Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Dale Brighouse"'
Autor:
Stéphanie Hugues, Melody A. Swartz, Christoph Scheiermann, Robert Pick, Ludovic J. Wrobel, Dale Brighouse, Guillaume Harlé, Julien Angelillo, Juan Dubrot, Laure Garnier, Anastasia O. Gkountidi
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97b74bf408b56577d84cd79640dae10
https://doi.org/10.1158/2326-6066.22543177.v1
https://doi.org/10.1158/2326-6066.22543177.v1
Autor:
Stéphanie Hugues, Melody A. Swartz, Christoph Scheiermann, Robert Pick, Ludovic J. Wrobel, Dale Brighouse, Guillaume Harlé, Julien Angelillo, Juan Dubrot, Laure Garnier, Anastasia O. Gkountidi
Several solid malignancies trigger lymphangiogenesis, facilitating metastasis. Tumor-associated lymphatic vessels significantly contribute to the generation of an immunosuppressive tumor microenvironment (TME). Here, we have investigated the ability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2363ce973488adde34a9b575d30608b9
https://doi.org/10.1158/2326-6066.c.6550168.v1
https://doi.org/10.1158/2326-6066.c.6550168.v1
Autor:
Stéphanie Hugues, Melody A. Swartz, Christoph Scheiermann, Robert Pick, Ludovic J. Wrobel, Dale Brighouse, Guillaume Harlé, Julien Angelillo, Juan Dubrot, Laure Garnier, Anastasia O. Gkountidi
Supplementary Figures and Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e7c234ce3b35c008e7ece180622896
https://doi.org/10.1158/2326-6066.22543180
https://doi.org/10.1158/2326-6066.22543180
Cancer immunotherapies utilize distinct mechanisms to harness the power of the immune system to eradicate cancer cells. Therapeutic vaccines, aimed at inducing active immune responses against an existing cancer, are highly dependent on the immunologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c16e42c6b181d66e77caa3abe0de3b
https://doi.org/10.1158/0008-5472.c.6509885
https://doi.org/10.1158/0008-5472.c.6509885
Supplementary Data Supplementary Material and Methods: Tumor experiments; CpG-B toxicity in vitro assay; Effect of i.t. CpG-B treatment on the growth of a distal tumor; Reactive oxygen species (ROS) detection. Supplementary Figures: Supplementary Fig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674a5a51042c557ca5bdbcc8285a0500
https://doi.org/10.1158/0008-5472.22417604
https://doi.org/10.1158/0008-5472.22417604
Autor:
Stéphanie Hugues, Jean-Marc Waldburger, Walter Reith, Caroline Pot, Magali Irla, Pauline Malinge, Dale Brighouse, Carla Lippens, Juan Dubrot, Leslie Guéry
Supplemental Information. Supplemental Materials and Methods Supplemental Fig. 1 : Chimeric mice selectively lacking MHCII expression on pDCs. Supplemental Fig. 2 : Similar T cell proliferation in µMT:WT and µMT pIII+IV-/-:WT chimeric mice. Supplem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fbf1c40501236cef5c142f5f50bfc41
https://doi.org/10.1158/0008-5472.22403936.v1
https://doi.org/10.1158/0008-5472.22403936.v1
Autor:
Christoph Scheiermann, Jennifer Niven, Stéphanie Hugues, Gaëlle Clavel, Monique Gannagé, Juan Dubrot, Natacha Bessis, Guillaume Harlé, Camille Kowalski, Dale Brighouse, Robert Pick
Publikováno v:
The Journal of experimental medicine, vol. 218, no. 6, pp. e20201776
Journal of Experimental Medicine, Vol. 218, No 6 (2021)
The Journal of Experimental Medicine
Journal of Experimental Medicine, Vol. 218, No 6 (2021)
The Journal of Experimental Medicine
The authors show that autophagy in lymphatic endothelial cells (LECs) dampens collagen-induced arthritis by regulating two distinct pathways: the promotion of T reg cells in LNs and the inhibition of S1P-dependent migration of pathogenic Th17 cells i
Autor:
Anastasia O, Gkountidi, Laure, Garnier, Juan, Dubrot, Julien, Angelillo, Guillaume, Harlé, Dale, Brighouse, Ludovic J, Wrobel, Robert, Pick, Christoph, Scheiermann, Melody A, Swartz, Stéphanie, Hugues
Publikováno v:
Cancer Immunology Research (2021)
Several solid malignancies trigger lymphangiogenesis, facilitating metastasis. Tumor-associated lymphatic vessels significantly contribute to the generation of an immunosuppressive tumor microenvironment (TME). Here, we have investigated the ability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d5bc287cface4484f7a7dbddc7066dcf
https://archive-ouverte.unige.ch/unige:152610
https://archive-ouverte.unige.ch/unige:152610
Autor:
Walter Reith, Stéphanie Hugues, Jean-Pierre Aubry-Lachainaye, Magali Irla, Fernanda V. Duraes, Carla Lippens, Dale Brighouse, Juan Dubrot, Mathilde Lacroix, Judith N. Mandl
Publikováno v:
Journal of Autoimmunity
Journal if autoimmunity
Journal of Autoimmunity, Elsevier, 2016, 75, pp.39-49. ⟨10.1016/j.jaut.2016.07.004⟩
Journal of Autoimmunity, Vol. 75 (2016) pp. 39-49
Journal of Autoimmunity, 2016, 75, pp.39-49. ⟨10.1016/j.jaut.2016.07.004⟩
Journal if autoimmunity
Journal of Autoimmunity, Elsevier, 2016, 75, pp.39-49. ⟨10.1016/j.jaut.2016.07.004⟩
Journal of Autoimmunity, Vol. 75 (2016) pp. 39-49
Journal of Autoimmunity, 2016, 75, pp.39-49. ⟨10.1016/j.jaut.2016.07.004⟩
Plasmacytoid dendritic cells (pDCs) have been shown to both mediate and prevent autoimmunity, and the regulation of their immunogenic versus tolerogenic functions remains incompletely understood. Here we demonstrate that, compared to other cells, pDC
Autor:
Juan Dubrot, Nadine Stokar-Regenscheit, Monique Gannagé, Hans Acha-Orbea, Christine Göpfert, Anjalie Schlaeppi, Stéphanie Hugues, Fernanda V. Duraes, Dale Brighouse, Natacha Madelon, Walter Reith, Guillaume Harlé
Publikováno v:
Life Science Alliance
Life Science Alliance, vol. 1, no. 6, pp. e201800164
Dubrot, Juan; Duraes, Fernanda V; Harlé, Guillaume; Schlaeppi, Anjalie; Brighouse, Dale; Madelon, Natacha; Göpfert, Christine; Stokar von Neuforn, Nadine; Acha-Orbea, Hans; Reith, Walter; Gannagé, Monique; Hugues, Stephanie (2018). Absence of MHC-II expression by lymph node stromal cells results in autoimmunity. Life science alliance, 1(6), e201800164. EMBO Press 10.26508/lsa.201800164
Life Science Alliance, Vol. 1, No 6 (2018) P. e201800164
Life Science Alliance, vol. 1, no. 6, pp. e201800164
Dubrot, Juan; Duraes, Fernanda V; Harlé, Guillaume; Schlaeppi, Anjalie; Brighouse, Dale; Madelon, Natacha; Göpfert, Christine; Stokar von Neuforn, Nadine; Acha-Orbea, Hans; Reith, Walter; Gannagé, Monique; Hugues, Stephanie (2018). Absence of MHC-II expression by lymph node stromal cells results in autoimmunity. Life science alliance, 1(6), e201800164. EMBO Press 10.26508/lsa.201800164
Life Science Alliance, Vol. 1, No 6 (2018) P. e201800164
MHCII-restricted antigen presentation by lymph node stromal cells is essential for regulatory T-cell proliferation and functions, and for the regulation of autoimmunity.
How lymph node stromal cells (LNSCs) shape peripheral T-cell responses rema
How lymph node stromal cells (LNSCs) shape peripheral T-cell responses rema