Výsledky vyhledávání - "Dale G. Ando"

Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV

Publikováno v: The New England journal of medicine. 370(10)

CCR5 is the major coreceptor for human immunodeficiency virus (HIV). We investigated whether site-specific modification of the gene ("gene editing")--in this case, the infusion of autologous CD4 T cells in which the CCR5 gene was rendered permanently

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb7c58fab510bbcdaaeb784d273080f
https://pubmed.ncbi.nlm.nih.gov/25035879

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Phase I/II trial of an allogeneic cellular immunotherapy in hormone-naïve prostate cancer

Autor: William G. Nelson, Michael A. Carducci, Barbara A. Biedrzycki, Flavia Borellini, Kristen Hege, Jonathan W. Simons, Bahar Mikhak, Richard C. Mulligan, Michael Lim, Steven Piantadosi, Shirley M. Clift, Dale G. Ando

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 12(11 Pt 1)

Purpose: To determine the toxicity, immunologic, and clinical activity of immunotherapy with irradiated, allogeneic, prostate cancer cells expressing granulocyte macrophage colony-stimulating factor (GM-CSF) in patients with recurrent prostate cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9076a70e31f07e2deafcd2fc72b977ef
https://pubmed.ncbi.nlm.nih.gov/16740763

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Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice

Autor: Jean E. Merrill, Dale G. Ando, Florence M. Hofman, Dwight H. Kono, David R. Hinton, Julie Clayton

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 89(2)

Experimental allergic encephalomyelitis (EAE) was generated in SJL and B10.PL mice by using the synthetic myelin basic protein peptides. Inflammation in brain and spinal cord preceded clinical signs of disease. Infiltrating lymphocytes were predomina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920a6565537f66d118dac52d71a472fe
https://pubmed.ncbi.nlm.nih.gov/1370583

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Analysis and Identification of Serological Tumor Antigens in Patients Treated with the GM-CSF-Gene Transduced-Autologous Tumor Vaccines (GVAX®) for Renal Cell Carcinoma

Autor: Ryo Kurita, Yukoh Nakazaki, Dale G. Ando, Shirley Clift, Fuyumi Takano, Kenzaburo Tani, Shigetaka Asano, Takao Hashiguchi

Publikováno v: Blood. 104:5279-5279

Vaccination of GM-CSF-transduced tumor cells (GVAX®) has been demonstrated to induce cellular and humoral immune response to tumors in animal studies as well as human clinical trials. We have recently done clinical trials of GVAX® using autologous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::056e543ba0bc5805c16ee8d8f8aa0b24
https://doi.org/10.1182/blood.v104.11.5279.5279

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582. Detection of Enhanced Serum Antibody Production to Renal Cell Cancer Proteins and Identification of Serological Tumor Antigens in Patients Treated with the GM-CSF-Gene Transduced-Autologous Tumor Vaccines (GVAX®)

Autor: Kenzaburo Tani, Shigetaka Asano, Takao Hashiguchi, Dale G. Ando, Yukoh Nakazaki, Shirley Clift

Publikováno v: Molecular Therapy. 9:S220

Vaccination of GM-CSF-transduced tumor cells (GVAX®) have been demonstrated to induce cellular and humoral immune response to tumors in animal studies as well as human clinical trials. We have recently done clinical trials of GVAX® using autologous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b57a8c2c9554e1db04dbb138936d6ca6
https://doi.org/10.1016/j.ymthe.2004.06.512

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Idiotype selection is an immunoregulatory mechanism which contributes to the pathogenesis of systemic lupus erythematosus

Autor: Niver Panosian-Sahakian, Joan L. Klotz, Dale G. Ando, Bevra H. Hahn, Betty P. Tsao, Fanny M. Ebling, Mitchell Kronenberg, Kenneth C. Kalunian

Publikováno v: Journal of Autoimmunity. 1:673-681

Several experiments are reviewed to support the following suggestions: (1) Idiotypes can be used to identify pathogenic autoantibodies in murine and human systemic lupus erythematosus; (2) Those idiotypes are targets for immune upregulation which cau

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::587f406f5b1820ac7ef3ab749a8f21dd
https://doi.org/10.1016/0896-8411(88)90058-3

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