Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Dale C. Leitman"'
Autor:
Candice B. Herber, Chaoshen Yuan, Anthony Chang, Jen-Chywan Wang, Isaac Cohen, Dale C. Leitman
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-21 (2022)
Abstract Background Menopausal hormone therapy (MHT) is recommended for only five years to treat vasomotor symptoms and vulvovaginal atrophy because of safety concerns with long-term treatment. We investigated the ability of 2′,3′,4′-trihydroxy
Externí odkaz:
https://doaj.org/article/4e653d6fd6a24ca889bcc359d9ce47b8
Autor:
Jen-Chywan Wang, Candice B. Herber, Isaac Cohen, Chaoshen Yuan, Dale C. Leitman, Anthony Chang
Publikováno v:
Molecular Medicine. 28
Background Menopausal hormone therapy (MHT) is recommended for only five years to treat vasomotor symptoms and vulvovaginal atrophy because of safety concerns with long-term treatment. We investigated the ability of 2′,3′,4′-trihydroxychalcone
Autor:
Michael D. Wasserman, Dale C. Leitman, Colin A. Chapman, Tara R. Harris, Kathryn M. Benavidez
Publikováno v:
African Journal of Ecology. 57:429-436
Autor:
Elise F Saunier, Omar I Vivar, Andrea Rubenstein, Xiaoyue Zhao, Moshe Olshansky, Scott Baggett, Richard E Staub, Mary Tagliaferri, Isaac Cohen, Terence P Speed, John D Baxter, Dale C Leitman
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28333 (2011)
Long-term estrogen deficiency increases the risk of obesity, diabetes and metabolic syndrome in postmenopausal women. Menopausal hormone therapy containing estrogens might prevent these conditions, but its prolonged use increases the risk of breast c
Externí odkaz:
https://doaj.org/article/e1cff8bbcda24860a6082a0bc080acc6
Autor:
Sreenivasan Paruthiyil, Aleksandra Cvoro, Xiaoyue Zhao, Zhijin Wu, Yunxia Sui, Richard E Staub, Scott Baggett, Candice B Herber, Chandi Griffin, Mary Tagliaferri, Heather A Harris, Isaac Cohen, Leonard F Bjeldanes, Terence P Speed, Fred Schaufele, Dale C Leitman
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6271 (2009)
Estrogens produce biological effects by interacting with two estrogen receptors, ERalpha and ERbeta. Drugs that selectively target ERalpha or ERbeta might be safer for conditions that have been traditionally treated with non-selective estrogens. Seve
Externí odkaz:
https://doaj.org/article/ac45f5106f1c4ee9a8edf5000ecb05d8
Autor:
Abderrahmane Tagmount, Chaoshen Yuan, Chris D. Vulpe, Dale C. Leitman, Shawn Pan, Janet M. Ackerman, Ruthann A. Rudel, Paul Yaswen
Publikováno v:
Environmental Health Perspectives
Pan, Shawn; Yuan, Chaoshen; Tagmount, Abderrahmane; Rudel, Ruthann A; Ackerman, Janet M; Yaswen, Paul; et al.(2015). Parabens and Human Epidermal Growth Factor Receptor Ligand Cross-Talk in Breast Cancer Cells. Environmental Health Perspectives, 124(5). doi: 10.1289/ehp.1409200. UC Office of the President: California Breast Cancer Research Program. Retrieved from: http://www.escholarship.org/uc/item/42k5929h
Pan, Shawn; Yuan, Chaoshen; Tagmount, Abderrahmane; Rudel, Ruthann A; Ackerman, Janet M; Yaswen, Paul; et al.(2015). Parabens and Human Epidermal Growth Factor Receptor Ligand Cross-Talk in Breast Cancer Cells. Environmental Health Perspectives, 124(5). doi: 10.1289/ehp.1409200. UC Office of the President: California Breast Cancer Research Program. Retrieved from: http://www.escholarship.org/uc/item/42k5929h
Background: Xenoestrogens are synthetic compounds that mimic endogenous estrogens by binding to and activating estrogen receptors. Exposure to estrogens and to some xenoestrogens has been associated with cell proliferation and an increased risk of br
Autor:
Chaoshen Yuan, Isaac Cohen, Mary Tagliaferri, Candice B. Herber, Sreenivasan Paruthiyil, Dale C. Leitman, Moshe Olshansky, Terence P. Speed
Publikováno v:
Seminars in Reproductive Medicine. 30:14-22
Estrogens are frequently used in reproductive medicine. The Women's Health Initiative trial found that the risks of menopausal hormone therapy (MHT) exceed the benefits. The estrogens in MHT, however, were introduced prior to our understanding of the
Autor:
Terence P. Speed, Sreenivasan Paruthiyil, Omar I. Vivar, Elise F. Saunier, Candice B. Herber, Isaac Cohen, Dale C. Leitman, Mary Tagliaferri
Publikováno v:
Current Opinion in Pharmacology. 10:629-636
Estrogenic effects are mediated through two estrogen receptor (ER) subtypes, ERα and ERβ. Estrogens are the most commonly prescribed drugs to treat menopausal conditions, but by non-selectively triggering both ERα and ERβ pathways in different ti
Publikováno v:
Endocrinology. 151:1662-1667
3,3'-Diindolylmethane (DIM) is a natural compound found in cruciferous vegetables that has antiproliferative and estrogenic activity. However, it is not clear whether the estrogenic effects are mediated through estrogen receptor (ER)alpha, ERbeta, or
Autor:
Joan Climent, Emma Shtivelman, Mark Shoemaker, Isaac Cohen, Sylvia Fong, Dale C. Leitman, Chandi A. Griffin, Richard E. Staub, Ruth Chu, Xiaoyue Zhao
Publikováno v:
International Journal of Cancer. 127:1209-1219
Hormonal, targeted and chemotherapeutic strategies largely depend on the expression of their cognate receptors and are often accompanied by intolerable toxicities. Effective and less toxic therapies for estrogen receptor negative (ER-) breast cancers