Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Dale J, Christensen"'
Autor:
Sawittree Sahakijpijarn, Chaeho Moon, Zachary N. Warnken, Esther Y. Maier, Jennie E. DeVore, Dale J. Christensen, John J. Koleng, Robert O. Williams, III
Publikováno v:
International Journal of Pharmaceutics: X, Vol 3, Iss , Pp 100073- (2021)
Remdesivir dry powder for inhalation was previously developed using thin film freezing (TFF). A single-dose 24-h pharmacokinetic study in hamsters demonstrated that pulmonary delivery of TFF remdesivir can achieve plasma remdesivir and GS-441524 leve
Externí odkaz:
https://doaj.org/article/dfe6a274c8314e9c8f760034807a44c2
Autor:
Miguel O. Jara, Zachary N. Warnken, Sawittree Sahakijpijarn, Rishi Thakkar, Vineet R. Kulkarni, Dale J. Christensen, John J. Koleng, Robert O. Williams
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2568 (2022)
Niclosamide is an FDA-approved anthelmintic that is being studied in clinical trials as a chemotherapeutic and broad-spectrum antiviral. Additionally, several other applications are currently in the preclinical stage. Unfortunately, niclosamide is a
Externí odkaz:
https://doaj.org/article/d5988db7ec374c72851dc142892f2f1e
Autor:
Pragnya Das, Suchismita Acharya, Varsha M. Prahaladan, Ogan K. Kumova, Shadi Malaeb, Sumita Behera, Beamon Agarwal, Dale J. Christensen, Alison J. Carey, Vineet Bhandari
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8547 (2021)
Bronchopulmonary dysplasia (BPD) is the most common complication of prematurity and a key contributor to the large health care burden associated with prematurity, longer hospital stays, higher hospital costs, and frequent re-hospitalizations of affec
Externí odkaz:
https://doaj.org/article/e3e0b26ebdc14c7fa8f29844186c1427
Autor:
Rosalie C. Sears, Goutham Narla, Michael Ohlmeyer, Dale J. Christensen, Brett Sheppard, Charles D. Lopez, Owen J. Sansom, Jennifer P. Morton, Katherine R. Pelz, Mary C. Thoma, Zina P. Jenny, Zhiping Wang, Zipei Feng, Tyler Risom, Brittany L. Allen-Petersen
Results of Kinase Inhibitor Screen including compound names, IC50s, and fold change compared to vehicle.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298272d763f56207a4f8b0acbfb53814
https://doi.org/10.1158/0008-5472.22421378.v1
https://doi.org/10.1158/0008-5472.22421378.v1
Autor:
Brian J. Druker, Dale J. Christensen, María D. Odero, Michael P. Vitek, Rosalie Sears, Jeffrey W. Tyner, Jessica Oddo, Christopher A. Eide, Raffaella Pippa, Ryan J. MacKenzie, Anupriya Agarwal
PDF file - 58KB, Combination index (CI) values.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185b438edbe87c73cbe82aed37ba8bb1
https://doi.org/10.1158/1078-0432.22449381
https://doi.org/10.1158/1078-0432.22449381
Autor:
Rosalie C. Sears, Goutham Narla, Michael Ohlmeyer, Dale J. Christensen, Brett Sheppard, Charles D. Lopez, Owen J. Sansom, Jennifer P. Morton, Katherine R. Pelz, Mary C. Thoma, Zina P. Jenny, Zhiping Wang, Zipei Feng, Tyler Risom, Brittany L. Allen-Petersen
Viability assays, Soft agar, Immunoprecipitation, Kinase inhibitor screen, and Patient outcome data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446537c73f9efea03dca3e1abae52f85
https://doi.org/10.1158/0008-5472.22421369.v1
https://doi.org/10.1158/0008-5472.22421369.v1
Autor:
Rosalie C. Sears, Goutham Narla, Michael Ohlmeyer, Dale J. Christensen, Brett Sheppard, Charles D. Lopez, Owen J. Sansom, Jennifer P. Morton, Katherine R. Pelz, Mary C. Thoma, Zina P. Jenny, Zhiping Wang, Zipei Feng, Tyler Risom, Brittany L. Allen-Petersen
Results of the Phosphokinase Array with phosphorylation sites, fold change relative to vehicle, and Kmeans clustering.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0088b85088bf7a980881e3de059f98
https://doi.org/10.1158/0008-5472.22421375.v1
https://doi.org/10.1158/0008-5472.22421375.v1
Autor:
Rosalie C. Sears, Goutham Narla, Michael Ohlmeyer, Dale J. Christensen, Brett Sheppard, Charles D. Lopez, Owen J. Sansom, Jennifer P. Morton, Katherine R. Pelz, Mary C. Thoma, Zina P. Jenny, Zhiping Wang, Zipei Feng, Tyler Risom, Brittany L. Allen-Petersen
Supplemental Figures S1-S9. S1: Kinase inhibitor screen and response of OP449 and INK128. S2: CI values for DT1154 combined with INK128 and viability curves. S3: Kmeans clusters and signaling in response to PP2A activators and INK128. S4: Oncoprint a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6733ae9b9a68b8a98c97af49a832aaad
https://doi.org/10.1158/0008-5472.22421372
https://doi.org/10.1158/0008-5472.22421372
Autor:
Brian J. Druker, Dale J. Christensen, María D. Odero, Michael P. Vitek, Rosalie Sears, Jeffrey W. Tyner, Jessica Oddo, Christopher A. Eide, Raffaella Pippa, Ryan J. MacKenzie, Anupriya Agarwal
PDF file - 94KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f5279656001f7f95968d5d48de18de
https://doi.org/10.1158/1078-0432.22449384.v1
https://doi.org/10.1158/1078-0432.22449384.v1
Autor:
Brian J. Druker, Dale J. Christensen, María D. Odero, Michael P. Vitek, Rosalie Sears, Jeffrey W. Tyner, Jessica Oddo, Christopher A. Eide, Raffaella Pippa, Ryan J. MacKenzie, Anupriya Agarwal
PDF file - 73KB, CML (Table 1) and AML (Table 2) Patient sample information.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0377ba428f825d16101282d07fc3f0
https://doi.org/10.1158/1078-0432.22449378
https://doi.org/10.1158/1078-0432.22449378