Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Dale S Gregerson"'
Autor:
Nathan J Schuld, Stacy A Hussong, Rebecca J Kapphahn, Ute Lehmann, Heidi Roehrich, Abrar A Rageh, Neal D Heuss, Wendy Bratten, Dale S Gregerson, Deborah A Ferrington
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126768 (2015)
The immunoproteasome is upregulated by disease, oxidative stress, and inflammatory cytokines, suggesting an expanded role for the immunoproteasome in stress signaling that goes beyond its canonical role in generating peptides for antigen presentation
Externí odkaz:
https://doaj.org/article/9b2560ec4c69478f833ffd1608d41a17
Autor:
Deborah A Ferrington, Heidi Roehrich, Angela A Chang, Craig W Huang, Marcela Maldonado, Wendy Bratten, Abrar A Rageh, Neal D Heuss, Dale S Gregerson, Elizabeth F Nelson, Ching Yuan
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54347 (2013)
Recent studies have revealed roles for immunoproteasome in regulating cell processes essential for maintaining homeostasis and in responding to stress and injury. The current study investigates how the absence of immunoproteasome affects the corneal
Externí odkaz:
https://doaj.org/article/037c6e22685d48b79d733ac595a54f20
Autor:
Marcela Maldonado, Rebecca J Kapphahn, Marcia R Terluk, Neal D Heuss, Ching Yuan, Dale S Gregerson, Deborah A Ferrington
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56187 (2013)
Immunoproteasome is a protease abundant in immune cells and also present, albeit at lower concentrations, in cells outside the immune system. Recent evidence supports a novel role for the immunoproteasome in the cellular stress response potentially t
Externí odkaz:
https://doaj.org/article/cd1c5e0e859d494d9a13e93eba8c9d23
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
While pathogenic CD4 T cells are well known mediators of autoimmune uveoretinitis, CD8 T cells can also be uveitogenic. Since preliminary studies indicated that C57BL/6 mice were minimally susceptible to autoimmune uveoretinitis induction by CD8 T ce
Externí odkaz:
https://doaj.org/article/1ab2ebb0b0d346f2a542e1786ba460e2
Autor:
Eric F Tewalt, Jean M Grant, Erica L Granger, Douglas C Palmer, Neal D Heuss, Dale S Gregerson, Nicholas P Restifo, Christopher C Norbury
Publikováno v:
PLoS Pathogens, Vol 5, Iss 5, p e1000457 (2009)
Virus-specific CD8(+) T cells (T(CD8+)) are initially triggered by peptide-MHC Class I complexes on the surface of professional antigen presenting cells (pAPC). Peptide-MHC complexes are produced by two spatially distinct pathways during virus infect
Externí odkaz:
https://doaj.org/article/0c88fc6736a94c98b98d402d66bd3a91
Autor:
Scott W. McPherson, Neal D. Heuss, Md. Abedin, Heidi Roehrich, Mark J. Pierson, Dale S. Gregerson
Publikováno v:
Journal of Neuroinflammation. 19
BackgroundCharacterizing immune cells and conditions that govern their recruitment and function in autoimmune diseases of the nervous system or in neurodegenerative processes is an area of active investigation. We sought to analyze the origin of anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bde38cf4cb505aed824e229d969881a2
https://doi.org/10.1186/s12974-022-02660-2
https://doi.org/10.1186/s12974-022-02660-2
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-19 (2019)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Microglia are essential to the development of the CNS and its homeostasis. Our prior findings suggested a niche model to describe the behaviors of retinal microglia. Here, we ask whether new myeloid cells recruited to the retina are constr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56ea47cd8d1c4a1baf66fbd043c76c55
http://link.springer.com/article/10.1186/s12974-019-1546-9
http://link.springer.com/article/10.1186/s12974-019-1546-9
Publikováno v:
Molecular and Cellular Neuroscience. 85:70-81
Background Studies of antigen presentation in retina using mice that expressed green fluorescent protein (GFP) from a transgenic CD11c promoter found that retinal GFP hi cells possessed antigen presentation function. Subsequent studies found that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa1936d032931692a7506047519eb17
https://doi.org/10.1016/j.mcn.2017.09.002
https://doi.org/10.1016/j.mcn.2017.09.002
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose We previously demonstrated that passive transfer of lymphocytes from glaucomatous mice induces retinal ganglion cell (RGC) damage in recipient animals, suggesting a role for immune responses in the multifactorial pathophysiology of glaucoma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a5a46924853f312c3c6a384acc683c
https://doi.org/10.1167/iovs.61.14.18
https://doi.org/10.1167/iovs.61.14.18
Autor:
Ling Li, Scott W. McPherson, Andrea L. Gram, Neal D. Heuss, Mark Pierson, Dale S. Gregerson, Heidi Roehrich
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-19 (2018)
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-19 (2018)
Using mice expressing green fluorescent protein (GFP) from a transgenic CD11c promoter we found that a controlled optic nerve crush (ONC) injury attracted GFPhi retinal myeloid cells to the dying retinal ganglion cells and their axons. However, the o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a363570e0c48531556ae80d7ad08b98f
http://europepmc.org/articles/PMC6055350
http://europepmc.org/articles/PMC6055350