Výsledky vyhledávání - "Dale Beverly A"

Akademický článek

Caries induced cytokine network in the odontoblast layer of human teeth

Autor: Horst Jeremy A, Horst Orapin V, Samudrala Ram, Dale Beverly A

Publikováno v: BMC Immunology, Vol 12, Iss 1, p 9 (2011)

Abstract Background Immunologic responses of the tooth to caries begin with odontoblasts recognizing carious bacteria. Inflammatory propagation eventually leads to tooth pulp necrosis and danger to health. The present study aims to determine cytokine

Externí odkaz: https://doaj.org/article/dd453ba4b18b4276ba3262bed54129a6

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Akademický článek

PAR1- and PAR2-induced innate immune markers are negatively regulated by PI3K/Akt signaling pathway in oral keratinocytes

Autor: Dale Beverly A, Hacker Beth M, An Jonathan Y, DiJulio Dennis H, Rohani Maryam G, Chung Whasun O

Publikováno v: BMC Immunology, Vol 11, Iss 1, p 53 (2010)

Abstract Background Protease-Activated Receptors (PARs), members of G-protein-coupled receptors, are activated by proteolytic activity of various proteases. Activation of PAR1 and PAR2 triggers innate immune responses in human oral keratinocytes (HOK

Externí odkaz: https://doaj.org/article/70987d7d270c4be08dd723688b4a2531

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Akademický článek

Differential and coordinated expression of defensins and cytokines by gingival epithelial cells and dendritic cells in response to oral bacteria

Autor: Clark Edward A, Hacker Beth M, Horst Orapin V, Chino Takahiro, Yin Lei, Dale Beverly A, Chung Whasun O

Publikováno v: BMC Immunology, Vol 11, Iss 1, p 37 (2010)

Abstract Background Epithelial cells and dendritic cells (DCs) both initiate and contribute to innate immune responses to bacteria. However, much less is known about the coordinated regulation of innate immune responses between GECs and immune cells,

Externí odkaz: https://doaj.org/article/9778a746b8b4462a813c0a7703cd0299

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Akademický článek

Association of a genetic polymorphism (-44 C/G SNP) in the human DEFB1 gene with expression and inducibility of multiple β-defensins in gingival keratinocytes

Autor: Dommisch Henrik, Hacker Beth M, Fredericks L Page, Kalus Andrea A, Presland Richard B, Kimball Janet R, Dale Beverly A

Publikováno v: BMC Oral Health, Vol 9, Iss 1, p 21 (2009)

Abstract Background Human β-defensins (hBDs) are antimicrobial peptides with a role in innate immune defense. Our laboratory previously showed that a single nucleotide polymorphism (SNP) in the 5' untranslated region of the hBD1 gene (DEFB1), denote

Externí odkaz: https://doaj.org/article/80aa46d346f644fca5af1a81fe0308ad

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