Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Dale Edelbaum"'
Autor:
Akira Takashima, Lei Liu, David Shalhevet, Hiroyuki Matsue, Norikatsu Mizumoto, Francis Hui, Dale Edelbaum, M. Ryan Weil, Harold R. Garner, Jonathan D. Wren
Publikováno v:
Journal of Investigative Dermatology. 124(4):718-724
Immature dendritic cells (DC) at the environmental interfaces, such as the skin, constantly survey the tissue for the emergence of microbial products and pro-inflammatory mediators. Upon recognition of such "danger" signals, they undergo dynamic repr
Autor:
Akimichi Morita, Akira Takashima, Hiroyuki Matsue, Michael Walters, Dale Edelbaum, Keiko Matsue
Publikováno v:
Cancer Biology & Therapy. 3:1145-1151
Heterotypic hybrids created between dendritic cells (DC) and tumor cells represent an efficient approach for loading DC with tumor-associated antigens (TAA) and DC-tumor hybrid vaccines have shown promising outcomes in various preclinical and clinica
Autor:
Hiroyuki Matsue, Akira Takashima, Diana I. Mummert, Francis Hui, Dale Edelbaum, Mark E. Mummert
Publikováno v:
The Journal of Immunology. 169:4322-4331
Hyaluronan (HA) is a large glycosaminoglycan consisting of repeating disaccharide units of glucuronic acid and N-acetylglucosamine. HA is known to act as a filling material of extracellular matrices and as an adhesive substrate for cellular migration
Autor:
Keiko Matsue, Masahiro Kusuhara, Hiroyuki Matsue, Julie Loftus, Akira Takashima, Dale Edelbaum
Publikováno v:
European Journal of Immunology. 32:1035-1043
Dendritic cells (DC) play the dual task of initiating cellular immunity against potentially harmful foreign antigens (Ag), while maintaining immunological tolerance to self-Ag and environmental Ag. As an approach to induce Ag-specific suppression, we
Autor:
Kazuhiro Abeyama, Akira Takashima, Dale Edelbaum, Arie A. Vink, Clay J. Cockerell, William Eng, Paul R. Bergstresser, James V. Jester
Publikováno v:
Journal of Clinical Investigation. 105:1751-1759
Exposure of skin to ultraviolet (UV) radiation is known to induce NF-kappaB activation, but the functional role for this pathway in UV-induced cutaneous inflammation remains uncertain. In this study, we examined whether experimentally induced sunburn
Identification of a Novel, Dendritic Cell-associated Molecule, Dectin-1, by Subtractive cDNA Cloning
Autor:
Kiyoshi Ariizumi, Paul R. Bergstresser, Dale Edelbaum, Akira Takashima, Sojin Shikano, Akimichi Morita, Shan Xu, Guo Liang Shen, Tadashi Kumamoto, Robert Ritter
Publikováno v:
Journal of Biological Chemistry. 275:20157-20167
Dendritic cells (DC) are special subsets of antigen presenting cells characterized by their potent capacity to activate immunologically naive T cells. By subtracting the mRNAs expressed by the mouse epidermus-derived DC line XS52 with the mRNAs expre
Autor:
Richard K. Shadduck, Toshiyuki Kitajima, Paul R. Bergstresser, Georg Schuhmachers, Gary L. Gilmore, Shan Xu, Dale Edelbaum, Akira Takashima, Kiyoshi Ariizumi, R. Stan Taylor
Publikováno v:
Journal of Investigative Dermatology. 106:1023-1029
We have established long-term dendritic cell lines from the epidermis of newborn mice. These cell lines (XS series) proliferate maximally in response to granulocyte/macrophage-colony stimulating factor, as well as to CSF-1, which is produced by skin-
Publikováno v:
Journal of Investigative Dermatology. 105(6):837-843
Dendritic epidermal T cells (DETC) are skin-specific members of the epithelial γδ T-cell family in mice. We have reported previously that the growth of DETC is promoted by interleukin (IL)-2 in an autocrine fashion, or by IL-7, winch is secreted by
Publikováno v:
Experimental Dermatology. 2:133-138
Expression of the adhesion molecules ICAM-1 and LFA-1 (CD11a/CD18) on mouse epidermal Langerhans cells (LC) and on spleen dendritic cells (DC) from BALB/c mice was examined by staining with specific mAb and was evaluated by flow cytometry. LC were sh
Publikováno v:
Journal of Leukocyte Biology. 49:566-578
The accumulation of mononuclear phagocytes at sites of chronic inflammation is dependent on an increase in the rate of extravasation of blood-borne monocytes through the vascular endothelium into the connective tissue. Once the monocytes have emigrat