitin-mediated proteolysis of CDC6 have been identified, the deubiquitination path
Externí odkaz:
https://doaj.org/article/f6d55802213f4f25a464b9eea357d8fd
Autor:
Fengwei Li, Junjie Liu, Chao Liu, Ziyan Liu, Xiangda Peng, Yinyue Huang, Xiaoyu Chen, Xiangnan Sun, Sen Wang, Wei Chen, Dan Xiong, Xiaotong Diao, Sheng Wang, Jingjing Zhuang, Chuanliu Wu, Dalei Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Overexpressed pro-survival B-cell lymphoma-2 (BCL-2) family proteins BCL-2 and BCL-XL can render tumor cells malignant. Leukemia drug venetoclax is currently the only approved selective BCL-2 inhibitor. However, its application has led to an
Externí odkaz:
https://doaj.org/article/19437e85a22e4f4ebcfbfaff97f9f12a
Publikováno v:
Tehnički Vjesnik, Vol 31, Iss 6, Pp 2156-2160 (2024)
In recent years, the scale of China's power grid has been expanding, and the electricity consumption load has been rising year by year. Load forecasting plays a crucial role in ensuring the efficient coordination of power generation, transmission, an
Externí odkaz:
https://doaj.org/article/831b5186f4154f399a31343ac549cb0e
Publikováno v:
Tehnički Vjesnik, Vol 31, Iss 5, Pp 1514-1522 (2024)
With the rapid development of the power industry and the widespread adoption of smart meters, the occurrence of smart meter failures has also become more frequent. Consequently, the classification of smart meter faults has become a crucial task to en
Externí odkaz:
https://doaj.org/article/1018427452664e4a8f1cd597ae8638ca
Autor:
Vijayalakshmi K. Kumarasamy, Abhilasha Jairam Saroj, Yu Liang, Dalei Wu, Michael P. Hunter, Angshuman Guin, Mina Sartipi
Publikováno v:
Symmetry, Vol 16, Iss 4, p 448 (2024)
Machine learning (ML) methods, particularly Reinforcement Learning (RL), have gained widespread attention for optimizing traffic signal control in intelligent transportation systems. However, existing ML approaches often exhibit limitations in scalab
Externí odkaz:
https://doaj.org/article/46cf1629dc3d4ffa9dd213c8bd6a2d66
Autor:
Xiaotong Diao, Fei Ye, Meina Zhang, Xintong Ren, Xiaoxu Tian, Jingping Lu, Xiangnan Sun, Zeng Hou, Xiaoyu Chen, Fengwei Li, Jingjing Zhuang, Hong Ding, Chao Peng, Fraydoon Rastinejad, Cheng Luo, Dalei Wu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Whether hypoxia-inducible factors (HIFs) can be directly regulated by endogenous small molecules is a long-standing question. Here authors identified the metabolite oleoylethanolamide as a HIF-3α ligand and further revealed its mechanism of action.
Externí odkaz:
https://doaj.org/article/3f12a7f39e5c4af89eb48bcbee994f58
Autor:
Minyi Qian, Jun Liu, Danyang Zhao, Pengpeng Cai, Chuyue Pan, Wenxin Jia, Yingsheng Gao, Yufei Zhang, Nan Zhang, Yinan Zhang, Quan Zhang, Dalei Wu, Chengjie Shan, Meiling Zhang, Bernd Schnabl, Song Yang, Xu Shen, Lirui Wang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 233-256 (2022)
Background & Aims: The ligand-activated transcription factor, aryl hydrocarbon receptor (AHR) can sense xenobiotics, dietary, microbial, and metabolic cues. Roles of Ahr in intestinal epithelial cells (IECs) have been much less elucidated compared wi
Externí odkaz:
https://doaj.org/article/765f970da1ec401187be7dddfa8c4f39
Publikováno v:
Applied Artificial Intelligence, Vol 36, Iss 1 (2022)
The COVID-19 pandemic has spread rapidly and significantly impacted most countries in the world. Providing an accurate forecast of COVID-19 at multiple scales would help inform public health decisions, but recent forecasting models are typically used
Externí odkaz:
https://doaj.org/article/d1872c4b76ec414d8fc33486647faf18
Autor:
Chenglong Gao, Yazhou Xu, Zhuangzhuang Liang, Yunjie Wang, Qinghong Shang, Shengbin Zhang, Cunfang Wang, Mingmin Ni, Dalei Wu, Zhangjian Huang, Tao Pang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1867-1884 (2021)
Blood–brain barrier (BBB) damage after ischemia significantly influences stroke outcome. Compound LFHP-1c was previously discovered with neuroprotective role in stroke model, but its mechanism of action on protection of BBB disruption after stroke
Externí odkaz:
https://doaj.org/article/e6498db88e764b83be99f8c640600eee