Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Dale Robert Mitchell"'
Autor:
Kenichiro Kataoka, Hiroaki Makino, Keiichiro Imaizumi, Brad Sherborne, Gen Unoki, Donald James Simpson, Naotaka Suzuki, C. John Harris, Richard K. Gordon, Tomomi Kosugi, Vicky Cunliffe, Heidi Kalloo-Hosein, Dale Robert Mitchell, Peter S Thomas, Kanji Komatsu, Midori Takimoto-Kamimura, Sugiura Satoshi, Mika Kambe, Yuri Sakai, Shinji Kobayashi, Aiko Fujino, Gita Patel, Yuko Yamakoshi, Julie A. Frearson, Oue Yasuhiro, Takenouchi Osami, Imai Minoru, Joelle Le, Yohei Matsueda
Publikováno v:
Journal of Medicinal Chemistry. 55:6700-6715
A novel class of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2) inhibitors was discovered through screening a kinase-focused library. A homology model of MAPKAP-K2 was generated and used to guide the initial SAR studies and t
Autor:
Ian Collins, Anil K Srivastava, Piyush K. Agarwal, John Frederick Atherall, Paul Lancett, Amit Kumar Singh, Pitt Gary Robert William, David T. Davies, Laura Andrau, Christopher Richard Steele, James M. Bennett, Stephanie Barker, James T Palmer, Mahipal Singh, Lorraine C. Axford, Carlie T. Gannon, Dushyant Kumar, David J. Haydon, Nicholas John Palmer, Daniel J. Price, Tarun Shukla, Daniel A. Offermann, Edward M. Tyndall, David G. Watson, Michael Blair, Helena Thomaides-Brears, Kelly Helen Anderson, Dale Robert Mitchell, Neil R. Stokes, Lloyd George Czaplewski, Stéphanie Pommier, Christopher J. Lunniss, Alastair Logan, Rashmi Saxena, B. Narasinga Rao
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(24)
The discovery and optimisation of a new class of benzothiazole small molecules that inhibit bacterial DNA gyrase and topoisomerase IV are described. Antibacterial properties have been demonstrated by activity against DNA gyrase ATPase and potent acti
Autor:
Hervé Van de Poël, Martin James Inglis Andrews, Nicholas John Palmer, Dale Robert Mitchell, Katja Conrath, Johan Neyts, Angus Murray Macleod, Pieter Leyssen
Rhinovirus (genus enterovirus) infections are responsible for many of the severe exacerbations of asthma and chronic obstructive pulmonary disease. Other members of the genus can cause life-threatening acute neurological infections. There is currentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47c97eeec8bfc74556c2a51878e652d
https://europepmc.org/articles/PMC4030314/
https://europepmc.org/articles/PMC4030314/