Glutathione and arginine levels: Predictors for acetaminophen-associated asthma exacerbation?

Autor: Claudia R. Morris, David T. Mauger, Jung H. Suh, Wanda Phipatanakul, William J. Sheehan, James N. Moy, Ian M. Paul, Stanley J. Szefler, Daniel J. Jackson, Anne M. Fitzpatrick, Deborah Gentile, Erica Butler, Jennifer Maiolo, Sara Misplay, David Skoner, Glennys Smith, Jacqueline Pongracic, Rachel Robison, Iliana Flexas, Rajesh Kumar, Melanie Makhija, Nashmia Qamar, Christine Szychlinski, Fernando Martinez, Wayne Morgan, Cori Daines, Michael Daines, Valerie Bloss, Mark Brown, Katherine Chee, Sarah David, Clara S. Ehrman, Dima Ezmigna, Jamie Goodwin, Roni Grad, Anunya Hiranratta, Silvia Lopez, Andrea Paco, Janette Priefert, Natalie S. Provencio, Elizabeth Ryan, Monica Varela, Monica Vasquez, Rosemary Weese, Jesus Wences, Mindy Benson, Claudia Morris, Jung Suh, Jyothi Marbin, Jason Decker, Keonna Harrison, Dayna Long, Kelley Meade, Robert Mok, Cindy Nelson-Purdy, Dennis Ren, Hollie Stessel, William Sheehan, Jonathan Gaffin, Sachin Baxi, Lisa Bartnikas, Alisha Bouzaher, Christopher Burke, Matthew Cavanaugh, Julia Chen, Elizabeth Cunningham, Amparito Cunningham, James Friedlander, Enal Hindi, David Kantor, Lianne Kopel, Perdita Permaul, Deviko Rao, Melinda Rossi, Doris Schierembergg, Lynda Schneider, Jennifer Troung, Dale Umetsu, Joseph Zhou, Elliot Israel, Stanley Szefler, Fernando Holguin, Shean Aujla, John Broyles, Hey Chong, Patricia Dubin, Jonathan Finder, Todd Green, Lori Holt, Adam Kufen, Geoffrey Kurland, Rose Lanzo, David Nash, Julianne Parente, Catherine Smith, Jonathan Spahr, Daniel Weiner, Anne Fitzpatrick, Timothy Beaty, Shanae Wakefield Brown, Alice Bruce, Jennifer Dodds, Shaneka Douglas, Karen Freedle, Dawn Simon, Denise Whitlock, Ronina Covar, Tod Olin, Melanie Gleason, Gayle Spears, D. Sundstrom, Michael White, Kathryn Blake, John Lima, Jenny Batalla, Michelle Littlefield, Burnese Rutledge, Deanna Seymour, Jason Lang, Shanae Brown, Omar OquendoFlores, David Mauger, Ian Paul, Sue Boehmer, Loretta Doty, Beth Gern, Aimee Merchlinski, Jonathan Nelson, James Schmidt, Lindsay Texter, Angela Updegrave, Jennifer Zeller, Ronald Zimmerman, James Chmiel, Ross Myers, Kristie Ross, Daniel Craven, Amy DiMarino, Meeghan Hart, Leigh Kerns, Laurie Logan, Laura Veri, James Moy, Christopher Codispoti, Jun Fu, Grace Li, Diana Munoz-Mendoza, Shannon Stevens, Benjamin Thompson, Samantha Zitzer, Michaal Cabana, Stephen Lazarus, Ngoc Ly, Shannon Thyne, Jessica Bowman, Vicky Bowyer, Judy Gonzales-Vargas, Michelle McKean, Nancy Tran, Harsha Vardhan Kumar, Hengameh Raissy, Christina Batson, Lea Davies, Franceska Kelly, Esmeralda Morales, Abby Redway, Mary Spicher, Robert Lemanske, Daniel Jackson, Christine Sorkness, Lauren Kaminski, Megan Knutson, Shelly Olson, Sheila Turcsanyi, Tanya Watson, Stephen Peters, Adam Gower, Cheryl Wilmoth, Leonard Bacharier, Avraham Beigelman, Wanda Caldwell, Courtney Dula, Alysa Ellis, Caroline Horner, Lila Kertz, Tina Norris, Katherine Rivera-Spoljaric, Oscar Rodriguez, Robert Strunk

Publikováno v: The Journal of allergy and clinical immunology. 142(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e24d6f568d36768cb75ec8788067b925
https://pubmed.ncbi.nlm.nih.gov/29518418

c-Kit inhibitors prevent respiratory viral infection-induced acute asthma via the blockade of innate lymphoid cell activation

Autor: Ya-Jen Chang, Alan Chuan-Ying Lai, Han-Chih Wu, Dale Umetsu

Publikováno v: The Journal of Immunology. 196:53.1-53.1

Asthma is a major public health problem that affects nearly 10% of the general population and is thought to be mediated by allergen-specific Th2 cells, adaptive immunity and allergic inflammation. Current treatments for asthma generally focus on mini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8e818b4157a1e678e891803f0aed77f3
https://doi.org/10.4049/jimmunol.196.supp.53.1

RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance (IRC5P.465)

Autor: Yanping Xiao, Sanhong Yu, Baogong Zhu, Denis Bedoret, Xia Bu, Loise Francisco, Ping Hua, Jonathan Duke-Cohan, Dale Umetsu, Arlene Sharpe, Rosemarie DeKruyff, Gordon Freeman

Publikováno v: The Journal of Immunology. 192:125.14-125.14

We report that programmed death ligand 2 (PD-L2), a known ligand of PD-1, also binds to repulsive guidance molecule b (RGMb) which was originally identified in the nervous system as a co-receptor for bone morphogenetic proteins (BMPs). PD-L2 and BMP-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1129a97ad3277af9136330411d3049f2
https://doi.org/10.4049/jimmunol.192.supp.125.14

TIM-1 mediates the induction of ozone-induced airway hyperreactivity through the recognition of apoptotic cells in the lung (120.33)

Autor: Hye Young Kim, HyunHee Lee, Ya-Jen Chang, Ya-Ting Chaung, Stephanie Shore, Gordon Freeman, Rosemarie DeKruyff, Dale Umetsu

Publikováno v: The Journal of Immunology. 188:120.33-120.33

Asthma is a heterogeneous inflammatory disease of the lungs that has multiple triggers, including air pollution. The mechanisms however, by which non-allergic triggers such as air pollution cause asthma are poorly understood. In a model of air pollut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d45977eac1064d62ec7e0ffc7b36b03e
https://doi.org/10.4049/jimmunol.188.supp.120.33

TIM-3 is a receptor for phosphatidylserine and allelic variants differentially mediate uptake of apoptotic cells (130.41)

Autor: Xia Bu, Angela Ballesterous, Yee-Ling Chim, Cesar Santiago, Hyun-Hee Lee, Dale Umetsu, Jose Casasnovas, Rosemarie DeKruyff, Gordon Freeman

Publikováno v: The Journal of Immunology. 184:130.41-130.41

TIM-3 is a member of the T cell/transmembrane, Ig and mucin (TIM) gene family. TIM-3 is expressed on Th1 cells and dendritic cells and generates an inhibitory signal resulting in apoptosis of Th1 cells. We found that TIM-3 is receptor for phosphatidy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf6713432b0780fdd2fafa5eac760519
https://doi.org/10.4049/jimmunol.184.supp.130.41