Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Dale A Moulding"'
Publikováno v:
PLoS Pathogens, Vol 18, Iss 11, p e1010774 (2022)
Expression of the transcriptional transactivator protein Tax, encoded on the proviral plus-strand of human T-cell leukaemia virus type 1 (HTLV-1), is crucial for the replication of the virus, but Tax-expressing cells are rarely detected in fresh bloo
Externí odkaz:
https://doaj.org/article/e6cfb2e629184ebf968abc49e04f009d
Autor:
William J. Mason, Daniyal J. Jafree, Gideon Pomeranz, Maria Kolatsi-Joannou, Antje K. Rottner, Sabrina Pacheco, Dale A. Moulding, Anja Wolf, Christian Kupatt, Claire Peppiatt-Wildman, Eugenia Papakrivopoulou, Paul R. Riley, David A. Long, Elisavet Vasilopoulou
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Plasma ultrafiltration in the kidney occurs across glomerular capillaries, which are surrounded by epithelial cells called podocytes. Podocytes have a unique shape maintained by a complex cytoskeleton, which becomes disrupted in glomerular d
Externí odkaz:
https://doaj.org/article/37e6c94bbdf24a1381837add4474bfb3
Autor:
Owen Williams, Hugh J.M. Brady, Terence R.J. Lappin, Dimitris Kioussis, Dale A. Moulding, Inusha De Silva, Michelle Morrow, Alexander Thompson, Glenda J. McGonigle, David G. Grier, Sarah J. Horton
Supplementary Methods and Legends from Continuous MLL-ENL Expression Is Necessary to Establish a “Hox Code” and Maintain Immortalization of Hematopoietic Progenitor Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291039d748a8ee9cf20cb7040c222116
https://doi.org/10.1158/0008-5472.22364975.v1
https://doi.org/10.1158/0008-5472.22364975.v1
Autor:
Owen Williams, Hugh J.M. Brady, Terence R.J. Lappin, Dimitris Kioussis, Dale A. Moulding, Inusha De Silva, Michelle Morrow, Alexander Thompson, Glenda J. McGonigle, David G. Grier, Sarah J. Horton
Supplementary Figures S1-S4, Table 1 from Continuous MLL-ENL Expression Is Necessary to Establish a “Hox Code” and Maintain Immortalization of Hematopoietic Progenitor Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171ca47e665996a6c9333cd0066c052d
https://doi.org/10.1158/0008-5472.22364978
https://doi.org/10.1158/0008-5472.22364978
Autor:
Owen Williams, Hugh J.M. Brady, Terence R.J. Lappin, Dimitris Kioussis, Dale A. Moulding, Inusha De Silva, Michelle Morrow, Alexander Thompson, Glenda J. McGonigle, David G. Grier, Sarah J. Horton
The t[(11;19)(p22;q23)] translocation, which gives rise to the MLL-ENL fusion protein, is commonly found in infant acute leukemias of both the myeloid and lymphoid lineage. To investigate the molecular mechanism of immortalization by MLL-ENL we estab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c300a15dee575d3b3cc1b1aee9da2c1
https://doi.org/10.1158/0008-5472.c.6494468
https://doi.org/10.1158/0008-5472.c.6494468
Autor:
Kevin K. L. Lee, Emma Peskett, Charlotte M. Quinn, Rosanna Aiello, Liliya Adeeva, Dale A. Moulding, Philip Stanier, Erwin Pauws
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 11 (2018)
FGFR2c regulates many aspects of craniofacial and skeletal development. Mutations in the FGFR2 gene are causative of multiple forms of syndromic craniosynostosis, including Crouzon syndrome. Paradoxically, mouse studies have shown that the activation
Externí odkaz:
https://doaj.org/article/533c7c94dcf5409d880d7aa80046e4de
Autor:
Dale Bryant, Valda Pauzuolyte, Neil J. Ingham, Aara Patel, Waheeda Pagarkar, Lucy A. Anderson, Katie E. Smith, Dale A. Moulding, Yeh C. Leong, Daniyal J. Jafree, David A. Long, Amina Al-Yassin, Karen P. Steel, Daniel J. Jagger, Andrew Forge, Wolfgang Berger, Jane C. Sowden, Maria Bitner-Glindzicz
Publikováno v:
JCI Insight, 7 (3)
Norrie disease is caused by mutation of the NDP gene, presenting as congenital blindness followed by later onset of hearing loss. Protecting patients from hearing loss is critical for maintaining their quality of life. This study aimed to understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74114c37e1fa0e7db4315ef4a639383c
https://pubmed.ncbi.nlm.nih.gov/35132964
https://pubmed.ncbi.nlm.nih.gov/35132964
Autor:
Dale A. Moulding, Richard V. Giles, David G. Spiller, Michael R. H. White, David M. Tidd, Steven W. Edwards
Publikováno v:
Blood. 96:1756-1763
Mcl-1 is a member of the Bcl-2 protein family, which has been shown to delay apoptosis in transfection and/or overexpression experiments. As yet no gene knockout mice have been engineered, and so there is little evidence to show that loss of Mcl-1 ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7beaf699d75014605f3aad71dae1489
https://doi.org/10.1182/blood.v96.5.1756
https://doi.org/10.1182/blood.v96.5.1756
Publikováno v:
Chemical immunology and allergy. 83
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fdc6cb00a5c3609c3ea0e99bb03a25e7
https://pubmed.ncbi.nlm.nih.gov/12947986
https://pubmed.ncbi.nlm.nih.gov/12947986
Autor:
Dale Bryant, Valda Pauzuolyte, Neil J. Ingham, Aara Patel, Waheeda Pagarkar, Lucy A. Anderson, Katie E. Smith, Dale A. Moulding, Yeh C. Leong, Daniyal J. Jafree, David A. Long, Amina Al-Yassin, Karen P. Steel, Daniel J. Jagger, Andrew Forge, Wolfgang Berger, Jane C. Sowden, Maria Bitner-Glindzicz
Publikováno v:
JCI Insight, Vol 7, Iss 3 (2022)
Norrie disease is caused by mutation of the NDP gene, presenting as congenital blindness followed by later onset of hearing loss. Protecting patients from hearing loss is critical for maintaining their quality of life. This study aimed to understand
Externí odkaz:
https://doaj.org/article/c0067fb493e84e5eb2bb68d97a3e6a6d