Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Dale Chaput"'
Autor:
Shannon J. Ho, Dale Chaput, Rachel G. Sinkey, Amanda H. Garces, Erika P. New, Maja Okuka, Peng Sang, Sefa Arlier, Nihan Semerci, Thora S. Steffensen, Thomas J. Rutherford, Angel E. Alsina, Jianfeng Cai, Matthew L. Anderson, Ronald R. Magness, Vladimir N. Uversky, Derek A. T. Cummings, John C. M. Tsibris
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract VEGFR2 (Vascular endothelial growth factor receptor 2) is a central regulator of placental angiogenesis. The study of the VEGFR2 proteome of chorionic villi at term revealed its partners MDMX (Double minute 4 protein) and PICALM (Phosphatidy
Externí odkaz:
https://doaj.org/article/4a1dc85d29c94f1b8404ba416c726589
Autor:
Dinesh Devadoss, Kerri Surbaugh, Marko Manevski, Chatura Wickramaratne, Dale Chaput, Arianne Chung, Francisco de Leon, Hitendra S. Chand, Jaspreet S. Dhau
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Portable air purifiers help improve indoor air quality by neutralizing allergens, including animal dander proteins. However, there are limited in-vivo models to assess the efficacy of these devices. Here, we developed a novel animal model of
Externí odkaz:
https://doaj.org/article/800ca2c9e8644ca1946b08eed0e63eb1
Autor:
Clem Marsilia, Mrinalini Batra, Irina D. Pokrovskaya, Changqi Wang, Dale Chaput, Daria A. Naumova, Vladimir V. Lupashin, Elena S. Suvorova
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTSurvival of the apicomplexan parasite Toxoplasma gondii depends on the proper functioning of many glycosylated proteins. Glycosylation is performed in the major membranous organelles ER and Golgi apparatus that constitute a significant portio
Externí odkaz:
https://doaj.org/article/8b17efa4fcee4d43b024e78374b08cb9
Autor:
Anatoli V. Naumov, Chengqi Wang, Dale Chaput, Li-Min Ting, Carmelo A. Alvarez, Thomas Keller, Ahmed Ramadan, Michael W. White, Kami Kim, Elena S. Suvorova
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT Human toxoplasmosis is a life-threatening disease caused by the apicomplexan parasite Toxoplasma gondii. Rapid replication of the tachyzoite is associated with symptomatic disease, while suppressed division of the bradyzoite is responsible f
Externí odkaz:
https://doaj.org/article/dedcb6db27ca4847a544b7dca4c735cc
Autor:
Lauren M. Hawkins, Anatoli V. Naumov, Mrinalini Batra, Changqi Wang, Dale Chaput, Elena S. Suvorova
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Opportunistic parasites of the Apicomplexa phylum use a variety of division modes built on two types of cell cycles that incorporate two distinctive mechanisms of mitosis: uncoupled from and coupled to parasite budding. Parasites have evolve
Externí odkaz:
https://doaj.org/article/72c0646779014a829e1c23f5cc26305b
Publikováno v:
Cell Reports, Vol 35, Iss 1, Pp 108930- (2021)
Summary: Staphylococcus aureus possesses ten extracellular proteases with mostly unknown targets in the human proteome. To assist with bacterial protease target discovery, we have applied and compared two N-terminomics methods to investigate cleavage
Externí odkaz:
https://doaj.org/article/7df2a04757af4a5ba95e27780f674883
Autor:
Brittney D. Gimza, Jessica K. Jackson, Andrew M. Frey, Bridget G. Budny, Dale Chaput, Devon N. Rizzo, Lindsey N. Shaw
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
A key feature of the pathogenic success of S. aureus
Externí odkaz:
https://doaj.org/article/f0033305c3d94aa6b6c263f1c84939d3
Autor:
Santiago Rodriguez Ospina, Danielle M. Blazier, Marangelie Criado-Marrero, Lauren A. Gould, Niat T. Gebru, David Beaulieu-Abdelahad, Xinming Wang, Elizabeth Remily-Wood, Dale Chaput, Stanley Stevens, Vladimir N. Uversky, Paula C. Bickford, Chad A. Dickey, Laura J. Blair
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 851 (2022)
The microtubule-associated protein tau pathologically accumulates and aggregates in Alzheimer’s disease (AD) and other tauopathies, leading to cognitive dysfunction and neuronal loss. Molecular chaperones, like small heat-shock proteins (sHsps), ca
Externí odkaz:
https://doaj.org/article/2ece1a9b1c4a46c8bd5a5ee4da623119
Autor:
Ahmad Jalloh, Antwoine Flowers, Charles Hudson, Dale Chaput, Jennifer Guergues, Stanley M. Stevens, Paula C. Bickford
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6373 (2021)
Microglial activity in the aging neuroimmune system is a central player in aging-related dysfunction. Aging alters microglial function via shifts in protein signaling cascades. These shifts can propagate neurodegenerative pathology. Therapeutics requ
Externí odkaz:
https://doaj.org/article/1883ce5ecde7413aa377cf4a0de046c7
Autor:
Marangelie Criado-Marrero, Jonathan J. Sabbagh, Margaret R. Jones, Dale Chaput, Chad A. Dickey, Laura J. Blair
Publikováno v:
Cells, Vol 9, Iss 1, p 210 (2020)
Tau dysfunction is common in several neurodegenerative diseases including Alzheimer’s disease (AD) and frontotemporal dementia (FTD). Affective symptoms have often been associated with aberrant tau pathology and are commonly comorbid in patients wi
Externí odkaz:
https://doaj.org/article/9ded33bbd84a403cae4e1064f9df8b41