Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Dale E King"'
Autor:
Erin E Cummings, Linda P O'Reilly, Dale E King, Richard M Silverman, Mark T Miedel, Cliff J Luke, David H Perlmutter, Gary A Silverman, Stephen C Pak
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141542 (2015)
α1-antitrypsin deficiency (ATD) predisposes patients to both loss-of-function (emphysema) and gain-of-function (liver cirrhosis) phenotypes depending on the type of mutation. Although the Z mutation (ATZ) is the most prevalent cause of ATD, >120 mut
Externí odkaz:
https://doaj.org/article/d896cccbc3b349e0bf07f1e5d843ffba
Autor:
Sager J Gosai, Joon Hyeok Kwak, Cliff J Luke, Olivia S Long, Dale E King, Kevin J Kovatch, Paul A Johnston, Tong Ying Shun, John S Lazo, David H Perlmutter, Gary A Silverman, Stephen C Pak
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15460 (2010)
The development of preclinical models amenable to live animal bioactive compound screening is an attractive approach to discovering effective pharmacological therapies for disorders caused by misfolded and aggregation-prone proteins. In general, howe
Externí odkaz:
https://doaj.org/article/84a23b8725da453282e732e846ecd8d0
Autor:
Armando Ganoza, Krishnapriya Marangattu Prathapan, Wednesday Marie A. Sevilla, Jane Anne Yaworski, Geoffrey Bond, Feras Alissa, Dale E King, Vikram K. Raghu, Tracey Presel, Kimberly Ackerman, Jeffrey A. Rudolph
Publikováno v:
J Pediatr Gastroenterol Nutr
OBJECTIVES: Describe clinical characteristics, management, and outcome in a cohort of megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS) patients. METHODS: We conducted a retrospective chart review of MMIHS patients followed at a large
Autor:
Dale E King
Publikováno v:
Receptors & Clinical Investigation.
The Ephrin type B receptors (EphB) and their membrane bound ephrinB ligands are involved in diverse facets of cell physiology and pathophysiology. EphB-ephrinB signaling mediates synapse formation and plasticity by regulating the insertion, localizat
Autor:
David H. Perlmutter, Joon Hyeok Kwak, Stephen C. Pak, Olivia S. Long, Gary A. Silverman, Dale E. King, Sager J. Gosai
Publikováno v:
Methods in enzymology. 499
Protein misfolding, polymerization, and/or aggregation are hallmarks of serpinopathies and many other human genetic disorders including Alzheimer's, Huntington's, and Parkinson's disease. While higher organism models have helped shape our understandi
Autor:
Tong Ying Shun, David H. Perlmutter, Cliff J. Luke, Paul A. Johnston, Kevin J. Kovatch, Gary A. Silverman, Dale E. King, Olivia S. Long, Joon Hyeok Kwak, John S. Lazo, Sager J. Gosai, Stephen C. Pak
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15460 (2010)
PLoS ONE
PLoS ONE
The development of preclinical models amenable to live animal bioactive compound screening is an attractive approach to discovering effective pharmacological therapies for disorders caused by misfolded and aggregation-prone proteins. In general, howe
Autor:
Cliff J. Luke, Gary A. Silverman, Mark T. Miedel, Dale E. King, David H. Perlmutter, Linda P. O’Reilly, Erin E. Cummings, Stephen C. Pak, Richard M. Silverman
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 10, p e0141542 (2015)
PLoS ONE, Vol 10, Iss 10, p e0141542 (2015)
α1-antitrypsin deficiency (ATD) predisposes patients to both loss-of-function (emphysema) and gain-of-function (liver cirrhosis) phenotypes depending on the type of mutation. Although the Z mutation (ATZ) is the most prevalent cause of ATD, >120 mut
Publikováno v:
The Journal of nutrition. 130(1)
The ontogenetic development of intestinal digestive functions for avian species other than the domesticated chicken are not well documented. Therefore, this study was conducted to resolve the developmental patterns of some intestinal digestive functi
Autor:
Dale E. King, Kajal Lahiri
Publikováno v:
JAMA: The Journal of the American Medical Association. 272:524
Objective. —To determine the independent effect of socioeconomic, organizational, and professional liability factors on the odds of vaginal birth after cesarean delivery (VBAC) while controlling for important clinical factors. Design. —A retrospe
Autor:
Dale E King, Lawrence B. Schook, Jonathan E. Beever, Andrew G. Van Kessel, Laurie A. Rund, Mark Band, Juan J. Loor, Adrienne B Lane, Juan C. Marini, Benjamin P. Willing, H. Rex Gaskins, Shankar R Chowdhury
Publikováno v:
BMC Genomics, Vol 8, Iss 1, p 215 (2007)
BMC Genomics
BMC Genomics
Background To gain insight into host-microbe interactions in a piglet model, a functional genomics approach was used to address the working hypothesis that transcriptionally regulated genes associated with promoting epithelial barrier function are ac